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Top hotels in Santa Ana
The Executive Hotel
Calle 52 Panama City Panama
$88 nightly
The price is $97 total per night from Mar 22 to Mar 23
$97 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Enjoyed my stay it was perfect for my solo trip! Room was fine bu wish there was a chair and table to enjoy on the balcony. Downside was not having any usb ports by the bed or at the desk. It’s 2026 please upgrade the bedside lamps with USB’s. Also elevators are the smallest I’ve ever been in so ...
Reviewed on Mar 17, 2026
Casco View Apartments
C. 16 Oeste Panama City Provincia de Panamá
$119 nightly
The price is $131 total per night from Apr 17 to Apr 18
$131 total
Apr 17 - Apr 18
Total with taxes and fees
An outdoor pool is featured at this condo, along with a terrace and a garden. Staff at the 24-hour front desk can provide around-the-clock assistance.
Honest review of apartments clean well organized minimalist, but with ok essentials in the kitchens, paper towels., few cleaning supplies look under sink., everything neat in and order. Large sliding glass window, but the view is of interesting neighborhood) ocean (window in bedroom is to hallway) ...
Reviewed on Mar 6, 2026
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
$157 nightly
The price is $172 total per night from Mar 30 to Mar 31
$172 total
Mar 30 - Mar 31
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Clean and comfortable room. Staff were very nice and breakfast was delicious.
Reviewed on Mar 17, 2026
W Panama
Calle Aquilino de la Guardia & Calle 50 Panama City
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $219 total per night from Mar 31 to Apr 1
$219 total
Mar 31 - Apr 1
Total with taxes and fees
This luxury hotel features 2 restaurants, 3 hot tubs, and an outdoor pool. Make the most of the gym and a rooftop terrace, and relax with drinks at one of the ...
The spa was amazing, I never went to a spa that washes your feet before a massage. What an amazing experience. Job well done. The hotel was so nice and our room omg just beautiful, we stayed in the supreme corner room and enjoyed every moment. Next time we have to stay a longer time because our 5 ...
Reviewed on Mar 16, 2026
Principe Hotel and Suites
Via Argentina Panama City Panama
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $62 total per night from Mar 18 to Mar 19
$62 total
Mar 18 - Mar 19
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
No kitchen
Reviewed on Mar 16, 2026
Waymore Hotel Spa & Casino
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $104 total per night from Mar 25 to Mar 26
$104 total
Mar 25 - Mar 26
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free bed & breakfast. Traveling on business? Take advantage of the free ...
The room and the breakfast are excelent, the staff is also really great.
Reviewed on Mar 16, 2026
Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
Fully refundable
$134 nightly
The price is $147 total per night from Mar 23 to Mar 24
$147 total
Mar 23 - Mar 24
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate the children's pool, onsite laundry facilities, and babysitting. ...
I stay only for one night , from 11:00 PM to 6:30 am so I really can’t said much about it.
Reviewed on Mar 17, 2026
Sheraton Grand Panama
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $139 total per night from Apr 3 to Apr 4
$139 total
Apr 3 - Apr 4
Total with taxes and fees
A full-service spa, 3 restaurants, and 3 outdoor tennis courts are all featured at this smoke-free resort. Families will appreciate the playground, kid-friendly ...
El personal de servicio excelente muy amables y te ayudaban a encontrar lugares para visitar
Reviewed on Mar 16, 2026
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Via Espana 111 Panama City Panama
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $119 total per night from Mar 23 to Mar 24
$119 total
Mar 23 - Mar 24
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 3 restaurants. Families will appreciate the children's pool, onsite laundry facilities, and ...
My stay here was really great. Close to everything, a safe area, wonderful happy friendly staff, awesome breakfast & the premises clean. I'll stay here again certainly.
Reviewed on Mar 15, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Santa Ana Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Santa Ana area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Santa Ana to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Santa Ana are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Santa Ana hotel reviews by fellow wanderers
Hotel Riu Plaza Panama
5 out of 5
Posted 8 hours ago
Travelocity Verified Review
"Clean and comfortable room. Staff were very nice and breakfast was delicious. "
A verified traveler stayed at Hotel Riu Plaza Panama
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