Book Hotels in Sedgewickville, MO
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Top Sedgewickville hotels

Secluded 5-Bedroom Lodge with Private Lake – Perfect for Large Groups!
Perryville MO
This lodge featured laundry facilities and barbecue grills.
A peaceful, secluded cabin with a gorgeous view of the lake. Spacious rooms and beautifully decorated. The hosts were welcoming and responsive to any questions that came up before or during our stay. We are already looking forward to our next trip!
Reviewed on Jul 14, 2025

Silo Farm Haus- located in the heart of wine country!
Ste. Genevieve MO
$326 nightly
The price is $348 total per night from Mar 7 to Mar 8
$348 total
Mar 7 - Mar 8
Total with taxes and fees
This farm stay features laundry facilities.
We felt welcomed from the minute we stepped inside. My husband and I spent Valentines Day weekend touring the local wineries and rather than going out for dinner with tons of other people, we enjoyed pizza and wine at the Silo.
Reviewed on Feb 16, 2026

Drury Inn & Suites Jackson MO
225 Drury Lane Jackson MO
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $85 total per night from Mar 10 to Mar 11
$85 total
Mar 10 - Mar 11
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
This was our first stay at a Drury hotel
Reviewed on Mar 5, 2026

Tru By Hilton Cape Girardeau
2520 Veterans Memorial Dr Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $111 total per night from Mar 11 to Mar 12
$111 total
Mar 11 - Mar 12
Total with taxes and fees
This hotel features an indoor pool and a gym. Guests will appreciate freebies like daily breakfast and free self parking. Staff at the 24-hour front desk can ...
New! Love the lobby layout, design and seating. Staff is super friendly and welcoming. Location is right next to the sports complex.
Reviewed on Feb 24, 2026

Holiday Inn Express & Suites Perryville by IHG
2020 Jefferson St Perryville MO
Fully refundable
$103 nightly
The price is $118 total per night from Apr 5 to Apr 6
$118 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Room was great, front desk was professional but friendly. Breakfast was excellent. Spotless — both room and lobby.
Reviewed on Feb 24, 2026

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $91 total per night from Mar 8 to Mar 9
$91 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Clean , friendly, great location
Reviewed on Mar 4, 2026

Quality Inn Cape Girardeau North
2011 North Kingshighway Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $68 total per night from Mar 11 to Mar 12
$68 total
Mar 11 - Mar 12
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like English breakfast and WiFi in public ...
Noisy. Could hear noise from parking lot and from upstairs. Did not like required refundable $50 deposit. After hearing a shower running from another room, our shower leaked from the wall connection. Staff said there was no one available to fix. Staff offered to move us. but we were unpacked ready ...
Reviewed on Mar 4, 2026

Days Inn by Wyndham Perryville
1500 Liberty Street Perryville MO
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $82 total per night from Mar 8 to Mar 9
$82 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...

Comfort Suites Jackson-Cape Girardeau
2904 Old Orchard Rd Jackson MO
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $100 total per night from Mar 8 to Mar 9
$100 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Sedgewickville hotel reviews by fellow wanderers

Drury Inn & Suites Jackson MO
5 out of 5
Posted 7 hours ago
Travelocity Verified Review
"This was our first stay at a Drury hotel"
A verified traveler stayed at Drury Inn & Suites Jackson MO






