Cheap Flights to Mississippi County from $89 (2026/2027)

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The Mississippi River near Hannibal, Missouri, USA

East Prairie

Flights
East Prairie

How Much Does it Cost To Fly To Mississippi County?

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Thu, Jun 25 - Sun, Jun 28
ORD
O'Hare Intl.
CGI
Cape Girardeau Municipal
$178 Roundtrip, found 12 hours ago
$178
Roundtrip
found 12 hours ago
Select Contour Airlines flight, departing Thu, Jun 25 from O'Hare Intl. to Cape Girardeau Municipal, returning Sun, Jun 28, priced at $178 found 12 hours ago
Sat, Aug 1 - Wed, Aug 5
ORD
O'Hare Intl.
PAH
Barkley Regional
$194 Roundtrip, found 1 day ago
$194
Roundtrip
found 1 day ago
Select United flight, departing Sat, Aug 1 from O'Hare Intl. to Barkley Regional, returning Wed, Aug 5, priced at $194 found 1 day ago
Thu, Aug 27 - Mon, Aug 31
DFW
Dallas-Fort Worth Intl.
CGI
Cape Girardeau Municipal
$218 Roundtrip, found 2 days ago
$218
Roundtrip
found 2 days ago
Select Contour Airlines flight, departing Thu, Aug 27 from Dallas-Fort Worth Intl. to Cape Girardeau Municipal, returning Mon, Aug 31, priced at $218 found 2 days ago
Tue, Jun 9 - Tue, Jun 16
LGA
LaGuardia
PAH
Barkley Regional
$328 Roundtrip, found 14 hours ago
$328
Roundtrip
found 14 hours ago
Select United flight, departing Tue, Jun 9 from LaGuardia to Barkley Regional, returning Tue, Jun 16, priced at $328 found 14 hours ago
Tue, Jun 9 - Tue, Jun 16
EWR
Newark Liberty Intl. Airport
PAH
Barkley Regional
$340 Roundtrip, found 14 hours ago
$340
Roundtrip
found 14 hours ago
Select United flight, departing Tue, Jun 9 from Newark Liberty Intl. Airport to Barkley Regional, returning Tue, Jun 16, priced at $340 found 14 hours ago
Tue, Jun 9 - Tue, Jun 16
EWR
Newark Liberty Intl. Airport
PAH
Barkley Regional
$345 Roundtrip, found 14 hours ago
$345
Roundtrip
found 14 hours ago
Select United flight, departing Tue, Jun 9 from Newark Liberty Intl. Airport to Barkley Regional, returning Tue, Jun 16, priced at $345 found 14 hours ago
Thu, Jun 4 - Mon, Jun 8
OKC
Will Rogers World
PAH
Barkley Regional
$367 Roundtrip, found 1 day ago
$367
Roundtrip
found 1 day ago
Select United flight, departing Thu, Jun 4 from Will Rogers World to Barkley Regional, returning Mon, Jun 8, priced at $367 found 1 day ago
Fri, Aug 7 - Mon, Aug 10
CLT
Charlotte-Douglas Intl.
PAH
Barkley Regional
$370 Roundtrip, found 22 hours ago
$370
Roundtrip
found 22 hours ago
Select United flight, departing Fri, Aug 7 from Charlotte-Douglas Intl. to Barkley Regional, returning Mon, Aug 10, priced at $370 found 22 hours ago
Fri, Aug 7 - Mon, Aug 10
CLT
Charlotte-Douglas Intl.
PAH
Barkley Regional
$372 Roundtrip, found 22 hours ago
$372
Roundtrip
found 22 hours ago
Select United flight, departing Fri, Aug 7 from Charlotte-Douglas Intl. to Barkley Regional, returning Mon, Aug 10, priced at $372 found 22 hours ago
Tue, Jun 9 - Tue, Jun 16
EWR
Newark Liberty Intl. Airport
PAH
Barkley Regional
$394 Roundtrip, found 14 hours ago
$394
Roundtrip
found 14 hours ago
Select United flight, departing Tue, Jun 9 from Newark Liberty Intl. Airport to Barkley Regional, returning Tue, Jun 16, priced at $394 found 14 hours ago
Thu, Jun 4 - Mon, Jun 8
OKC
Will Rogers World
PAH
Barkley Regional
$398 Roundtrip, found 20 hours ago
$398
Roundtrip
found 20 hours ago
Select United flight, departing Thu, Jun 4 from Will Rogers World to Barkley Regional, returning Mon, Jun 8, priced at $398 found 20 hours ago
OriginDestinationTravel DatesFlights From*
ORDScott CityJune 11 to June 15$178
ORDScott CityJune 11 to June 15$178
ORDWest PaducahAugust 1 to August 5$194
ORDWest PaducahAugust 1 to August 5$194
MCOWest PaducahJune 22 to June 29$301
SATWest PaducahJune 23 to June 26$534
MCOScott CityJuly 16 to July 19$1,229
*Prices include taxes and fees

Best Mississippi County Flight and Hotel Packages

Price found within the past 48 hours. Click for updated prices.
La Quinta Inn & Suites by Wyndham Paducah
3.0-star property

La Quinta Inn & Suites by Wyndham Paducah

Jul 16 - Jul 20

4 night stay

Washington (WAS) to Paducah (PAH)

United • Non-stop roundtrip • Coach
Price was $612, price is now $554 per person
$554
per person
found 9 hours ago
Belle Louise Historic Guest House
3.5-star property

Belle Louise Historic Guest House

Jul 16 - Jul 20

4 night stay

Washington (WAS) to Paducah (PAH)

United • Non-stop roundtrip • Coach
Price was $1,061, price is now $908 per person
$908
per person
found 9 hours ago
The Respite Bed and Breakfast
4.5-star property

The Respite Bed and Breakfast

Jul 16 - Jul 20

4 night stay

Washington (WAS) to Paducah (PAH)

United • Non-stop roundtrip • Coach
Price was $670, price is now $600 per person
$600
per person
found 9 hours ago
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Travelers ❤️ These Mississippi County 🏨

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2 out of 5
310 S Story St Charleston MO
Stay at this motel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews.
6.6/10 (635 reviews)
"Windows were taped over. Hall and linens smelled dusty. No glaaes, cups or coffee pot or coffee."

Reviewed on May 24, 2026

Opens in a new windowSuper 8 by Wyndham Charleston/Sikeston East MO
The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston

2.5 out of 5
102 Drake St Charleston MO
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our reviews.
6.8/10 (412 reviews)
"Coffee"

Reviewed on Apr 22, 2026

Opens in a new windowThe Riverstone Hotel Charleston-Sikeston
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Central Park and Sikeston Depot Museum are located nearby.
9.6/10 Exceptional! (1,000 reviews)
"Very nice clean room. Staff was very nice."

Reviewed on May 24, 2026

Opens in a new windowDrury Inn & Suites Sikeston, MO
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Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central Park and Sikeston Depot Museum are located nearby.
9/10 Wonderful! (566 reviews)
"Ok stay"

Reviewed on May 24, 2026

Opens in a new windowHampton Inn Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much is the cheapest flight to Mississippi County?
Within the last seven days, the cheapest roundtrip flight to Mississippi County cost $178 on our site. Search through our unbeatable deals, make a booking and prepare for your next getaway. This price was available on Travelocity for flights to Mississippi County departing within the next year. Prices and availability are subject to change. Additional terms apply.
What is the cheapest month to fly to Mississippi County?
June is the cheapest month to jet to Mississippi County based on Travelocity's direct return flight demand between January and December last year. We'll help you bag an incredible deal so you can start preparing your itinerary today.
How can I check my flight status to Mississippi County?
Whether you'd like to view the status of your flight to Mississippi County or make changes to your itinerary, you'll find all the necessary details on our customer portal, Trips. Click on "Trips" at the top of our homepage, then sign in or create an account. Another convenient way to view and manage all your bookings is with the Travelocity app. Get real-time advice like flight status alerts and quickly share updates with any family flying with you.
How do I find the best deals on flights to Mississippi County?
There are a few ways — book in advance, avoid peak season and be flexible with your travel dates. If your dates aren't set in stone, search for your flight to Mississippi County on Travelocity and click on "Flexible dates" at the top of the page. This will help you locate any cheaper tickets on a nearby day. $178 was the lowest price paid for a roundtrip flight to Mississippi County in the last seven days. This price was available on Travelocity for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
Why should I book my flight to Mississippi County with Travelocity?
Pack your suitcase and get set for an epic trip with Travelocity. We'll help you find great deals on cheap flights to Mississippi County. Whether you're looking for flexible airfares with plenty of room to move or cheap family flights on low-cost airlines, we've got what you need.
What are the most popular flight routes to Mississippi County?
If you have plans to jump on a flight to Mississippi County, here are some leading routes to look into:

  • Chicago, IL (ORD-O'Hare Intl.) to Nashville Intl. Airport (BNA) - 2,491 flights a month.
  • Atlanta, GA (ATL-Hartsfield-Jackson Atlanta Intl.) to Nashville Intl. Airport (BNA) - 1,932 flights a month.
  • New York, NY (LGA-LaGuardia) to Nashville Intl. Airport (BNA) - 1,911 flights a month.

How much is a flight to Mississippi County on average?
Travelers have booked roundtrip flights to Mississippi County for between $178 and $1,229 with Travelocity in the last seven days. Whether you'd like to fly budget or first class, we'll help you get your hands on an awesome deal. These prices were available on Travelocity for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
How long is the average flight to Mississippi County?
To get a feel for the average time of a direct flight to Mississippi County, take a peek at these popular routes:

  • Chicago, IL (ORD-O'Hare Intl.) to Nashville Intl. Airport (BNA) - 1 hour and 34 minutes
  • Atlanta, GA (ATL-Hartsfield-Jackson Atlanta Intl.) to Nashville Intl. Airport (BNA) - 1 hour and 5 minutes
  • New York, NY (LGA-LaGuardia) to Nashville Intl. Airport (BNA) - 2 hours and 26 minutes

What can I expect on a flight to Mississippi County?
How long your flight takes and whether you go with a low-priced or full-service carrier will largely determine this. If you're seeking long-haul flights to Mississippi County, drinks, food and entertainment are routine inclusions. After cheap flights for family vacations? Look up the fares from low-cost carriers. These airlines typically don't provide as many inclusions, so be prepared to pay for your drinks and meals.