Explore 1 Luxury Hotels in Hartsville

Name: The Mantissa Hotel
Price range: $156 total
Rating: 9

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Best Luxury Hotels in Hartsville

The Mantissa Hotel

130 East Carolina Ave Hartsville SC

Fully refundableReserve now, pay when you stay

$140 nightly

$156 total

Jan 11 - Jan 12

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Enjoy the a rooftop terrace and free perks like on-the-go breakfast and free self parking. A business ...

9/10 Wonderful! (271 reviews)

Excellent staff and in the heart of a beautiful downtown.

Reviewed on Dec 5, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hartsville Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Hartsville luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Hartsville to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Hartsville will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Hartsville, and plan your next opulent escape.