Mesopotamia Vacation Packages 2025/2026 from $893

Mesopotamia flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Infinito Hotel

Palermo

$893

per person

Oct 20 - Oct 27

found 1 day ago

Roundtrip non-stop flight included

Chicago (CHI) to Buenos Aires (BUE)

A full-service spa and a hot tub are featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. Enjoy the sauna and free buffet breakfast each morning.

Live Soho Boutique Apartments Devoto

Villa Devoto

$1,068

per person

Oct 20 - Oct 27

found 1 day ago

Roundtrip non-stop flight included

Chicago (CHI) to Buenos Aires (BUE)

Free WiFi in public areas, a communal living room, and express check-out are available at this condo. Dry cleaning, laundry facilities, and concierge services are also on offer.

Mio Buenos Aires

Recoleta

Save 100% on your flight

$1,621

per person

Oct 20 - Oct 27

found 1 day ago

Roundtrip non-stop flight included

Chicago (CHI) to Buenos Aires (BUE)

A full-service spa, an indoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport shuttle. Enjoy the gym and free full breakfast each morning.

Faena Hotel Buenos Aires

Puerto Madero

Save 100% on your flight

$2,369

per person

Oct 20 - Oct 27

found 1 day ago

Roundtrip non-stop flight included

Chicago (CHI) to Buenos Aires (BUE)

A full-service spa, 3 restaurants, and an outdoor pool are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport shuttle. Enjoy the 24-hour gym and unwind at the bar/lounge and poolside bar.

Bulnes Eco Suites

Palermo

$1,017

per person

Oct 20 - Oct 27

found 1 day ago

Roundtrip non-stop flight included

Chicago (CHI) to Buenos Aires (BUE)

This aparthotel features a restaurant, a rooftop terrace, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, and airport shuttle. A terrace, a snack bar/deli, and a communal living room are also on offer.

Top Mesopotamia hotels deals

Hotel y Spa Termas del Este

Presidente Raúl alfonsín 877, Federacion

Get rates

A full-service spa, an outdoor pool, and a restaurant are all featured at this hotel. Business travelers can take advantage of the free WiFi in public areas. Enjoy the indoor pool and free perks like buffet breakfast and free self parking.

Hotel La Bahia

San Lorenzo 553, Federacion, Entre Rios (province)

Get rates

A full-service spa and an outdoor pool are featured at this hotel. Relax with a drink at the bar/lounge and enjoy perks like free self parking and free WiFi. A terrace, luggage storage, and concierge services are also on offer.

Hathor Concordia

Ruta Nacional 14-km 264.5, Concordia, Entre Rios

Free Cancellation

Reserve now, pay when you stay

Get rates

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the indoor pool and free continental breakfast each morning.

Costarenas Hotel & Spa

12 de Abril y Quiros, Colon, Entre Rios

$108 nightly

$108 total

Sep 11 - Sep 12

A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Enjoy the indoor pool and free perks like buffet breakfast and WiFi in public areas. You'll appreciate the gym, bar/lounge, and laundry facilities.

Maran Suites & Towers - Hotel & Spa

Av. Alameda de la Federacion y Mitre, Parana, Entre Rios

$95 nightly

$95 total

Sep 29 - Sep 30

A full-service spa, a gym, and a restaurant are all featured at this traditional hotel. There's fun for all ages with a playground and an arcade/game room, and families will appreciate the onsite laundry facilities. Enjoy the sauna and free perks like buffet breakfast and WiFi in public areas.

Agustín 1 Apart

130 Gral. Pedro Ferré, Parana, Entre Ríos

Free Cancellation

Reserve now, pay when you stay

$63 nightly

$63 total

Sep 10 - Sep 11

This aparthotel features express check-in, a virtual front desk, and self parking. If you want to take your pet along, this pet-friendly property offers everything you'll need for your pet including food and water bowls. Express check-out is also provided.

Kitchen

Pet friendly

Don't see what you're looking for?

See all available properties in Mesopotamia

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

El Palmar National Park

Explore the great outdoors at El Palmar National Park, a lovely green space in Ubajay.

Amé las 20 hectáreas de parque y jardines de este Palacio

San José Palace

You can spend an afternoon exploring the galleries in San José Palace in Caseros.

Termas de Federacion

Bring your family to Termas de Federacion and have a fun-filled day at this amusement park in Federacion. Stroll along the beaches or discover the area's waterfalls.

Frequently asked questions

How much are vacation packages to Mesopotamia?

Prepare to be pleasantly surprised — you can find yourself in Mesopotamia for just $893. At Travelocity, we save you money and stress with our awesome vacation package deals. With flights, hotels and experiences all ready to be snapped up, why put it off?

Where can I get the best vacation package deals for Mesopotamia?

Travelocity can help you find a terrific Mesopotamia package deal. With more than 400 air carriers and 1,000,000 properties around the world, we're sure you'll find one that works for you.

Why should I purchase my Mesopotamia vacation package via Travelocity?

Whether you're planning an epic vacation or a last-minute escape, we have plenty of attractive destinations to choose from at an affordable rate. And on top of that, we provide round-the-clock support, top-notch service and a Price Match Guarantee. Save yourself money and time and secure your dream vacation now.

Can I save on my Mesopotamia car rental if I bundle it with a hotel or flight?

Definitely. And our Mesopotamia vacation packages are the best way to do it. In just a few clicks you can save money and time by booking everything in one place. Collect the keys to your rental car then set your own course. Need to fill your itinerary? Throw some tours or experiences into your package and save on those too.

What is there to do in Mesopotamia?

Mesopotamia has hidden surprises at every turn, but be sure you plan a visit to both Termas de Federacion and Termas Concepcion Entrerios while you're in town. These landmarks should be on your to-do list.