Explore 32 Luxury Hotels in Tenderloin

Name: The Clift Royal Sonesta San Francisco
Price range: $250 total

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Best Luxury Hotels in Tenderloin

Hotel Nikko San Francisco

222 Mason St San Francisco CA

Fully refundableReserve now, pay when you stay

$217 nightly

$255 total

Nov 20 - Nov 21

Total with taxes and fees

A nightclub, 2 restaurants, and an indoor pool are all featured at this luxury hotel. Enjoy the gym and perks like free WiFi. You'll appreciate the a rooftop ...

9.4/10 Exceptional! (3,171 reviews)

"I had a wonderful stay her with my family. The staff was attentive, Elevators spacious. The vaulted glass enclosure for the pool area was beautiful, relaxing and quiet. There pet area was very nice too. Yes, I would recommend a staycation or weekend getaway here. Valet parking is worth it ; Downtown ..."

Reviewed on Oct 27, 2026

Handlery Union Square Hotel

351 Geary St San Francisco CA

Fully refundableReserve now, pay when you stay

$149 nightly

$176 total

Nov 21 - Nov 22

Total with taxes and fees

This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. ...

8.8/10 Excellent! (3,693 reviews)

"This hotel is our go-to when we stay in the city. Most recent trip, we were given a balcony room. I highly recommend these rooms. We spent a good portion of our stay just taking in the city."

Reviewed on Oct 26, 2026

Hotel Spero, Vignette Collection by IHG

405 Taylor St San Francisco CA

Fully refundable

$144 nightly

$169 total

Nov 22 - Nov 23

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, 24-hour business center, ...

8.6/10 Excellent! (1,155 reviews)

"Super nice staff, clean and cozy"

Reviewed on Oct 27, 2026

Staypineapple, An Elegant Hotel, Union Square

580 Geary St San Francisco CA

Fully refundableReserve now, pay when you stay

$145 nightly

$171 total

Nov 27 - Nov 28

Total with taxes and fees

This hotel features luggage storage, a safe deposit box, and concierge services. If you want to take your pet along, this pet-friendly property offers everything ...

8.6/10 Excellent! (1,000 reviews)

"The block this is on is rough. Inside is very nice looking but quite bare bones. Rooms are tiny but fairly comfortable. The air conditioner is loud and blows right onto the bed. Ours stopped working in the middle of the night and blinked a very bright light all night. It was hot and no top sheet ..."

Reviewed on Oct 25, 2026

Hotel Bijou - Union Square

111 Mason Street San Francisco CA

Fully refundableReserve now, pay when you stay

$126 nightly

$148 total

Nov 26 - Nov 27

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. A business center, luggage storage, and locker space are also on ...

7.4/10 Good! (1,004 reviews)

"They took USD 60 of my USD 100 deposit for absolutely no reason."

Reviewed on Oct 26, 2026

Monarch Hotel

1015 Geary St San Francisco CA

Free WiFi in public areas, luggage storage, and a safe deposit box are available at this hotel. The front desk is staffed around-the-clock and concierge services ...

6.2/10 (997 reviews)

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"Disappointed that they wouldn’t accommodate in any way due to covid. We would of wish to reschedule or have some options, instead of losing our money for something not our fault."

Reviewed on Aug 30, 2020

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Adante Hotel

610 Geary St San Francisco CA

This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Traveling on business? Take advantage of the laundry service ...

6.2/10 (997 reviews)

Cockroach

"It was all ok until my friend pointed out a very large cockroach dead on the bathroom floor"

Reviewed on Apr 26, 2020

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The Clift Royal Sonesta San Francisco

495 Geary St San Francisco CA

Fully refundableReserve now, pay when you stay

$212 nightly

$250 total

Nov 6 - Nov 7

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Tenderloin

Hotel Nikko San Francisco

222 Mason St San Francisco CA

$217 nightly

$255 total

Nov 20 - Nov 21

Total with taxes and fees

9.4/10 Exceptional! (3,171 reviews)

5 star hotels in Tenderloin

The Ritz-Carlton, San Francisco

600 Stockton St San Francisco CA

$472 nightly

$556 total

Nov 22 - Nov 23

Total with taxes and fees

9.4/10 Exceptional! (1,005 reviews)

Tenderloin Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Tenderloin luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Tenderloin to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Tenderloin will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Tenderloin, and plan your next opulent escape.

Tenderloin hotels essential information

Accommodation	4,221 hotels
Lowest Price	$120
Highest Price	$556
Popular hotels	The Clift Royal Sonesta San Francisco, Hotel Spero, Vignette Collection by IHG, Hotel Nikko San Francisco, Staypineapple, An Elegant Hotel, Union Square, Handlery Union Square Hotel, Monarch Hotel, Hotel Bijou - Union Square, Adante Hotel

Popular Luxury Stays in Tenderloin

Recent Tenderloin Hotel Reviews By Fellow Wanderers

Chancellor Hotel on Union Square

4 out of 5

Posted 1 hour ago

Travelocity Verified Review

"Fantastic location in San Francisco. Bed was comfortable. Bathroom very small, but sufficient, with good bathtub and shower. Upkeep of hotel could be better. The window in the bathroom was left partially open, and could not be shut, for example. Upkeep on this old historic hotel was less than ideal. However, the location is so good and the staff are so nice, with a good price, that I'll return. Next door to Sears Fine Foods, which is a SF legend and a must for breakfast. Across the street from Beacon Grand Hotel, which has a fantastic cocktail bar and great environment. If you are looking for luxury, then this is not your hotel. If you are looking for a solid hotel with good staff, great price and great location in San Francisco, this is very good."

A verified traveler stayed at Chancellor Hotel on Union Square