Book Hotels in Murphy, MO
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Top Murphy hotels

Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $106 total per night from Dec 8 to Dec 9
$106 total
Dec 8 - Dec 9
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
Was a very nice stay! Bandanas next door is so good!!
Reviewed on Nov 29, 2025

Drury Inn & Suites St. Louis Union Station
201 S 20th St St. Louis MO
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $142 total per night from Dec 8 to Dec 9
$142 total
Dec 8 - Dec 9
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
Clean room. Wonderful staff. And great freebies!!!
Reviewed on Nov 30, 2025

21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$156 nightly
The price is $183 total per night from Dec 28 to Dec 29
$183 total
Dec 28 - Dec 29
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Staff is wonderful. We checked in late after a long journey and they could not have been nicer to us at check in also in the restaurant and bar. We loved the vibe and the location. I’d return again if ever in the area.
Reviewed on Dec 2, 2025

Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $115 total per night from Dec 13 to Dec 14
$115 total
Dec 13 - Dec 14
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Love the breakfast buffet! Something for everyone. Staff is always friendly and helpful. I plan to stay at this hotel anytime I’m near it. I always feel so welcome.
Reviewed on Nov 30, 2025

Pear Tree Inn St. Louis Near Union Station
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $110 total per night from Dec 8 to Dec 9
$110 total
Dec 8 - Dec 9
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Our stay was great, minus the fact that the hot tub was out of service. It was one of the reasons we chose this hotel so we (the parents) were disappointed. But the kids loved the pool! There were plenty of breakfast options, though adding one more waffle maker would alleviate the long wait to make ...
Reviewed on Dec 1, 2025

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $120 total per night from Dec 8 to Dec 9
$120 total
Dec 8 - Dec 9
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
Great
Reviewed on Dec 2, 2025

Home2 Suites by Hilton St. Louis Downtown
1221 Locus Street St. Louis MO
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $89 total per night from Dec 10 to Dec 11
$89 total
Dec 10 - Dec 11
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Traveling on business? Take advantage of the 24-hour business center ...
Great customer service horrible location
Reviewed on Nov 29, 2025

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
1088 South Highway Drive Fenton MO
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $98 total per night from Dec 14 to Dec 15
$98 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Everything related to our stay here was great until I needed assistance with additional towels and toilet paper in our room and had to ask the gal working the front desk on the second night we were there. It was a Friday and her nametag said "Manager" which was alarming because she was extremely ...
Reviewed on Dec 1, 2025

Forest Park Hotel by MDR
5915 Wilson Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$83 nightly
The price is $97 total per night from Dec 7 to Dec 8
$97 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling for business? Take advantage of the 24-hour business center, ...
My entire room was clean, the staff are nice, the amenities were efficient…
Reviewed on Nov 28, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Murphy hotel reviews by fellow wanderers

21C Museum Hotel St Louis
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Staff is wonderful. We checked in late after a long journey and they could not have been nicer to us at check in also in the restaurant and bar. We loved the vibe and the location. I’d return again if ever in the area. "
A verified traveler stayed at 21C Museum Hotel St Louis
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