Explore 41 Luxury Hotels in Southeast Minnesota

Name: Regency Inn & Suites
Price range: $85 total

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Best Luxury Hotels in Southeast Minnesota

Brentwood Inn & Suites

123 Fourth Ave. NW, Rochester, MN

Fully refundableReserve now, pay when you stay

$125 nightly

$144 total

Aug 29 - Aug 30

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the 24-hour business ...

8.6/10 Excellent! (1,006 reviews)

"Proximity to Mayo clinic was excellent. The daily breakfast was very good, even after staying there for 13 days. The staff was friendly, efficient, and helpful. Parking was easy."

Reviewed on Aug 23, 2025

Kahler Grand Hotel

20 2nd Ave Sw, Rochester, MN

Fully refundableReserve now, pay when you stay

$124 nightly

$143 total

Aug 31 - Sep 1

Total with taxes and fees

This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...

8.2/10 Very Good! (1,537 reviews)

"We've spent a lot of time in Rochester and stayed at quite a few hotels. Overall, this is my second favorite. The Kahler is a pretty decent hotel located extremely conveniently to the main Mayo campus. If you need to be at the main campus, you really can't get more convenient than this hotel. We ..."

Reviewed on Aug 25, 2025

Kahler Inn and Suites - Mayo Clinic Area

9 3rd Ave Nw, Rochester, MN

Fully refundableReserve now, pay when you stay

$123 nightly

$142 total

Aug 31 - Sep 1

Total with taxes and fees

This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...

7.8/10 Good! (1,403 reviews)

"Onsite parking option"

Reviewed on Aug 25, 2025

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw, Rochester, MN

Fully refundableReserve now, pay when you stay

$80 nightly

$92 total

Aug 29 - Aug 30

Total with taxes and fees

2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...

AmericInn by Wyndham Northfield

1320 Bollenbacher Dr, Northfield, MN

Fully refundableReserve now, pay when you stay

$106 nightly

$117 total

Sep 14 - Sep 15

Total with taxes and fees

This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...

Coratel Inn & Suites By Jasper Northfield

1420 Riverview Dr, Northfield, MN

Fully refundableReserve now, pay when you stay

$68 nightly

$76 total

Aug 31 - Sep 1

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...

Days Inn by Wyndham Winona

420 Cottonwood Dr, Hwy 14 and Hwy 61, Winona, MN

Fully refundableReserve now, pay when you stay

$80 nightly

$89 total

Aug 31 - Sep 1

Total with taxes and fees

A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests ...

Regency Inn & Suites

4040 Highway 60 W, I-35 Exit# 56, Faribault, MN

Fully refundableReserve now, pay when you stay

$77 nightly

$85 total

Aug 31 - Sep 1

Total with taxes and fees

An indoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi in ...

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Southeast Minnesota Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Southeast Minnesota luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Southeast Minnesota to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Southeast Minnesota will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Southeast Minnesota, and plan your next opulent escape.

Southeast Minnesota hotels essential information

Accommodation	927 hotels
Lowest Price	$76
Highest Price	$144
Popular hotels	Kahler Grand Hotel, Med City Inn & Suites - Mayo Clinic Area, AmericInn by Wyndham Northfield, Coratel Inn & Suites By Jasper Northfield, Kahler Inn and Suites - Mayo Clinic Area, Brentwood Inn & Suites, Days Inn by Wyndham Winona, Regency Inn & Suites