South Carolina Midlands , SC Pet Friendly Hotels

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Top South Carolina Midlands Pet Friendly Hotels

Hampton Inn Columbia I-26/Harbison Blvd.

Hampton Inn Columbia I-26/Harbison Blvd.

101 Woodcross Dr, Columbia, SC
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $113 total per night from Aug 31 to Sep 1
$113 total
Aug 31 - Sep 1
Total includes taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
9/10 Wonderful! (1,001 reviews)
"Great stalk, clean rooms , nice breakfast"

Reviewed on Aug 14, 2025

Hampton Inn Columbia I-26/Harbison Blvd.
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

139 Bradford Blvd, Santee, SC
$118 nightly
The price is $131 total per night from Sep 18 to Sep 19
$131 total
Sep 18 - Sep 19
Total includes taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
8/10 Very Good! (931 reviews)
"The staff were great from checking in to checking out. The room was very clean and well kept. Would highly recommend."

Reviewed on Aug 6, 2025

Holiday Inn Santee by IHG
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

2123 W Lucas St, Florence, SC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $111 total per night from Aug 28 to Aug 29
$111 total
Aug 28 - Aug 29
Total includes taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
7.8/10 Good! (1,683 reviews)
"this property was nice and clean. they did cme around but once to see if we needed towles or room cleaned we told them at desk and they were suppose to come to service but never did but other than that no other issues"

Reviewed on Aug 20, 2025

La Quinta Inn & Suites by Wyndham Florence
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

150 Dunbarton Dr, Florence, SC
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $101 total per night from Aug 26 to Aug 27
$101 total
Aug 26 - Aug 27
Total includes taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
7.8/10 Good! (1,236 reviews)
Excellent stay
"Excellent, friendly staff. Nice outdoor pool. Clean."

Reviewed on Aug 18, 2025

Quality Inn & Suites Florence Civic Center
Spark by Hilton Orangeburg

Spark by Hilton Orangeburg

731 Citadel Road, Orangeburg, SC
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $97 total per night from Aug 28 to Aug 29
$97 total
Aug 28 - Aug 29
Total includes taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
7.6/10 Good! (1,008 reviews)
"Good customer service and rooms were clean."

Reviewed on Aug 18, 2025

Spark by Hilton Orangeburg
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

7333 Garners Ferry Rd, Columbia, SC
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $85 total per night from Sep 7 to Sep 8
$85 total
Sep 7 - Sep 8
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 24-hour ...
7.4/10 Good! (1,002 reviews)
"My rooms was very clean and the staff was very friendly they had some maintenance going on which caused some delay but the staff was very understandable and didn’t charge extra, i can definitely see the vision for when the maintenance and upgrades are finished. only thing I didn’t like was the area ..."

Reviewed on Aug 13, 2025

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Red Roof Inn Florence - Civic Center

Red Roof Inn Florence - Civic Center

2690 David H McLeod Boulevard, Florence, SC
Fully refundableReserve now, pay when you stay
$56 nightly
The price is $63 total per night from Aug 24 to Aug 25
$63 total
Aug 24 - Aug 25
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...
6.6/10 (1,000 reviews)
"Wonderfully comfy bed"

Reviewed on Aug 10, 2025

Red Roof Inn Florence - Civic Center
Baymont Inn & Suites Florence by Wyndham

Baymont Inn & Suites Florence by Wyndham

1826 W Lucas Street, Florence, SC
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self ...
"Still in Renovation mode"

Reviewed on Sep 3, 2024

Baymont Inn & Suites Florence by Wyndham
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

It’s hard to leave for a trip when the last image you have is of your four-legged best friend staring out the living-room window with those sad eyes as you drive away. You don’t have to leave Spot behind any longer, he can finally join you on your adventures.

Turn your trip into a family getaway by booking a stay at one of the pet-friendly hotels in South Carolina Midlands for you and your furry kids. No more sending them to pet hotels or leaving them home alone to run amok in the house. South Carolina Midlands pet-friendly hotels are perfect for weekend escapes with your pooch, kitty, bird, or fish. These accommodations not only welcome your pets, but they offer many services to help make your stay more relaxing. Things like on-site grooming and complimentary dog walking are some of the amenities provided. In most cases, you’ll also be near outdoor spaces like dog parks if you both need some exercise, as well as pet-friendly restaurants.

Don’t ever feel guilty about leaving your beloved Maximus behind on a trip again. Travelocity wants to help the both of you enjoy a wonderful vacation together. Search our extensive inventory of the best pet-friendly hotels in South Carolina Midlands and book your stay now.

South Carolina Midlands hotels essential information

Accommodation
2,922 hotels
Lowest Price
$63
Highest Price
$131
Popular hotels
La Quinta Inn & Suites by Wyndham Florence, La Quinta Inn by Wyndham Columbia SE / Fort Jackson, Hampton Inn Columbia I-26/Harbison Blvd., Spark by Hilton Orangeburg, Quality Inn & Suites Florence Civic Center, Holiday Inn Santee by IHG, Red Roof Inn Florence - Civic Center, Baymont Inn & Suites Florence by Wyndham

Recent South Carolina Midlands hotel reviews by fellow wanderers

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