Book Hotels in Upstate South Carolina, SC
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Top Upstate South Carolina hotels
Hotel Hartness
120 Halston Avenue Greenville SC
Fully refundableReserve now, pay when you stay
$219 nightly
The price is $240 total per night from Aug 9 to Aug 10
$240 total
Aug 9 - Aug 10
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and perks like free self parking. ...
"Very nice community if you’re wanting a very quiet and relaxing stay."
Reviewed on Aug 5, 2026
Grand Bohemian Lodge Greenville, Autograph Collection
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
$361 nightly
The price is $396 total per night from Aug 27 to Aug 28
$396 total
Aug 27 - Aug 28
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
"Room with a beautiful view!"
Reviewed on Aug 4, 2026
Best Western Plus Greenville I-385 Inn & Suites
831 Congaree Rd Greenville SC
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $104 total per night from Aug 9 to Aug 10
$104 total
Aug 9 - Aug 10
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Breakfast and parking"
Reviewed on Aug 4, 2026
Hyatt Regency Greenville
220 N Main St Greenville SC
Fully refundableReserve now, pay when you stay
$157 nightly
The price is $172 total per night from Aug 16 to Aug 17
$172 total
Aug 16 - Aug 17
Total with taxes and fees
This smoke-free hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"They were very helpful with taking initiative. No complaints."
Reviewed on Aug 3, 2026
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd Greenville SC
Fully refundable
$99 nightly
The price is $110 total per night from Aug 16 to Aug 17
$110 total
Aug 16 - Aug 17
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Very clean and quiet."
Reviewed on Aug 5, 2026
Hyatt Place Greenville/Haywood
40 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $91 total per night from Aug 24 to Aug 25
$91 total
Aug 24 - Aug 25
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Hyatt Place Greenville Downtown
128 East Broad Street Greenville SC
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $153 total per night from Aug 16 to Aug 17
$153 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $111 total per night from Aug 16 to Aug 17
$111 total
Aug 16 - Aug 17
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $117 total per night from Aug 16 to Aug 17
$117 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
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See all available properties in Upstate South Carolina
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Upstate South Carolina hotels
Baymont by Wyndham Anderson Clemson
128 Interstate Blvd Anderson SC
$72 nightly
The price is $80 total per night from Aug 11 to Aug 12
$80 total
Aug 11 - Aug 12
Total with taxes and fees
7/10 Good! (913 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Upstate South Carolina with star-rating
Check Upstate South Carolina Hotels by Star Rating
4 Star Hotels
32 properties
Recent Upstate South Carolina hotel reviews by fellow wanderers
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
5 out of 5
Posted 8 hours ago
Travelocity Verified Review
"Very clean and quiet. "
A verified traveler stayed at Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
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