Deals on vacations and trips to East Prairie

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East Prairie flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.
The Family Truckster

The Family Truckster

2 out of 5
Price was $565, price is now $536 per person
$536
per person
Feb 6 - Feb 9
found 1 day ago
Roundtrip flight included
Tampa (TPA) to Paducah (PAH)
This vacation home includes free WiFi in public areas and barbecue grills.
Salt & Pepper

Salt & Pepper

2 out of 5
Price was $947, price is now $883 per person
$883
per person
Feb 6 - Feb 9
found 1 day ago
Roundtrip flight included
Tampa (TPA) to Paducah (PAH)
Free WiFi in public areas is available at this vacation home.
Pepper's Place

Pepper's Place

2 out of 5
Price was $581, price is now $550 per person
$550
per person
Feb 6 - Feb 9
found 1 day ago
Roundtrip flight included
Tampa (TPA) to Paducah (PAH)
Free WiFi in public areas is available at this vacation home.
Captain's Quarters

Captain's Quarters

2 out of 5
Price was $566, price is now $537 per person
$537
per person
Feb 6 - Feb 9
found 1 day ago
Roundtrip flight included
Tampa (TPA) to Paducah (PAH)
Free WiFi in public areas is available at this vacation home.
Pine Grove Lane

Pine Grove Lane

2 out of 5
Price was $568, price is now $538 per person
$538
per person
Feb 6 - Feb 9
found 1 day ago
Roundtrip flight included
Tampa (TPA) to Paducah (PAH)
Free WiFi in public areas is available at this vacation home.

Top East Prairie hotels deals

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$90 nightly
The price is $103 total per night
$103 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.
Pool
Breakfast included
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$102 nightly
The price is $115 total per night
$115 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free continental breakfast, free WiFi, and free self parking. A 24-hour business center, a snack bar/deli, and express check-out are also on offer.
Pool
Breakfast included
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$80 nightly
The price is $91 total per night
$91 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A 24-hour business center, a grocery/convenience store, and express check-out are also on offer.
Pool
Breakfast included
Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America

2.5 out of 5
1111 BLue Heron Lane Union City TN
Free Cancellation
$80 nightly
The price is $95 total per night
$95 total
Jan 6 - Jan 7, 2026
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$75 nightly
The price is $86 total per night
$86 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free daily breakfast.
Pool
Hot Tub
Hospitality House Union City I 69 / US 51

Hospitality House Union City I 69 / US 51

2.5 out of 5
1221 W Reelfoot Ave Union City TN
Free Cancellation
Reserve now, pay when you stay
$54 nightly
The price is $65 total per night
$65 total
Jan 29 - Jan 30, 2026
Total with taxes and fees
A restaurant and a seasonal outdoor pool are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Big Oak Tree State Park

4.5/5(3 reviews)

You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.

Big Oak Tree State Park

Frequently asked questions

How much are vacation packages to East Prairie?
Starting as low as $536, flight and hotel packages are a great way to make your travel budget stretch further. East Prairie, here you come!
Where can I get the best vacation package deals for East Prairie?
You can pick up sensational East Prairie package deals with Travelocity. Select from 400 air carriers and 1,000,000 worldwide properties and turn those travel fantasies into reality.
Why should I purchase my East Prairie vacation bundle with Travelocity?
The three S's — savings, support and a stress-free booking — are just the beginning. Enjoy a fulfilling travel experience knowing you have access to our team of customer support experts around-the-clock. With the Travelocity Price Match Guarantee, you can rest easy knowing you're getting the best deal available.
Can I save on my East Prairie car rental if I book it with my hotel or flight?
You certainly can — combine your car, flight and hotel into an East Prairie vacation package and you'll save tons. With so much to see in the East Prairie area, that rental vehicle will more than come in handy. Once you've settled into the driver's seat, crank up the tunes and make your way to Orpheum Theatre, a well-known attraction roughly 120 mi from East Prairie.
Which airport is best for East Prairie?
Cape Girardeau Municipal Airport (CGI) is where many vacationers arrive. It's situated 30 mi north from inner East Prairie. Alternatively, check out the deals to Barkley Regional Airport (PAH), which is 40 mi away from central East Prairie.
Where should I stay when visiting East Prairie?
If you're searching for somewhere to spend your nights, take a look at the New ground level unit with Huge Outdoor Space. It's the top choice for many travelers.

Photos of local treasures

Browse East Prairie vacation photos for more inspiration