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Book Exclusive Louisiana, MO Vacation Packages

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Louisiana flight + hotel packages

Towneplace Suites By Marriott St Charles

Towneplace Suites By Marriott St Charles

2.5 out of 5
Save 100% on your flight$641

$453

per person
Jun 21 - Jun 27
Roundtrip flight included
Chicago (ORD) to St. Louis (STL)
This hotel features a 24-hour fitness center and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

5 out of 5
Downtown Clayton
$1,369

$1,129

per person
Jun 20 - Jun 25
Roundtrip flight included
Houston (IAH) to St. Louis (STL)
This smoke-free hotel features 2 restaurants, a bar/lounge, and a fitness center. Traveling on business? Take advantage of the 10 conference rooms, business center, and valet parking. Self parking, a coffee shop, and a lobby fireplace are also offered.
Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

3.5 out of 5
Downtown St. Louis
$1,130

$956

per person
Jun 20 - Jun 25
Roundtrip flight included
Houston (IAH) to St. Louis (STL)
This hotel features an indoor pool and a fitness center. Traveling on business? Take advantage of the 6 conference rooms, 24-hour business center, and valet parking. Enjoy the spa tub and free perks like cooked-to-order breakfast and WiFi in public areas.
Courtyard by Marriott St. Louis Downtown West

Courtyard by Marriott St. Louis Downtown West

3 out of 5
Downtown West
$885

$769

per person
Jun 24 - Jun 28
Roundtrip flight included
Philadelphia (PHL) to St. Louis (STL)
This hotel features a restaurant, a 24-hour fitness center, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Self parking, a coffee shop, and a garden are also offered.
Stoney Creek Hotel & Conference Center Columbia

Stoney Creek Hotel & Conference Center Columbia

2.5 out of 5
$460

$402

per person
Aug 5 - Aug 10
Roundtrip flight included
Orlando (MCO) to St. Louis (STL)
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the fitness center and perks like free self parking.

Top Louisiana hotels deals

River's Edge Motel

River's Edge Motel

2 out of 5
201 Mansion St, Louisiana, MO
Free Cancellation
Reserve now, pay when you stay
The price is $72 per night
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock assistance.
Quality Inn & Suites Hannibal

Quality Inn & Suites Hannibal

2.5 out of 5
120 Lindsey Drive, Hannibal, MO
Free Cancellation
Reserve now, pay when you stay
The price is $83 per night
This hotel features a poolside bar, a bar/lounge, and an indoor pool. Traveling on business? Take advantage of the 4 conference rooms, as well as the 24-hour business center and free WiFi in public areas. Enjoy the spa tub and free perks like buffet breakfast and free self parking.
Best Western On The River

Best Western On The River

2.5 out of 5
401 North 3rd Street, Hannibal, MO
Free Cancellation
Reserve now, pay when you stay
The price is $82 per night
This hotel features an indoor pool and a fitness center. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the seasonal outdoor pool and free perks like self-serve breakfast and free self parking.
Sleep Inn & Suites

Sleep Inn & Suites

2.5 out of 5
105 Lakeside Dr, Hannibal, MO
Free Cancellation
Reserve now, pay when you stay
The price is $109 per night
This hotel features an indoor pool and a fitness center. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like full breakfast and free self parking.
Holiday Inn Express And Suites Hannibal - Medical Center, an IHG Hotel

Holiday Inn Express And Suites Hannibal - Medical Center, an IHG Hotel

2.5 out of 5
120 Shinn Lane, Hannibal, MO
Free Cancellation
The price is $123 per night
This hotel features an indoor pool and a fitness center. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal

2.5 out of 5
4000 Market St, Hannibal, MO
Free Cancellation
Reserve now, pay when you stay
The price is $99 per night
This hotel features an indoor pool and a 24-hour fitness center. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the spa tub and free perks like buffet breakfast and free self parking.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit in Louisiana

Image for Mark Twain Boyhood Home and Museum

Mark Twain Boyhood Home and Museum

Find out about the history of Hannibal when you take a trip to Mark Twain Boyhood Home and Museum. While in this walkable area, you can savor the top-notch restaurants.

Mark Twain Boyhood Home and Museum
Image for Mark Twain Memorial Lighthouse

Mark Twain Memorial Lighthouse

You can find out about the history of Hannibal with a stop at Mark Twain Memorial Lighthouse. While in this family-friendly area, you can savor the top-notch restaurants.

Mark Twain Memorial Lighthouse
Image for Bluff City Theater

Bluff City Theater

Enjoy a show at Bluff City Theater, a theater with a story to tell in Hannibal. While in this family-friendly area, you can savor the top-notch restaurants.

Bluff City Theater

Frequently asked questions

^Savings based on all package bookings with Flight + Hotel made on Travelocity.com from 2019-04-01 - 2020-03-31 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.