Cheap Flights to Santa Cruz from $108 (2026/2027)
Wander Wisely with exceptional service, 24/7 supportOpens in a new window
Feel at ease with free flight cancellations within 24 hours of booking
Change your flight without a fee on select flights
Jet to one of Santa Cruz's top cities
Puerto Ayora
Flights
Santa Rosa
Flights
How Much Does it Cost To Fly To Santa Cruz?
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.
GYE
Jose Joaquin de Olmedo Intl.
SCY
San Cristobal
$252 Roundtrip, found 1 day ago
$252
Roundtrip
found 1 day ago
GYE
Jose Joaquin de Olmedo Intl.
SCY
San Cristobal
$263 Roundtrip, found 1 day ago
$263
Roundtrip
found 1 day ago
UIO
Mariscal Sucre Intl.
SCY
San Cristobal
$314 Roundtrip, found 1 hour ago
$314
Roundtrip
found 1 hour ago
GYE
Jose Joaquin de Olmedo Intl.
GPS
Seymour
$320 Roundtrip, found 9 hours ago
$320
Roundtrip
found 9 hours ago
UIO
Mariscal Sucre Intl.
GPS
Seymour
$347 Roundtrip, found 6 hours ago
$347
Roundtrip
found 6 hours ago
MIA
Miami Intl.
SCY
San Cristobal
$521 Roundtrip, just found
$521
Roundtrip
just found
BOS
Logan Intl.
SCY
San Cristobal
$549 Roundtrip, found 17 hours ago
$549
Roundtrip
found 17 hours ago
MIA
Miami Intl.
GPS
Seymour
$554 Roundtrip, found 3 hours ago
$554
Roundtrip
found 3 hours ago
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| GYE | Puerto Baquerizo Moreno | November 19 to November 23 | $255 |
| GYE | Santa Rosa | October 26 to October 28 | $320 |
| UIO | Santa Rosa | October 16 to October 23 | $347 |
| LIM | Puerto Baquerizo Moreno | November 20 to November 23 | $489 |
| MIA | Puerto Baquerizo Moreno | September 4 to September 14 | $521 |
| LIM | Santa Rosa | September 19 to September 23 | $527 |
| YYZ | Puerto Baquerizo Moreno | November 4 to November 8 | $661 |
| YYZ | Santa Rosa | November 20 to November 24 | $696 |
| JFK | Santa Rosa | September 11 to September 19 | $724 |
| LAX | Santa Rosa | September 16 to September 23 | $814 |
| IAH | Puerto Baquerizo Moreno | September 23 to September 28 | $991 |
| IAH | Santa Rosa | September 14 to September 28 | $1,024 |
| ATL | Puerto Baquerizo Moreno | October 5 to October 11 | $1,071 |
| ATL | Santa Rosa | October 20 to October 25 | $1,103 |
| LAX | Puerto Baquerizo Moreno | September 18 to September 24 | $1,219 |
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| GYE | Puerto Baquerizo Moreno | August 29 to September 6 | $298 |
| UIO | Puerto Baquerizo Moreno | August 29 to September 3 | $318 |
| GYE | Santa Rosa | August 30 to September 4 | $350 |
| UIO | Santa Rosa | August 30 to September 2 | $398 |
| MIA | Puerto Baquerizo Moreno | August 29 to September 2 | $521 |
| MIA | Santa Rosa | August 29 to September 2 | $554 |
| LIM | Santa Rosa | August 29 to August 31 | $570 |
| JFK | Puerto Baquerizo Moreno | August 29 to September 7 | $691 |
| JFK | Santa Rosa | August 29 to September 7 | $724 |
| ATL | Puerto Baquerizo Moreno | August 29 to September 7 | $1,171 |
| LAX | Santa Rosa | August 28 to September 6 | $1,189 |
| ATL | Santa Rosa | August 30 to September 3 | $1,401 |
| LAX | Puerto Baquerizo Moreno | August 28 to September 6 | $1,547 |
| IAH | Santa Rosa | August 28 to September 3 | $1,547 |
Best Santa Cruz Flight and Hotel Packages
Price found within the past 48 hours. Click for updated prices.
Travelers ❤️ These Santa Cruz 🏨
Hotel Fiesta
Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos
Stay at this hotel in Puerto Ayora. Enjoy free WiFi, 3 hot tubs, and room service. Our guests praise the helpful staff in our reviews. Popular attractions Las Ninfas Lagoon and Malecon are located nearby.
9/10 Wonderful! (430 reviews)
"Stayed for 4 nights, the staff were very friendly and helped us with all our questions and requests. The room was clean and well air conditioned, and there was a fantastic pool and jacuzzis. Everything is in very close walking distance from the hotel. Price was good, and I would definitely recommend ..."
Reviewed on Aug 11, 2026
Finch Bay Galapagos Hotel
Barrio Punta Estrada Puerto Ayora Galapagos
Book a stay at this luxury hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a full-service spa. Popular attractions Playa de los Alemanes and Malecon are located nearby.
9.4/10 Exceptional! (103 reviews)
"Wonderful staff and great facility!"
Reviewed on Aug 15, 2026
Maidith Galapagos Inn
Calle Cucuve #341 y Seymour, Santa Cruz Puerto Ayora Galápagos
Book a stay at this family-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Fishing Piers and Gus Angermeyer Ferry Terminal are located nearby.
10/10 Exceptional! (157 reviews)
"Pros: quiet location but still a close walk to town, excellent rotating breakfast options, warm pool for the kids to play in, very clean and comfortable, lots of character! Cons: none, we loved it all!"
Reviewed on Aug 13, 2026
Save an average of 15% on thousands of hotels when you're signed in
Hotel el descanso del Guia
Calle Delfin, Barrio el Mirador Puerto Ayora Galapagos
Book a stay at this family-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular attractions Las Ninfas Lagoon and Fishing Piers are located nearby.
8.8/10 Excellent! (228 reviews)
"Really quirky hotel which we loved. Very central and staff were great."
Reviewed on Aug 14, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.