Explore 16 Luxury Hotels in Winston-Salem

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Best Luxury Hotels in Winston-Salem

The Historic Brookstown Inn, Trademark Collection by Wyndham

The Historic Brookstown Inn, Trademark Collection by Wyndham

200 Brookstown Ave, Winston-Salem, NC
Fully refundableReserve now, pay when you stay
$121 nightly
The price is $136 total per night from Sep 28 to Sep 29
$136 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the express ...
9.4/10 Exceptional! (1,008 reviews)
"Always enjoy staying at the lovely Brookstown Inn!"

Reviewed on Sep 19, 2025

Opens in a new windowThe Historic Brookstown Inn, Trademark Collection by Wyndham
Kimpton Cardinal Hotel by IHG

Kimpton Cardinal Hotel by IHG

51 East 4th St, Winston-Salem, NC
Fully refundable
$172 nightly
The price is $194 total per night from Oct 5 to Oct 6
$194 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. There's fun for all ages with a bowling alley and a playground, and complimentary bicycles ...
9/10 Wonderful! (1,003 reviews)
"This place is awesome"

Reviewed on Sep 17, 2025

Opens in a new windowKimpton Cardinal Hotel by IHG
Courtyard by Marriott Winston-Salem University

Courtyard by Marriott Winston-Salem University

3111 University Pkwy, Winston-Salem, NC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $112 total per night from Oct 12 to Oct 13
$112 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
8.4/10 Very Good! (732 reviews)
Friendly, Clean, and Quiet
"We stayed for the night. Desk clerk was very nice. Hotel was very clean and quiet. Every person working in the hotel was nice. Breakfast was good at the Bistro and the ladies working there were excellent! So very glad we chose this hotel!"

Reviewed on Sep 17, 2025

Opens in a new windowCourtyard by Marriott Winston-Salem University
Hawthorne Inn and Conference Center

Hawthorne Inn and Conference Center

420 High St, Winston-Salem, NC
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $89 total per night from Sep 29 to Sep 30
$89 total
Sep 29 - Sep 30
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Guests will appreciate free perks like free self parking and WiFi in public areas. Express check-out, ...
8.2/10 Very Good! (1,023 reviews)
"This hotel is terrific! I am so glad I stayed there. People were great! Room was great! View of trees from my big glass windows was great! I will recommend Hawthorne Inn and Conference Center and stay there again myself."

Reviewed on Sep 21, 2025

Opens in a new windowHawthorne Inn and Conference Center
Sleep Inn Hanes Mall

Sleep Inn Hanes Mall

1985 Hampton Inn Ct, Winston-Salem, NC
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $78 total per night from Oct 5 to Oct 6
$78 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
7.8/10 Good! (1,004 reviews)
"The staff was so kind and accommodative to my request. Thank you."

Reviewed on Sep 13, 2025

Opens in a new windowSleep Inn Hanes Mall
Best Western Plus University Inn

Best Western Plus University Inn

3050 University Pkwy, Winston-Salem, NC
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $85 total per night from Sep 28 to Sep 29
$85 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
7.2/10 Good! (1,003 reviews)
"Great service"

Reviewed on Sep 18, 2025

Opens in a new windowBest Western Plus University Inn
Quality Inn & Suites Hanes Mall

Quality Inn & Suites Hanes Mall

2008 S Hawthorne Rd, Winston-Salem, NC
Fully refundableReserve now, pay when you stay
$54 nightly
The price is $61 total per night from Sep 28 to Sep 29
$61 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 3 conference ...
6.8/10 (1,005 reviews)
"No coffee after 9am"

Reviewed on Sep 17, 2025

Opens in a new windowQuality Inn & Suites Hanes Mall
HomeTowne Studios by Red Roof Winston-Salem - University Pkwy

HomeTowne Studios by Red Roof Winston-Salem - University Pkwy

7910 N Point Blvd, Winston-Salem, NC
$55 nightly
The price is $63 total per night from Sep 29 to Sep 30
$63 total
Sep 29 - Sep 30
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Laundry facilities are provided for your convenience.
5.4/10 (1,001 reviews)
"Checking lady was awesome and explained everuthing thoroughly."

Reviewed on Sep 16, 2025

Opens in a new windowHomeTowne Studios by Red Roof Winston-Salem - University Pkwy
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More 4 star hotels in Winston-Salem

Winston-Salem Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Winston-Salem luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Winston-Salem to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Winston-Salem will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Winston-Salem, and plan your next opulent escape.


Winston-Salem hotels essential information

Accommodation
1,351 hotels
Lowest Price
$61
Highest Price
$1,016
Popular hotels
Kimpton Cardinal Hotel by IHG, The Historic Brookstown Inn, Trademark Collection by Wyndham, Hawthorne Inn and Conference Center, Quality Inn & Suites Hanes Mall, Courtyard by Marriott Winston-Salem University, Sleep Inn Hanes Mall, Best Western Plus University Inn, HomeTowne Studios by Red Roof Winston-Salem - University Pkwy

Popular Luxury Stays in Winston-Salem

Recent Winston-Salem Hotel Reviews By Fellow Wanderers

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