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Top hotels in Mission Valley East

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
$237 nightly
The price is $274 total per night from Apr 5 to Apr 6
$274 total
Apr 5 - Apr 6
Total with taxes and fees
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free ...
Perfect location for a fun time.

Reviewed on Mar 14, 2026

Opens in a new windowHard Rock Hotel San Diego
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $150 total per night from Apr 5 to Apr 6
$150 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
We had to go back to the lobby

Reviewed on Mar 15, 2026

Opens in a new windowThe DEXTRO Little Italy, BW Premier Collection
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
$245 nightly
The price is $281 total per night from Apr 5 to Apr 6
$281 total
Apr 5 - Apr 6
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 2 restaurants. Family-friendly amenities include mini golf and kid-friendly dining, along with ...
The room was clean but mixed with some things new and other things old. Never had hot water for the shower however the shower was large. Our view was awesome loved watching all the sailboats, skiers, row boats, kayaks etc. We even seen a purpose. People with dogs let them poo without picking up not ...

Reviewed on Mar 12, 2026

Opens in a new windowParadise Point Resort & Spa
DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

4 out of 5
7450 Hazard Center Dr San Diego CA
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $131 total per night from Apr 5 to Apr 6
$131 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 20 conference rooms, free WiFi in public areas, ...
Nice room, only downside was wifi was not connecting at all. Had called front desk, created an account because they said it was mandatory to even connect to the FREE wifi.

Reviewed on Mar 14, 2026

Opens in a new windowDoubleTree by Hilton Hotel San Diego - Mission Valley
Homewood Suites by Hilton San Diego Mission Valley/Zoo

Homewood Suites by Hilton San Diego Mission Valley/Zoo

3 out of 5
445 Camino Del Rio South San Diego CA
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $194 total per night from Apr 5 to Apr 6
$194 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Great location, restaurants, shops, fast food, stores, right across the hotel. Quick drive to zoo, La Jolla, old downtown San Diego… perfect location for those bucket lists. Front desk Gloria was a gem. Sweet, informative, and quick check in considering how late we arrived. We stayed in the queen ...

Reviewed on Mar 6, 2026

Opens in a new windowHomewood Suites by Hilton San Diego Mission Valley/Zoo
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $126 total per night from Apr 13 to Apr 14
$126 total
Apr 13 - Apr 14
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
Excellent experience

Reviewed on Mar 15, 2026

Opens in a new windowHandlery Hotel
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S San Diego CA
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $151 total per night from Apr 5 to Apr 6
$151 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
The staff was friendly and welcoming the hotel itself is outdated and needs renovations.

Reviewed on Mar 15, 2026

Opens in a new windowHilton San Diego Mission Valley
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $123 total per night from Apr 5 to Apr 6
$123 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...
Great place to stay close to many restruants and places of interest in San Diego.

Reviewed on Mar 15, 2026

Opens in a new windowDays Inn by Wyndham San Diego Hotel Circle
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $84 total per night from Apr 1 to Apr 2
$84 total
Apr 1 - Apr 2
Total with taxes and fees
2 hot tubs, an outdoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi ...
When checking in on Thursday I asked for a late checkout on Saturday because I work Saturday morning and fly home that afternoon. Checkout was 11am. I get off work at 11am and work 10 minutes from this hotel. The person said to ask the morning of departure. Because I leave for work Saturday morning ...

Reviewed on Mar 14, 2026

Opens in a new windowBest Western Seven Seas
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mission Valley East Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Mission Valley East area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Mission Valley East to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Mission Valley East are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Mission Valley East hotel reviews by fellow wanderers

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