Explore 32 Luxury Hotels in Tenderloin

Name: Handlery Union Square Hotel
Price range: $191 total

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Best Luxury Hotels in Tenderloin

The Clift Royal Sonesta San Francisco

495 Geary St San Francisco CA

Fully refundableReserve now, pay when you stay

$203 nightly

$239 total

Oct 23 - Oct 24

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...

9.2/10 Wonderful! (1,533 reviews)

"I like the whole experience, but the check-in was a little wonky. I had already pre-paid the reservation on the phone and she kept saying it was declined at the check in. It wasn’t declined, and showed her on my bank statement. She gave me the keys and just said we”Ll figure it out in the morning. ..."

Reviewed on Sep 28, 2026

Hotel Spero, Vignette Collection by IHG

405 Taylor St San Francisco CA

Fully refundable

$165 nightly

$194 total

Oct 23 - Oct 24

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, 24-hour business center, ...

8.8/10 Excellent! (1,182 reviews)

"A nice room, location and lobby. Friendly staff. However, no coffee machine in room, and the lights switches didn't do anything. You had to turn each light on and off individually."

Reviewed on Sep 28, 2026

Staypineapple, An Elegant Hotel, Union Square

580 Geary St San Francisco CA

Fully refundableReserve now, pay when you stay

$160 nightly

$189 total

Oct 25 - Oct 26

Total with taxes and fees

This hotel features luggage storage, a safe deposit box, and concierge services. If you want to take your pet along, this pet-friendly property offers everything ...

8.6/10 Excellent! (1,006 reviews)

"A beautiful and well maintained space. Staff was warm and helpfull. The h"

Reviewed on Sep 28, 2026

Hotel Bijou - Union Square

111 Mason Street San Francisco CA

Fully refundableReserve now, pay when you stay

$115 nightly

$135 total

Oct 27 - Oct 28

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. A business center, luggage storage, and locker space are also on ...

7.4/10 Good! (979 reviews)

"Clean, comfortable, pretty noisy at night. In the “bad” part of town. I didn’t feel unsafe during the day. Good idea to avoid walking around town at night. Great restaurant with exceptional food & ambiance. Wonderful staff."

Reviewed on Sep 27, 2026

Monarch Hotel

1015 Geary St San Francisco CA

Free WiFi in public areas, luggage storage, and a safe deposit box are available at this hotel. The front desk is staffed around-the-clock and concierge services ...

6.2/10 (997 reviews)

isapp

"Disappointed that they wouldn’t accommodate in any way due to covid. We would of wish to reschedule or have some options, instead of losing our money for something not our fault."

Reviewed on Aug 30, 2020

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Adante Hotel

610 Geary St San Francisco CA

This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Traveling on business? Take advantage of the laundry service ...

6.2/10 (997 reviews)

Cockroach

"It was all ok until my friend pointed out a very large cockroach dead on the bathroom floor"

Reviewed on Apr 26, 2020

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Hotel Nikko San Francisco

222 Mason St San Francisco CA

Fully refundableReserve now, pay when you stay

$234 nightly

$275 total

Oct 16 - Oct 17

Total with taxes and fees

A nightclub, 2 restaurants, and an indoor pool are all featured at this luxury hotel. Enjoy the gym and perks like free WiFi. You'll appreciate the a rooftop ...

Handlery Union Square Hotel

351 Geary St San Francisco CA

Fully refundableReserve now, pay when you stay

$162 nightly

$191 total

Oct 11 - Oct 12

Total with taxes and fees

This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Tenderloin

LUMA Hotel San Francisco

100 Channel Street San Francisco CA

$255 nightly

$300 total

Oct 2 - Oct 3

Total with taxes and fees

9.6/10 Exceptional! (2,629 reviews)

5 star hotels in Tenderloin

Taj Campton Place

340 Stockton St San Francisco CA

$246 nightly

$289 total

Oct 4 - Oct 5

Total with taxes and fees

9.2/10 Wonderful! (1,001 reviews)

Tenderloin Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Tenderloin luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Tenderloin to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Tenderloin will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Tenderloin, and plan your next opulent escape.

Tenderloin hotels essential information

Accommodation	4,201 hotels
Lowest Price	$135
Highest Price	$581
Popular hotels	The Clift Royal Sonesta San Francisco, Hotel Spero, Vignette Collection by IHG, Hotel Nikko San Francisco, Staypineapple, An Elegant Hotel, Union Square, Handlery Union Square Hotel, Monarch Hotel, Hotel Bijou - Union Square, Adante Hotel