Book Hotels in Southwest Illinois, IL
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Top Southwest Illinois hotels

Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive O'Fallon IL
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $123 total per night from May 3 to May 4
$123 total
May 3 - May 4
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Everything was excellent! The staff was awesome! It was all and more that we needed.
Reviewed on Apr 28, 2026

Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $116 total per night from May 3 to May 4
$116 total
May 3 - May 4
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Nice meals
Reviewed on Apr 28, 2026

Walker's Bluff Casino Resort
777 Walkers Bluff Way Carterville IL
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $130 total per night from May 6 to May 7
$130 total
May 6 - May 7
Total with taxes and fees
This luxury resort features a casino, a full-service spa, and 3 restaurants. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
Hotel and casino were clean well run.
Reviewed on Apr 27, 2026

Drury Inn & Suites Marion
2706 W DeYoung St Marion IL
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $115 total per night from May 17 to May 18
$115 total
May 17 - May 18
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Everything was in good working order friendly staff great place
Reviewed on Apr 27, 2026

Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $110 total per night from May 3 to May 4
$110 total
May 3 - May 4
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Great hotel everything was perfect
Reviewed on Apr 25, 2026

Comfort Suites Mount Vernon
404 South 44th Street Mount Vernon IL
Fully refundable
$113 nightly
The price is $127 total per night from May 3 to May 4
$127 total
May 3 - May 4
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Excellent breakfast!
Reviewed on Apr 24, 2026

Super 8 by Wyndham Troy IL/St. Louis Area
910 Edwardsville Rd Troy IL
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $80 total per night from May 5 to May 6
$80 total
May 5 - May 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Other than the storm knockingnout the power in the area off an on. Great stay extremely friendly staff
Reviewed on Apr 29, 2026

Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Dr East St. Louis IL
Fully refundable
$72 nightly
The price is $82 total per night from May 5 to May 6
$82 total
May 5 - May 6
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Ac didnt work.. roaches
Reviewed on Apr 26, 2026

Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $68 total per night from May 5 to May 6
$68 total
May 5 - May 6
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Dirty, roaches, no elevator, bad smell
Reviewed on Apr 27, 2026
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See all available properties in Southwest Illinois
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southwest Illinois hotels

Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr Caseyville IL
$60 nightly
The price is $68 total per night from Apr 30 to May 1
$68 total
Apr 30 - May 1
Total with taxes and fees
6.4/10 (1,000 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southwest Illinois with star-rating
Check Southwest Illinois Hotels by Star Rating

4 Star Hotels
3 properties
Recent Southwest Illinois hotel reviews by fellow wanderers

Super 8 by Wyndham Troy IL/St. Louis Area
5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Other than the storm knockingnout the power in the area off an on. Great stay extremely friendly staff "
A verified traveler stayed at Super 8 by Wyndham Troy IL/St. Louis Area
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