Book Hotels in Southwest Illinois, IL
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Top Southwest Illinois hotels
Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive O'Fallon IL
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $118 total per night from Oct 12 to Oct 13
$118 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"Staff very professional and friendly. Food delicious."
Reviewed on Sep 25, 2026
Drury Inn & Suites St. Louis Collinsville
602 N Bluff Rd Collinsville IL
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $128 total per night from Oct 12 to Oct 13
$128 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"Best bacon .."
Reviewed on Sep 25, 2026
Comfort Inn Edwardsville - St. Louis
3080 S State Route 157 Edwardsville IL
Fully refundable
$95 nightly
The price is $109 total per night from Oct 18 to Oct 19
$109 total
Oct 18 - Oct 19
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...
"Staff eas great. Room very nice and clean Lovely breakfast"
Reviewed on Sep 25, 2026
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
Fully refundableReserve now, pay when you stay
$54 nightly
The price is $62 total per night from Oct 13 to Oct 14
$62 total
Oct 13 - Oct 14
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Clean"
Reviewed on Sep 24, 2026
Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $114 total per night from Sep 27 to Sep 28
$114 total
Sep 27 - Sep 28
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Drury Inn & Suites Marion
2706 W DeYoung St Marion IL
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $115 total per night from Oct 18 to Oct 19
$115 total
Oct 18 - Oct 19
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $125 total per night from Oct 4 to Oct 5
$125 total
Oct 4 - Oct 5
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Quality Inn O'Fallon - St. Louis - Shiloh
1409 W US 50 O'Fallon IL
Fully refundable
$61 nightly
The price is $70 total per night from Oct 20 to Oct 21
$70 total
Oct 20 - Oct 21
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Walker's Bluff Casino Resort
777 Walkers Bluff Way Carterville IL
Fully refundableReserve now, pay when you stay
$156 nightly
The price is $173 total per night from Sep 28 to Sep 29
$173 total
Sep 28 - Sep 29
Total with taxes and fees
This luxury resort features a casino, a full-service spa, and 3 restaurants. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
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See all available properties in Southwest Illinois
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southwest Illinois hotels
Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr Caseyville IL
$59 nightly
The price is $67 total per night from Oct 1 to Oct 2
$67 total
Oct 1 - Oct 2
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southwest Illinois with star-rating
Check Southwest Illinois Hotels by Star Rating
4 Star Hotels
3 properties
Recent Southwest Illinois hotel reviews by fellow wanderers
Comfort Inn Edwardsville - St. Louis
5 out of 5
Posted 7 hours ago
Travelocity Verified Review
"Staff eas great. Room very nice and clean Lovely breakfast"
A verified traveler stayed at Comfort Inn Edwardsville - St. Louis
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