Explore top 2025 4 Star Hotels in St. Ann
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Top St. Ann 4 Star hotels
Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $138 total per night from Nov 28 to Nov 29
$138 total
Nov 28 - Nov 29
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
8.4/10 Very Good! (1,038 reviews)
I didn’t eat breakfast
Reviewed on Nov 11, 2025
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $120 total per night from Nov 23 to Nov 24
$120 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
8.6/10 Excellent! (1,096 reviews)
Parking was a mess and super expensive
Reviewed on Nov 14, 2025
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $129 total per night from Dec 12 to Dec 13
$129 total
Dec 12 - Dec 13
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
8.4/10 Very Good! (3,998 reviews)
Nice hotel close to the arch. Ruth steakhouse is right inside hotel. Staff pleasant
Reviewed on Nov 15, 2025
Hilton St. Louis Frontenac
1335 S Lindbergh Blvd Frontenac MO
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $161 total per night from Nov 23 to Nov 24
$161 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.6/10 Excellent! (1,005 reviews)
All was well
Reviewed on Nov 15, 2025
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
3550 Samuel Sheppard Drive St. Louis MO
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $141 total per night from Nov 21 to Nov 22
$141 total
Nov 21 - Nov 22
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. ...
8.8/10 Excellent! (1,022 reviews)
Probably one of the coolest hotels I’ve ever stayed at. Me and my 3 teenage girls had a blast at the fox and then at this hotel
Reviewed on Nov 13, 2025
The Cheshire
6300 Clayton Rd Richmond Heights MO
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $152 total per night from Nov 27 to Nov 28
$152 total
Nov 27 - Nov 28
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
8.4/10 Very Good! (1,002 reviews)
Great stay! The room could have been a tiny bit cleaner but nothing crazy! Mainly stains on the table and some dusty areas but beds and bathrooms were clean! The staff was super nice and the place was nicely decorated.
Reviewed on Nov 15, 2025
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$156 nightly
The price is $183 total per night from Nov 22 to Nov 23
$183 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9/10 Wonderful! (1,458 reviews)
Great vibes
Reviewed on Nov 14, 2025
Live by Loews - St.Louis
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $177 total per night from Nov 20 to Nov 21
$177 total
Nov 20 - Nov 21
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
9.2/10 Wonderful! (1,075 reviews)
We had an amazing view of the ballpark! The room and service was great. The restaurant and food room service were delicious! Overall great stay!
Reviewed on Nov 12, 2025
The Westin St. Louis
811 Spruce St St. Louis MO
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $138 total per night from Nov 22 to Nov 23
$138 total
Nov 22 - Nov 23
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...
8.4/10 Very Good! (1,000 reviews)
Very polite staff and very clean
Reviewed on Nov 11, 2025
Ameristar Casino Resort and Spa
1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
$166 nightly
The price is $194 total per night from Dec 7 to Dec 8
$194 total
Dec 7 - Dec 8
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside ...
8.4/10 Very Good! (1,000 reviews)
My favorite
Reviewed on Nov 10, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
4 Star Hotels St. Ann
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in St. Ann 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in St. Ann will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in St. Ann, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent St. Ann hotel reviews by fellow wanderers
21C Museum Hotel St Louis
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Great vibes"
A verified traveler stayed at 21C Museum Hotel St Louis
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