Book Hotels in Wykoff, MN
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Top Wykoff hotels

Spark by Hilton Rochester South
4165 Maine Ave SE, Rochester, MN
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $84 total per night from Sep 7 to Sep 8
$84 total
Sep 7 - Sep 8
Total includes taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free perks ...
"Very basic, only toast and bagels for breakfast"
Reviewed on Aug 4, 2025

Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW, Rochester, MN
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $123 total per night from Aug 29 to Aug 30
$123 total
Aug 29 - Aug 30
Total includes taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
"Good food options around. Beds great. Office space and gym and pool very nice"
Reviewed on Aug 9, 2025

Hotel Indigo Rochester – Mayo Clinic Area by IHG
220 S Broadway, Rochester, MN
Fully refundable
$99 nightly
The price is $114 total per night from Aug 29 to Aug 30
$114 total
Aug 29 - Aug 30
Total includes taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"Great location downtown Rochester"
Reviewed on Jul 31, 2025

Aspen Select
1215 2nd St SW, Rochester, MN
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $151 total per night from Aug 12 to Aug 13
$151 total
Aug 12 - Aug 13
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
"Beds were very comfortable. Loved the terrace."
Reviewed on Aug 5, 2025

Kahler Grand Hotel
20 2nd Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $128 total per night from Aug 17 to Aug 18
$128 total
Aug 17 - Aug 18
Total includes taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Lots of construction around the building. You can no longer walk across to Mayo Clinic. The elevator does connect to the Mayo subway system. The hotel also has Mayo wheelchairs on hand. They offer valet parking. Parking is expensive. Keep this in mind when comparing costs. Construction is noisy during ..."
Reviewed on Aug 8, 2025

AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S, Rochester, MN
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $85 total per night from Aug 15 to Aug 16
$85 total
Aug 15 - Aug 16
Total includes taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
"👍"
Reviewed on Aug 7, 2025

Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $138 total per night from Aug 18 to Aug 19
$138 total
Aug 18 - Aug 19
Total includes taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
"Smells, out dated"
Reviewed on Aug 7, 2025

Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $92 total per night from Aug 17 to Aug 18
$92 total
Aug 17 - Aug 18
Total includes taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...
"They need to fix the bubbles in the hot hub onlu compkaint i ever have otherwise staff is great quiet place breakfast is awesome"
Reviewed on Aug 4, 2025

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
4353 Canal Pl SE, Rochester, MN
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $83 total per night from Aug 17 to Aug 18
$83 total
Aug 17 - Aug 18
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of the ...
"The staff was excellent!"
Reviewed on Aug 7, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Wykoff hotel reviews by fellow wanderers

Hyatt House Rochester/Mayo Clinic Area
5 out of 5
Posted 18 hours ago
Travelocity Verified Review
"Good food options around. Beds great. Office space and gym and pool very nice"
A verified traveler stayed at Hyatt House Rochester/Mayo Clinic Area
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