Explore 32 Luxury Hotels in Tenderloin

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Best Luxury Hotels in Tenderloin

Hotel Nikko San Francisco

222 Mason St San Francisco CA

Fully refundableReserve now, pay when you stay

$217 nightly

$255 total

Feb 16 - Feb 17

Total with taxes and fees

A nightclub, 2 restaurants, and an indoor pool are all featured at this luxury hotel. Enjoy the gym and perks like free WiFi. You'll appreciate the a rooftop ...

9.2/10 Wonderful! (2,694 reviews)

Check-in process was excellent

Reviewed on Jan 21, 2026

The Clift Royal Sonesta San Francisco

495 Geary St San Francisco CA

Fully refundableReserve now, pay when you stay

$182 nightly

$214 total

Feb 15 - Feb 16

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...

9/10 Wonderful! (1,386 reviews)

Perfect location Great staff Very clean

Reviewed on Jan 19, 2026

Hotel Spero, Vignette Collection by IHG

405 Taylor St San Francisco CA

Fully refundableReserve now, pay when you stay

$127 nightly

$149 total

Jan 30 - Jan 31

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, 24-hour business center, ...

8.8/10 Excellent! (1,277 reviews)

The hotel is very nice, the area around the hotel is not.

Reviewed on Jan 22, 2026

Handlery Union Square Hotel

351 Geary St San Francisco CA

Fully refundableReserve now, pay when you stay

$132 nightly

$155 total

Jan 31 - Feb 1

Total with taxes and fees

This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. ...

8.8/10 Excellent! (2,826 reviews)

Clean, nice staff.

Reviewed on Jan 18, 2026

Staypineapple, An Elegant Hotel, Union Square

580 Geary St San Francisco CA

Fully refundableReserve now, pay when you stay

$120 nightly

$141 total

Jan 25 - Jan 26

Total with taxes and fees

This hotel features luggage storage, a safe deposit box, and concierge services. If you want to take your pet along, this pet-friendly property offers everything ...

8.6/10 Excellent! (1,001 reviews)

You gotta love the pineapple! They carried the female out well, was very charming

Reviewed on Jan 14, 2026

Hotel Bijou

111 Mason Street San Francisco CA

Fully refundableReserve now, pay when you stay

$114 nightly

$135 total

Feb 21 - Feb 22

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. A business center, luggage storage, and locker space are also on ...

7.4/10 Good! (867 reviews)

Staff was pleasant. Had issues with room access. Had to go to front desk multiple time to be let into room at different occasions. Also noise from people outside was excessive.

Reviewed on Jan 20, 2026

Monarch Hotel

1015 Geary St San Francisco CA

Free WiFi in public areas, luggage storage, and a safe deposit box are available at this hotel. The front desk is staffed around-the-clock and concierge services ...

isapp

Disappointed that they wouldn’t accommodate in any way due to covid. We would of wish to reschedule or have some options, instead of losing our money for something not our fault.

Reviewed on Aug 30, 2020

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Adante Hotel

610 Geary St San Francisco CA

This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Traveling on business? Take advantage of the laundry service ...

Cockroach

It was all ok until my friend pointed out a very large cockroach dead on the bathroom floor

Reviewed on Apr 26, 2020

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More 4 star hotels in Tenderloin

citizenM San Francisco Union Square

72 Ellis Street San Francisco CA

$134 nightly

$158 total

Jan 31 - Feb 1

Total with taxes and fees

9.4/10 Exceptional! (1,447 reviews)

5 star hotels in Tenderloin

Four Seasons Hotel San Francisco

757 Market St San Francisco CA

$395 nightly

$465 total

Jan 23 - Jan 24

Total with taxes and fees

9.4/10 Exceptional! (998 reviews)

Tenderloin Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Tenderloin luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Tenderloin to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Tenderloin will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Tenderloin, and plan your next opulent escape.

Tenderloin hotels essential information

Accommodation	4,761 hotels
Lowest Price	$130
Highest Price	$507
Popular hotels	The Clift Royal Sonesta San Francisco, Hotel Spero, Vignette Collection by IHG, Hotel Nikko San Francisco, Staypineapple, An Elegant Hotel, Union Square, Handlery Union Square Hotel, Monarch Hotel, Hotel Bijou, Adante Hotel