Book Hotels in Southwest Illinois, IL
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Top Southwest Illinois hotels

Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive O'Fallon IL
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $123 total per night from Mar 15 to Mar 16
$123 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
The room was comfortable, and clean. The beds had plenty of pillows and a comfortable bed. The check in process was quick. The room had a clean bathroom and shower, with plenty of towels for us. The only issue I would bring up is that there was only 1 operational elevator which meant a delay in getting ...
Reviewed on Mar 9, 2026

Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $125 total per night from Apr 3 to Apr 4
$125 total
Apr 3 - Apr 4
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
I booked for 3/9-3/10/26. We arrived today and were told the reservation was for last night. I’m Very clear that I selected a stay fo tonight. I have no idea how it got changed to last night. Please refund me in full for the incorrect reservation last night.
Reviewed on Mar 9, 2026

Drury Inn & Suites Marion
2706 W DeYoung St Marion IL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $113 total per night from Apr 5 to Apr 6
$113 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Great!
Reviewed on Mar 10, 2026

Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
$94 nightly
The price is $106 total per night from Mar 15 to Mar 16
$106 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
We were very happy wirh the hotel and our room
Reviewed on Mar 10, 2026

Comfort Suites Mount Vernon
404 South 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $124 total per night from Apr 5 to Apr 6
$124 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
yes
Reviewed on Mar 10, 2026

Best Western Marion Hotel
400 Comfort Dr Marion IL
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $91 total per night from Mar 12 to Mar 13
$91 total
Mar 12 - Mar 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Felt safe and at home. Will use it again
Reviewed on Mar 10, 2026

Red Lion Inn & Suites Pontoon Beach
1240 E Chain Of Rocks Rd Granite City IL
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $85 total per night from Apr 5 to Apr 6
$85 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free continental breakfast each morning. Staff at the 24-hour ...
There was a weird smell in every hall room etc here. The room was not horrible, good enough for a one night stay. The bed was SUPER comfortable. Perfect drive to st. louis for a concert. I would stay here again for the price
Reviewed on Mar 8, 2026

Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
Fully refundableReserve now, pay when you stay
$51 nightly
The price is $59 total per night from Mar 12 to Mar 13
$59 total
Mar 12 - Mar 13
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
This was the worst hotel that I had ever stayed in and NEVER again. I stayed at this hotel location years ago and it has deteriorated to the point that there are no words. My husband and I contemplated leaving, but we stayed the 2 nights out of necessity. We were in town for a funeral and needed ...
Reviewed on Mar 9, 2026

Comfort Suites Fairview Heights - St. Louis
137 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $90 total per night from Apr 1 to Apr 2
$90 total
Apr 1 - Apr 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Room was so bad i did not complete my stay. Booked room to avoid having drive back home in a storm but ENDED UP DRIVING HOME IN THE STORM.. Tub was flithy splats of food or something was on the dresser. Got bitten by a bug sitting on the bed..went to either get a clean accommodating room waited several ...
Reviewed on Mar 10, 2026
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southwest Illinois hotels

Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr Caseyville IL
$63 nightly
The price is $71 total per night from Mar 12 to Mar 13
$71 total
Mar 12 - Mar 13
Total with taxes and fees
6.4/10 (1,002 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southwest Illinois with star-rating
Check Southwest Illinois Hotels by Star Rating

4 Star Hotels
4 properties
Recent Southwest Illinois hotel reviews by fellow wanderers

Quality Inn & Suites near St. Louis and I-255
1 out of 5
Posted 9 hours ago
Travelocity Verified Review
"Toilet didn’t work handle was broken "
A verified traveler stayed at Quality Inn & Suites near St. Louis and I-255
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