Explore 32 Luxury Hotels in Greenville - Spartanburg

Start date: Check-in selected.
To Date
End date: Check-out

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Best Luxury Hotels in Greenville - Spartanburg

The Westin Poinsett Greenville

The Westin Poinsett Greenville

120 South Main St, Greenville, SC
Fully refundableReserve now, pay when you stay
$209 nightly
The price is $230 total per night from Nov 2 to Nov 3
$230 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free ...
9.2/10 Wonderful! (1,006 reviews)
"We visited Greenville for a wedding and our stay at the Westin was perfect!"

Reviewed on Sep 12, 2025

Opens in a new windowThe Westin Poinsett Greenville
Hyatt Regency Greenville

Hyatt Regency Greenville

220 N Main St, Greenville, SC
Fully refundableReserve now, pay when you stay
$166 nightly
The price is $182 total per night from Oct 12 to Oct 13
$182 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.6/10 Excellent! (1,000 reviews)
"The Hyatt was in the center of eveything that is going on. Staff was very kind and very helpfull and so many good restaurants in walking distance and well night life. Highly recommend staying at the Hyatt Regency!"

Reviewed on Sep 29, 2025

Opens in a new windowHyatt Regency Greenville
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

851 Congaree Rd, Greenville, SC
Fully refundable
$95 nightly
The price is $105 total per night from Oct 5 to Oct 6
$105 total
Oct 5 - Oct 6
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
8.4/10 Very Good! (1,007 reviews)
"Check in was very smooth and staff were very friendly. The room was nice bed was comfortable. We had a wonderful dinner in the Ruth Chris restaurant!"

Reviewed on Sep 29, 2025

Opens in a new windowCrowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Hilton Greenville

Hilton Greenville

45 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $114 total per night from Oct 5 to Oct 6
$114 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, ...
8/10 Very Good! (1,000 reviews)
"Very nice"

Reviewed on Sep 30, 2025

Opens in a new windowHilton Greenville
Sleep Inn at Greenville Convention Cente

Sleep Inn at Greenville Convention Cente

231 N Pleasantburg Dr, Greenville, SC
$89 nightly
The price is $98 total per night from Oct 5 to Oct 6
$98 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the business ...
7.8/10 Good! (1,010 reviews)
"Great location, clean rooms."

Reviewed on Sep 26, 2025

Opens in a new windowSleep Inn at Greenville Convention Cente
Best Western Travelers Rest Greenville

Best Western Travelers Rest Greenville

110 Hawkins Rd, Travelers Rest, SC
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $106 total per night from Oct 9 to Oct 10
$106 total
Oct 9 - Oct 10
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
7.6/10 Good! (1,002 reviews)
"Hotel is in the process of updates. If they continue, should be really nice soon. Fine right now, just some things quite dated."

Reviewed on Sep 18, 2025

Opens in a new windowBest Western Travelers Rest Greenville
La Quinta Inn & Suites by Wyndham Greenville Haywood

La Quinta Inn & Suites by Wyndham Greenville Haywood

65 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $73 total per night from Oct 5 to Oct 6
$73 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. ...
7.2/10 Good! (1,066 reviews)
"Clean room, nice staff, and convenient location."

Reviewed on Oct 1, 2025

Opens in a new windowLa Quinta Inn & Suites by Wyndham Greenville Haywood
Red Roof Inn Spartanburg – I-26

Red Roof Inn Spartanburg – I-26

6765 Pottery Rd, Spartanburg, SC
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $68 total per night from Oct 19 to Oct 20
$68 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free continental breakfast each morning. Staff at the 24-hour ...
6.8/10 (723 reviews)
"Just needed a place to sleep and this was perfect. Nothing fancy, just your basics. Was clean great price."

Reviewed on Sep 1, 2025

Opens in a new windowRed Roof Inn Spartanburg – I-26
Don't see what you're looking for?
See all available properties in Greenville - Spartanburg
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Greenville - Spartanburg

Greenville - Spartanburg Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Greenville - Spartanburg luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Greenville - Spartanburg to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Greenville - Spartanburg will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Greenville - Spartanburg, and plan your next opulent escape.


Greenville - Spartanburg hotels essential information

Accommodation
1,525 hotels
Lowest Price
$68
Highest Price
$230
Popular hotels
The Westin Poinsett Greenville, Hyatt Regency Greenville, Sleep Inn at Greenville Convention Cente, Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG, Red Roof Inn Spartanburg – I-26, La Quinta Inn & Suites by Wyndham Greenville Haywood, Hilton Greenville, Best Western Travelers Rest Greenville

Popular Luxury Stays in Greenville - Spartanburg

Recent Greenville - Spartanburg Hotel Reviews By Fellow Wanderers

Explore More Ways to Travel with Travelocity

Explore More Ways to Travel with Travelocity