Book Hotels in Upstate South Carolina, SC
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Top Upstate South Carolina hotels
Grand Bohemian Lodge Greenville, Autograph Collection
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
$218 nightly
The price is $240 total per night from Feb 15 to Feb 16
$240 total
Feb 15 - Feb 16
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Relax with a drink at the bar/lounge and enjoy perks like free ...
Awesome place and service
Reviewed on Jan 23, 2026
Hampton Inn & Suites Greenville-Downtown-RiverPlace
171 Riverplace Greenville SC
Fully refundableReserve now, pay when you stay
$150 nightly
The price is $165 total per night from Feb 8 to Feb 9
$165 total
Feb 8 - Feb 9
Total with taxes and fees
This hotel features a 24-hour gym and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet ...
Breakfast fare needs improvement for a higher end Hampton Inn
Reviewed on Jan 25, 2026
Hyatt Place Greenville Downtown
128 East Broad Street Greenville SC
$122 nightly
The price is $134 total per night from Feb 1 to Feb 2
$134 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Great room - nicely designed shower - best shower experience ever! Very spacious room
Reviewed on Jan 24, 2026
Embassy Suites by Hilton Greenville Downtown Riverplace
250 Riverplace Greenville SC
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $170 total per night from Feb 8 to Feb 9
$170 total
Feb 8 - Feb 9
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public ...
Everything easy to get to and the room is very clean
Reviewed on Jan 22, 2026
Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $116 total per night from Feb 1 to Feb 2
$116 total
Feb 1 - Feb 2
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Great little breakfast!
Reviewed on Jan 23, 2026
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd Greenville SC
Fully refundable
$101 nightly
The price is $111 total per night from Feb 1 to Feb 2
$111 total
Feb 1 - Feb 2
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
room spotless. staff great.
Reviewed on Jan 2, 2026
Hilton Greenville
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $116 total per night from Feb 8 to Feb 9
$116 total
Feb 8 - Feb 9
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, ...
Place is very
Reviewed on Jan 21, 2026
Hyatt Place Greenville/Haywood
40 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $92 total per night from Feb 16 to Feb 17
$92 total
Feb 16 - Feb 17
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Friendly staff and comfortable room
Reviewed on Jan 21, 2026
Sleep Inn Spartanburg Southwest
501 South Blackstock Rd Spartanburg SC
Fully refundable
$66 nightly
The price is $73 total per night from Feb 1 to Feb 2
$73 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Girl at check-in was more focused on a personal phone call than checking us in. Was rude when informed that light switch did not turn on any lights in the room. Yelled up from lobby that you have to walk into the DARK room and turn light on next to the bed. Light by TV did not work, did not offer ...
Reviewed on Jan 6, 2026
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See all available properties in Upstate South Carolina
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Upstate South Carolina hotels
Baymont by Wyndham Anderson Clemson
128 Interstate Blvd Anderson SC
$60 nightly
The price is $66 total per night from Feb 2 to Feb 3
$66 total
Feb 2 - Feb 3
Total with taxes and fees
7/10 Good! (851 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Upstate South Carolina with star-rating
Check Upstate South Carolina Hotels by Star Rating
4 Star Hotels
11 properties
Recent Upstate South Carolina hotel reviews by fellow wanderers
Hampton Inn & Suites Greenville-Downtown-RiverPlace
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Wonderful staff and perfect location "
A verified traveler stayed at Hampton Inn & Suites Greenville-Downtown-RiverPlace
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