Find and compare 2 Star hotels in Upstate South Carolina

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Top Upstate South Carolina 2 Star hotels

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd Anderson SC
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Jan 18 to Jan 19
$70 total
Jan 18 - Jan 19
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
7.6/10 Good! (1,003 reviews)
Love it

Reviewed on Dec 26, 2025

Opens in a new windowDays Inn by Wyndham Anderson
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.5 out of 5
831 Congaree Rd Greenville SC
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $85 total per night from Jan 25 to Jan 26
$85 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
9/10 Wonderful! (1,432 reviews)
Everything was really great from start to finish. Check in was smooth because I did the preregistration on line.

Reviewed on Jan 4, 2026

Opens in a new windowBest Western Plus Greenville I-385 Inn & Suites
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $103 total per night from Jan 12 to Jan 13
$103 total
Jan 12 - Jan 13
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
8.2/10 Very Good! (1,000 reviews)
The staff especially stood out. The online check in and the front desk was an absolute breeze! I am pleased as all heck. The room was clean and is well laid out for me to work. I greatly appreciate it.

Reviewed on Jan 5, 2026

Opens in a new windowBest Western Plus Clemson Hotel & Conference Center
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $89 total per night from Jan 25 to Jan 26
$89 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
7.8/10 Good! (667 reviews)
Hotel was clean, inside and out. Front desk staff was very kind and helpful.

Reviewed on Jan 4, 2026

Opens in a new windowQuality Inn Seneca Clemson Area US-123
ECHO Suites Extended Stay by Wyndham Spartanburg

ECHO Suites Extended Stay by Wyndham Spartanburg

2 out of 5
490 W Blackstock Road Spartanburg SC
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $84 total per night from Jan 11 to Jan 12
$84 total
Jan 11 - Jan 12
Total with taxes and fees
A 24-hour gym, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Staff at the 24-hour front desk can provide ...
8/10 Very Good! (317 reviews)
Everything was great juts no service . Also my room had the loudest refrigerator on earth and was really hard to fall a sleep.

Reviewed on Jan 2, 2026

Opens in a new windowECHO Suites Extended Stay by Wyndham Spartanburg
Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

2 out of 5
1024 Woodruff Rd Greenville SC
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $76 total per night from Jan 25 to Jan 26
$76 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
8.2/10 Very Good! (1,003 reviews)
While some may want room service everyday, I'm glad they didn't seem to enter my room. They respected my privacy, and to me, that's more important than my room being clean everyday. This was my first time staying at a hotel and it was a simple yet successful experience.

Reviewed on Jan 3, 2026

Opens in a new windowMicrotel Inn & Suites by Wyndham Greenville / Woodruff Rd
Comfort Suites Greenville Airport

Comfort Suites Greenville Airport

2.5 out of 5
1371 Garlington Road Greenville SC
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $106 total per night from Jan 23 to Jan 24
$106 total
Jan 23 - Jan 24
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
9.2/10 Wonderful! (1,011 reviews)
Our stay at Comfort Suites Greenville Airport was excellent. Although we don’t often stay at Choice brand hotels, this property made us fans. The staff was consistently friendly and welcoming. Marie at the front desk especially stood out for her genuine kindness and helpfulness, and both management ...

Reviewed on Jan 6, 2026

Opens in a new windowComfort Suites Greenville Airport
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
1305 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $114 total per night from Jan 16 to Jan 17
$114 total
Jan 16 - Jan 17
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
8.2/10 Very Good! (1,001 reviews)
The room was immaculate and very comfortable.

Reviewed on Dec 27, 2025

Opens in a new windowComfort Inn & Suites Clemson - University Area
Motel 6 Greenville, SC

Motel 6 Greenville, SC

2 out of 5
2015 Wade Hampton Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$50 nightly
The price is $55 total per night from Jan 11 to Jan 12
$55 total
Jan 11 - Jan 12
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. The front desk is staffed around-the-clock and laundry facilities are ...
5.2/10 (729 reviews)
Room was not great but staff was excellent and very helpful.

Reviewed on Jan 4, 2026

Opens in a new windowMotel 6 Greenville, SC
Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall

2.5 out of 5
246 Congaree Road Greenville SC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $92 total per night from Jan 11 to Jan 12
$92 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
8/10 Very Good! (1,011 reviews)
The hotel is clean. Upon arrival I was a bit skeptical but house keeping came by the room everyday.

Reviewed on Jan 2, 2026

Opens in a new windowComfort Inn Greenville - Haywood Mall
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2 Star Hotels Upstate South Carolina

Looking to break out of your routine for some much needed rest and relaxation? Or maybe you’ve already decided it’s time for a trip and are trying to find affordable hotels in Upstate South Carolina that won’t bust your travel budget?

Upstate South Carolina 2 star hotels will give you everything you need to enjoy the city like a local, saving a ton of money so you can hit all the hot spots in town.

Have a delicious breakfast at your hotel to fuel up for your day of sightseeing, then enjoy amenities like fresh towels and linens, as well as a nice hot shower to unwind after a busy day of experiencing everything the city has to offer.

As you explore a new locale, or one you love to visit over and over, you can rest easy knowing you’re staying in a great hotel that lets you discover Upstate South Carolina and welcomes you back to a clean, comfortable room at night.

Browse Travelocity’s wide selection of 2 star hotels in Upstate South Carolina and find one that’s perfectly priced and places you next to all the best activities and sights. The town is your oyster, and we can help you seek out its secrets while sticking to your budget.

Recent Upstate South Carolina hotel reviews by fellow wanderers

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