Find and compare 2 Star hotels in Upstate South Carolina

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Top Upstate South Carolina 2 Star hotels

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $101 total per night from Mar 8 to Mar 9
$101 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
8.2/10 Very Good! (1,009 reviews)
The room was very clean, it was a room with a king bed and a sofa bed plus a microwave, mini fridge, coffee machine. The reception desk was very helpful when I had to do a late check in.

Reviewed on Mar 1, 2026

Opens in a new windowBest Western Plus Clemson Hotel & Conference Center
Sleep Inn Spartanburg Southwest

Sleep Inn Spartanburg Southwest

2.5 out of 5
501 South Blackstock Rd Spartanburg SC
Fully refundable
$62 nightly
The price is $69 total per night from Apr 1 to Apr 2
$69 total
Apr 1 - Apr 2
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
6/10 (559 reviews)
Carpet was sticky and disgusting. Bed sheets and pillow cases dirty. Shower was outdated and disgusting. Water was terrible. Door was uneven so there was huge gaps. We only stayed for a few hours and just left.

Reviewed on Mar 2, 2026

Opens in a new windowSleep Inn Spartanburg Southwest
Best Western Greenville Airport Inn

Best Western Greenville Airport Inn

2.5 out of 5
5009 Pelham Road Greenville SC
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $79 total per night from Mar 8 to Mar 9
$79 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Free perks include full breakfast, free self parking, and a roundtrip airport shuttle. A 24-hour business ...
7.8/10 Good! (1,002 reviews)
The pillows were horrid!!! There were 4 pillows on the bed and they were all 12 x 12 inches and extremely hard. I am not sure why you would expect people use these for sleep?!?! The room was clean but the door opened to an open porch that lead down the stairs and to the back of the parking lot. It ...

Reviewed on Feb 24, 2026

Opens in a new windowBest Western Greenville Airport Inn
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.5 out of 5
831 Congaree Rd Greenville SC
Fully refundableReserve now, pay when you stay
$83 nightly
The price is $92 total per night from Mar 15 to Mar 16
$92 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
9.2/10 Wonderful! (1,448 reviews)
Our bathroom was exceptionally clean …thank you housekeeping! The bed was comfortable as well as Pillows/sheets/blankets… there are plenty of lights and outlets. Our first room, the tv didn’t work properly & the staff immediately moved us down the hall. Love the coffee machine & the husband enjoyed ...

Reviewed on Mar 4, 2026

Opens in a new windowBest Western Plus Greenville I-385 Inn & Suites
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
1305 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $112 total per night from Mar 10 to Mar 11
$112 total
Mar 10 - Mar 11
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
8.2/10 Very Good! (1,001 reviews)
Nice

Reviewed on Feb 26, 2026

Opens in a new windowComfort Inn & Suites Clemson - University Area
Comfort Suites Greenville Airport

Comfort Suites Greenville Airport

2.5 out of 5
1371 Garlington Road Greenville SC
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $111 total per night from Mar 22 to Mar 23
$111 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
9.2/10 Wonderful! (1,004 reviews)
The staff was amazing. Clean place to stay.

Reviewed on Mar 2, 2026

Opens in a new windowComfort Suites Greenville Airport
Urban Boutique Hotel, BW Signature Collection

Urban Boutique Hotel, BW Signature Collection

2.5 out of 5
536 Wade Hampton Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $71 total per night from Mar 22 to Mar 23
$71 total
Mar 22 - Mar 23
Total with taxes and fees
A bar/lounge and a 24-hour front desk are featured at this motel, along with free self parking. Guests will appreciate free perks like on-the-go breakfast and ...
8/10 Very Good! (962 reviews)
Over all great stay for the price

Reviewed on Feb 27, 2026

Opens in a new windowUrban Boutique Hotel, BW Signature Collection
Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall

2.5 out of 5
246 Congaree Road Greenville SC
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $97 total per night from Mar 22 to Mar 23
$97 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
8/10 Very Good! (1,002 reviews)
I didn't like the hotel at all. The breakfast was awful; there was no milk, no cream cheese, no variety whatsoever. The rooms had half-painted walls with patches of other colors. It's in a very good location, but the hotel is horrible and the service is just as bad.

Reviewed on Mar 3, 2026

Opens in a new windowComfort Inn Greenville - Haywood Mall
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Mar 5 to Mar 6
$135 total
Mar 5 - Mar 6
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and perks like free self parking and free WiFi. You'll appreciate ...
9/10 Wonderful! (1,002 reviews)
spacious "lake view" room. good value

Reviewed on Mar 2, 2026

Opens in a new windowLakeside Lodge Clemson
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd Anderson SC
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Mar 8 to Mar 9
$70 total
Mar 8 - Mar 9
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
7.8/10 Good! (1,006 reviews)
Front desk worker are always awesome. Hotel is always being renovated. Always clean. No complaints!

Reviewed on Mar 1, 2026

Opens in a new windowDays Inn by Wyndham Anderson
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2 Star Hotels Upstate South Carolina

Looking to break out of your routine for some much needed rest and relaxation? Or maybe you’ve already decided it’s time for a trip and are trying to find affordable hotels in Upstate South Carolina that won’t bust your travel budget?

Upstate South Carolina 2 star hotels will give you everything you need to enjoy the city like a local, saving a ton of money so you can hit all the hot spots in town.

Have a delicious breakfast at your hotel to fuel up for your day of sightseeing, then enjoy amenities like fresh towels and linens, as well as a nice hot shower to unwind after a busy day of experiencing everything the city has to offer.

As you explore a new locale, or one you love to visit over and over, you can rest easy knowing you’re staying in a great hotel that lets you discover Upstate South Carolina and welcomes you back to a clean, comfortable room at night.

Browse Travelocity’s wide selection of 2 star hotels in Upstate South Carolina and find one that’s perfectly priced and places you next to all the best activities and sights. The town is your oyster, and we can help you seek out its secrets while sticking to your budget.

Recent Upstate South Carolina hotel reviews by fellow wanderers

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