The St. Regis Cairo offers 362 accommodations, which are accessible via exterior corridors and feature iPod docking stations and MP3 docking stations. Pillowtop beds feature Egyptian cotton sheets and premium bedding. A pillow menu is available. Guests can make use of the in-room espresso makers and minibars. Bathrooms include separate bathtubs and showers, bathrobes, slippers, and bidets.
Guests can surf the web using the complimentary wireless Internet access. Business-friendly amenities include desks, safes, and phones. Additionally, rooms include complimentary bottled water and hair dryers. Hypo-allergenic bedding, change of towels, and change of bedsheets can be requested. A nightly turndown service is provided and housekeeping is offered daily.