Book Hotels in Wykoff, MN

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Top Wykoff hotels

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4 out of 5
101 11TH Avenue SW Rochester MN
Fully refundable
$111 nightly
The price is $128 total per night from Jan 11 to Jan 12
$128 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Great clean and friendly hotel. Rooms were spacious and had a notably nice smell when you first walk in.

Reviewed on Jan 1, 2026

Opens in a new windowEVEN Hotel Rochester - Mayo Clinic Area by IHG
Aspen Suites

Aspen Suites

3 out of 5
1211 2nd Street Rochester MN
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $175 total per night from Jan 11 to Jan 12
$175 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Clean room

Reviewed on Dec 30, 2025

Opens in a new windowAspen Suites
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $154 total per night from Jan 24 to Jan 25
$154 total
Jan 24 - Jan 25
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Breakfast to go was offered for the volleyball players.

Reviewed on Jan 4, 2026

Opens in a new windowHyatt House Rochester/Mayo Clinic Area
Hampton Inn Rochester-South

Hampton Inn Rochester-South

2.5 out of 5
1755 S Broadway Rochester MN
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $91 total per night from Feb 1 to Feb 2
$91 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. You'll appreciate the free ...
Fast check in-spacious room

Reviewed on Jan 9, 2026

Opens in a new windowHampton Inn Rochester-South
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
Fully refundable
$80 nightly
The price is $92 total per night from Jan 24 to Jan 25
$92 total
Jan 24 - Jan 25
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
The hotel was clean and a friendly staff at check in. We love that the hotel skyway is connected to Mayo, so could walk to appts. inside on a cold day. We also appreciated a noon check out.

Reviewed on Jan 1, 2026

Opens in a new windowHotel Indigo Rochester – Mayo Clinic Area by IHG
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $146 total per night from Jan 11 to Jan 12
$146 total
Jan 11 - Jan 12
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
No free breakfast

Reviewed on Jan 8, 2026

Opens in a new windowKahler Grand Hotel
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
1625 Broadway Ave S Rochester MN
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $89 total per night from Jan 18 to Jan 19
$89 total
Jan 18 - Jan 19
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
Good value for what you get. Clean room, comfortable bed, nice location, and good breakfast. Pool / hot tub area could use better ventilation and updating.

Reviewed on Jan 4, 2026

Opens in a new windowAmericInn by Wyndham Rochester Near Mayo Clinic
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $152 total per night from Jan 10 to Jan 11
$152 total
Jan 10 - Jan 11
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
We enjoy staying at Kahler Inn & Suites. So nice to be so close to Mayo Clinic. You don't have to go outside. You can walk from the hotel tp Mayo. Everyone is so friendly and the breakfast is great!

Reviewed on Jan 9, 2026

Opens in a new windowKahler Inn and Suites - Mayo Clinic Area
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3 out of 5
4353 Canal Pl SE Rochester MN
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $82 total per night from Jan 10 to Jan 11
$82 total
Jan 10 - Jan 11
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of the ...
Friendly staff and very clean

Reviewed on Jan 1, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Wykoff?
From well-thought-out amenities to extra space, kid-friendly hotels come with features that can help turn a regular family vacation into a fantastic one. These Wykoff properties make vacationing with little ones easy: The entire crew will love staying at Welcoming mid-century modern history-friendly home in bluff county.. A playground and a king bed are among the things that help make this hotel a sought-after option. Otherwise, spend your Wykoff break at Friendly-Farm Retreat. Make the most of a playground, a king bed and more here.
Where can I find cheap hotels in Wykoff?
At Travelocity you'll find really nice hotels in Wykoff at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Wykoff rather than in Wykoff. We may find you even better rates, too.
How do I find the best Wykoff hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Wykoff then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Wykoff?
The cheapest hotel in Wykoff is $82. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Wykoff?
There are 322 hotels in Wykoff on Travelocity.
What are the best hotels in Wykoff?
Wykoff has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Wykoff for you!
When is the best time to visit Wykoff?
If you want the joy of a fun-filled trip in peak season, visit Wykoff during May, July and August. If you'd prefer the peace of off-season, book a stay during quieter months, such as November, December and January.
When is the cheapest time to stay in Wykoff?
Based on historic data is usually the cheapest month to visit Wykoff. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Wykoff?
There are multiple hotels in Wykoff that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Wykoff. We have plenty of kid-friendly hotels in Wykoff to choose from on Travelocity!
Why book a hotel in Wykoff through Travelocity?
Because we have the top hotels in Wykoff! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Wykoff on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Wykoff hotel reviews by fellow wanderers

Hampton Inn Rochester-South

Hampton Inn Rochester-South

5 out of 5
Posted 21 hours ago
Travelocity Verified Review
"Fast check in-spacious room"
A verified traveler from Mason City stayed at Hampton Inn Rochester-South
Hampton Inn Rochester-South

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