South Carolina Midlands , SC Pet Friendly Hotels

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Top South Carolina Midlands Pet Friendly Hotels

Hampton Inn Columbia I-26/Harbison Blvd.

Hampton Inn Columbia I-26/Harbison Blvd.

101 Woodcross Dr Columbia SC
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $107 total per night from Nov 30 to Dec 1
$107 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
9/10 Wonderful! (1,002 reviews)
clean room, convenient location, affordable price

Reviewed on Nov 13, 2025

Opens in a new windowHampton Inn Columbia I-26/Harbison Blvd.
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

139 Bradford Blvd Santee SC
Fully refundable
$111 nightly
The price is $123 total per night from Nov 23 to Nov 24
$123 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
8/10 Very Good! (965 reviews)
Was very nice except we could hear the elevator every time it went up and down. Staff were great. Place was clean even though it was under remodeling. Liked having a bar and restaurant to eat at inside.

Reviewed on Nov 13, 2025

Opens in a new windowHoliday Inn Santee by IHG
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

2123 W Lucas St Florence SC
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $99 total per night from Dec 12 to Dec 13
$99 total
Dec 12 - Dec 13
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
7.8/10 Good! (1,675 reviews)
motel very clean. Staffs very professional. Breakfast very nice with hot food and coffee. Fresh water. Juice available with breakfasts. LOBBY and dining have inviting atmosphere

Reviewed on Nov 10, 2025

Opens in a new windowLa Quinta Inn & Suites by Wyndham Florence
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

7333 Garners Ferry Rd Columbia SC
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $89 total per night from Dec 14 to Dec 15
$89 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 24-hour ...
7.6/10 Good! (1,004 reviews)
This was the best experience I’ve had in a while, staying in a hotel.

Reviewed on Nov 20, 2025

Opens in a new windowLa Quinta Inn by Wyndham Columbia SE / Fort Jackson
Spark by Hilton Orangeburg

Spark by Hilton Orangeburg

731 Citadel Road Orangeburg SC
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $97 total per night from Nov 30 to Dec 1
$97 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
7.6/10 Good! (1,001 reviews)
Yes mais nous navons pas coucher la car javais reserve et je me suis trompe de date ils nont pas voulus nous accepter et collecter latgent plus tard par Hotel Com. Cest regrettanle jai perdu mon argent je ne pensre plus utileser Hotel.com, Verbo et autres

Reviewed on Nov 12, 2025

Opens in a new windowSpark by Hilton Orangeburg
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

150 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $95 total per night from Dec 21 to Dec 22
$95 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
7.6/10 Good! (1,245 reviews)
Older but clean hotel. Very convenient. Would stay again.

Reviewed on Nov 13, 2025

Opens in a new windowQuality Inn & Suites Florence Civic Center
Best Western Inn

Best Western Inn

1808 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $88 total per night from Dec 14 to Dec 15
$88 total
Dec 14 - Dec 15
Total with taxes and fees
A seasonal outdoor pool is featured at this hotel, along with free self parking. Guests will appreciate free perks like continental breakfast and WiFi in public ...
7.6/10 Good! (1,003 reviews)
Courteous and polite Staff

Reviewed on Nov 14, 2025

Opens in a new windowBest Western Inn
Red Roof Inn Florence - Civic Center

Red Roof Inn Florence - Civic Center

2690 David H McLeod Boulevard Florence SC
Fully refundableReserve now, pay when you stay
$56 nightly
The price is $63 total per night from Nov 24 to Nov 25
$63 total
Nov 24 - Nov 25
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...
6.6/10 (1,003 reviews)
Clean and comfy

Reviewed on Nov 9, 2025

Opens in a new windowRed Roof Inn Florence - Civic Center
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

It’s hard to leave for a trip when the last image you have is of your four-legged best friend staring out the living-room window with those sad eyes as you drive away. You don’t have to leave Spot behind any longer, he can finally join you on your adventures.

Turn your trip into a family getaway by booking a stay at one of the pet-friendly hotels in South Carolina Midlands for you and your furry kids. No more sending them to pet hotels or leaving them home alone to run amok in the house. South Carolina Midlands pet-friendly hotels are perfect for weekend escapes with your pooch, kitty, bird, or fish. These accommodations not only welcome your pets, but they offer many services to help make your stay more relaxing. Things like on-site grooming and complimentary dog walking are some of the amenities provided. In most cases, you’ll also be near outdoor spaces like dog parks if you both need some exercise, as well as pet-friendly restaurants.

Don’t ever feel guilty about leaving your beloved Maximus behind on a trip again. Travelocity wants to help the both of you enjoy a wonderful vacation together. Search our extensive inventory of the best pet-friendly hotels in South Carolina Midlands and book your stay now.

South Carolina Midlands hotels essential information

Accommodation
3,012 hotels
Lowest Price
$63
Highest Price
$123
Popular hotels
La Quinta Inn & Suites by Wyndham Florence, La Quinta Inn by Wyndham Columbia SE / Fort Jackson, Hampton Inn Columbia I-26/Harbison Blvd., Spark by Hilton Orangeburg, Quality Inn & Suites Florence Civic Center, Holiday Inn Santee by IHG, Red Roof Inn Florence - Civic Center, Best Western Inn

Recent South Carolina Midlands hotel reviews by fellow wanderers

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