Book Kid-Friendly Hotels in Southeast Missouri from $63

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Top Southeast Missouri Kid Friendly Hotels

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $128 total per night from Aug 15 to Aug 16
$128 total
Aug 15 - Aug 16
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
9.6/10 Exceptional! (1,009 reviews)
"Great stay!"

Reviewed on Aug 10, 2026

Opens in a new windowDrury Inn & Suites Sikeston, MO
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3303 Campster Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Aug 16 to Aug 17
$102 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
9.4/10 Exceptional! (1,008 reviews)
"Everything was awesome, highly recommended this hotel"

Reviewed on Aug 7, 2026

Opens in a new windowDrury Inn & Suites Cape Girardeau
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO
Fully refundable
$110 nightly
The price is $124 total per night from Aug 16 to Aug 17
$124 total
Aug 16 - Aug 17
Total with taxes and fees
A full-service spa and an indoor pool are featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public ...
9.4/10 Exceptional! (1,008 reviews)
"Very nice hotel and staff. Would definitely recommend"

Reviewed on Aug 9, 2026

Opens in a new windowHoliday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville

1317 E Highway 84 Hayti MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $112 total per night from Aug 16 to Aug 17
$112 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
9.2/10 Wonderful! (1,005 reviews)
"Was very disappointed with the room….i moved to 3 different rooms because of the conditions of the rooms …I was home for my aunts funeral and I wasn’t very happy with my stay I was told by the manager that he emailed you all for a refund"

Reviewed on Aug 10, 2026

Opens in a new windowDrury Inn & Suites Hayti Caruthersville
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

120 S Interstate Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $108 total per night from Aug 16 to Aug 17
$108 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A 24-hour ...
Opens in a new windowBest Western Plus Sikeston I-55
Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

2904 Old Orchard Rd Jackson MO
Fully refundable
$80 nightly
The price is $87 total per night from Sep 8 to Sep 9
$87 total
Sep 8 - Sep 9
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Opens in a new windowComfort Suites Jackson-Cape Girardeau
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

1802 Gamel Cemetery Road Festus MO
Fully refundable
$110 nightly
The price is $126 total per night from Aug 16 to Aug 17
$126 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Opens in a new windowHoliday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

225 Drury Lane Jackson MO
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $85 total per night from Aug 23 to Aug 24
$85 total
Aug 23 - Aug 24
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Opens in a new windowDrury Inn & Suites Jackson MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels With Pools in Southeast Missouri

Southeast Missouri Kid-Friendly Hotels

It’s not a family vacation if you can’t bring the entire clan with you, is it? Next time you have a few days off from work, plan a family-friendly getaway.  Set off on an adventure the entire family will love, and book your stay at one of the kid-friendly hotels in Southeast Missouri.

Your little ones are the most important thing in your life, so make sure they enjoy your accommodation as much as you do. From a kids-only room service menu (macaroni and cheese, anyone?) to special perks like in-room video game consoles, these lodgings provide a little something extra for the smaller members of your crew. The best family-friendly hotels in Southeast Missouri may even offer playgrounds and other activities to keep the kiddos busy. What’s more, some hotels provide a babysitting service so you can get a few hours to yourself!

Whether you’re traveling with one small child or hauling around your entire extended family, Travelocity is here to help. Let us hook you up with hotels for kids in Southeast Missouri that will keep your youngsters happy without breaking the bank. You can save even more when you bundle your flight and hotel together, so what are you waiting for? Grab your family and get ready to explore!

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Recent Southeast Missouri Hotel Reviews By Fellow Wanderers