Book Hotels in Southwest Illinois, IL
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Top Southwest Illinois hotels
Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $125 total per night from Aug 16 to Aug 17
$125 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"Great & unique indoor/outdoor pool. Free dinner & drinks along with breakfast, what more could want!"
Reviewed on Aug 10, 2026
Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive O'Fallon IL
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $123 total per night from Aug 16 to Aug 17
$123 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"Clean and staff was helpful didn’t stay for breakfast unfortunately or use the pool but they did look nice"
Reviewed on Aug 9, 2026
Comfort Suites Fairview Heights - St. Louis
137 Ludwig Dr Fairview Heights IL
$76 nightly
The price is $85 total per night from Aug 31 to Sep 1
$85 total
Aug 31 - Sep 1
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Service was good. Rooms were as expected for the price. However, one room had a bad smell that I think was coming from the tub. Swimming pool was not good. Very cloudy water and smelled of algae. Overall not bad for the price."
Reviewed on Aug 9, 2026
Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Aug 16 to Aug 17
$102 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Best Western St. Louis Fairview Heights
150 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $90 total per night from Aug 16 to Aug 17
$90 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Country Inn & Suites by Radisson, Fairview Heights, IL
140 Ludwig Drive Fairview Heights IL
Fully refundable
$81 nightly
The price is $91 total per night from Sep 6 to Sep 7
$91 total
Sep 6 - Sep 7
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
Fully refundableReserve now, pay when you stay
$54 nightly
The price is $62 total per night from Aug 17 to Aug 18
$62 total
Aug 17 - Aug 18
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
The Principal Hotel
310 S Main St Columbia IL
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $109 total per night from Aug 13 to Aug 14
$109 total
Aug 13 - Aug 14
Total with taxes and fees
A restaurant and a gym are featured at this hotel. Free self parking, a coffee shop, and dry cleaning are also offered.
Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Dr East St. Louis IL
Fully refundable
$73 nightly
The price is $83 total per night from Sep 1 to Sep 2
$83 total
Sep 1 - Sep 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Don't see what you're looking for?
See all available properties in Southwest Illinois
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southwest Illinois hotels
Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr Caseyville IL
$61 nightly
The price is $69 total per night from Aug 16 to Aug 17
$69 total
Aug 16 - Aug 17
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southwest Illinois with star-rating
Check Southwest Illinois Hotels by Star Rating
4 Star Hotels
3 properties
Recent Southwest Illinois hotel reviews by fellow wanderers
Drury Plaza Hotel Mt. Vernon
5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Great & unique indoor/outdoor pool. Free dinner & drinks along with breakfast, what more could want!"
A verified traveler stayed at Drury Plaza Hotel Mt. Vernon
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