
Cheap American Airlines flights from Louisville to La Crosse (SDF to LSE)
Find The Best Day To Fly from Louisville to La Crosse
Amazing American Airlines SDF to LSE Flight Deals
The cheapest flights to La Crosse Municipal found within the past 7 days were $498 round trip and one way. Prices and availability subject to change. Additional terms may apply.
Discover our best American Airlines flight from Louisville SDF to La Crosse LSE
To find the best deals on flights to Louisville from La Crosse with American Airlines, just enter your travel dates, filter by American Airlines, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.
Return flights from Louisville SDF to La Crosse LSE with American Airlines
If you’re planning a round trip, booking return flights with American Airlines is usually the most cost-effective option. With airfares ranging from $498 to $943, it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply.
Book one-way American Airlines flights from Louisville SDF to La Crosse LSE
A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way American Airlines flight from Louisville to La Crosse costs from . Prices and availability subject to change. Additional terms may apply.
The easy way to find cheap flights to La Crosse LSE from Louisville SDF with American Airlines
To find a cheap American Airlines flight from Louisville SDF to La Crosse LSE, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference.
How to find our best airfare deals on American Airlines flights from Louisville SDF to La Crosse LSE
If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as March, or if you book a flight with a stopover.
Find nonstop flights from Louisville SDF to La Crosse LSE with American Airlines
If you’re keen to be on La Crosse soil fast, don’t waste time with a stopover—filter your search results to show direct American Airlines flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it.
Flexible airline tickets for American Airlines flights from Louisville SDF to La Crosse LSE
Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.
There are a lot of reasons to book your flights to La Crosse LSE from Louisville SDF with American Airlines on Travelocity
At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.
Travelers ❤️ these 🏨 after their flight to La Crosse

Reviewed on May 5, 2025

Reviewed on Apr 25, 2025

Reviewed on May 5, 2025
More Ways To Wander
Popular American Airlines Flight Routes from SDF
Top American Airlines Flight Routes from LSE
Top Flights for American Airlines originating from SDF
Domestic
- Newark Liberty Intl. Airport to Miami (EWR - MIA)
- Chicago to San Salvador (ORD - SAL)
- New York to Las Vegas (JFK - LAS)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Philadelphia to Orlando (PHL - MCO)
- New York to Orlando (JFK - MCO)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- New York to Santo Domingo (JFK - SDQ)
- Philadelphia to San Juan (PHL - SJU)
- New York to Las Vegas (JFK - LAS)
International
- Lisbon to Toronto (LIS - YYZ)
- New York to San Juan (JFK - SJU)
- Newark Liberty Intl. Airport to Las Vegas (EWR - LAS)
- Philadelphia to San Juan (PHL - SJU)
- Atlanta to New York (ATL - LGA)
- San Juan to Orlando (SJU - MCO)
- New York to Orlando (JFK - MCO)
- Newark Liberty Intl. Airport to Santiago (EWR - STI)
- New York to San Juan (JFK - SJU)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)