Book a hotel near Lignumvitae Key Botanical State Park, Islamorada

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Hotels near Lignumvitae Key Botanical State Park

Islander Resort

Islander Resort

4 out of 5
82100 Overseas Highway Islamorada FL
Fully refundableReserve now, pay when you stay
$283 nightly
The price is $318 total per night from Jun 23 to Jun 24
$318 total
Jun 23 - Jun 24
Total with taxes and fees
A private beach, 3 restaurants, and 2 outdoor pools are all featured at this hotel. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Families ...
"Would definitely stay there, again!"

Reviewed on Jun 3, 2026

Opens in a new windowIslander Resort
Cheeca Lodge & Spa

Cheeca Lodge & Spa

5 out of 5
81801 Overseas Highway, Mile Marker 82 Islamorada FL
Fully refundableReserve now, pay when you stay
$336 nightly
The price is $378 total per night from Jun 18 to Jun 19
$378 total
Jun 18 - Jun 19
Total with taxes and fees
This luxury resort features a private beach, a golf course, and a full-service spa. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
"great place to be"

Reviewed on Jun 1, 2026

Opens in a new windowCheeca Lodge & Spa
Chesapeake Beach Resort

Chesapeake Beach Resort

3.5 out of 5
83409 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$238 nightly
The price is $268 total per night from Jun 22 to Jun 23
$268 total
Jun 22 - Jun 23
Total with taxes and fees
A private beach, a marina, and 2 outdoor pools are all featured at this smoke-free hotel. Enjoy a day at the beach kayaking, or relax with sun loungers. Unwind ...
"This place is perfect"

Reviewed on Jun 1, 2026

Opens in a new windowChesapeake Beach Resort
Lime Tree Bay Resort

Lime Tree Bay Resort

3.5 out of 5
68500 Overseas Hwy Long Key FL
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $224 total per night from Jun 14 to Jun 15
$224 total
Jun 14 - Jun 15
Total with taxes and fees
This resort features a private beach, 3 outdoor pools, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy the outdoor ...
"Great staff!! Stunning sunsets! Nice and renovated rooms. Sofabed no so comfy!"

Reviewed on Jun 2, 2026

Opens in a new windowLime Tree Bay Resort
Waterside Suites & Marina

Waterside Suites & Marina

3.5 out of 5
201 Ocean Drive Key Largo FL
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $171 total per night from Jun 4 to Jun 5
$171 total
Jun 4 - Jun 5
Total with taxes and fees
A marina and an outdoor pool are featured at this smoke-free hotel. WiFi in public areas is free. A terrace, a picnic area, and luggage storage are also on ...
"The location is perfect. Being on a marina was fun and made being in the room an experience. The two stories was perfect. The bedroom upstairs helped when my one of us was still sleeping. We had two showers! After swimming we both could come in and shower at the same time. No waiting! The kitchen ..."

Reviewed on Jun 2, 2026

Opens in a new windowWaterside Suites & Marina
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

4 out of 5
84001 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$345 nightly
The price is $388 total per night from Jun 21 to Jun 22
$388 total
Jun 21 - Jun 22
Total with taxes and fees
This Art Deco resort features a private beach, a marina, and 4 restaurants. Enjoy a day at the beach snorkeling, or relax with sun loungers. Families will appreciate ...
"The property was beautiful as soon as we pulled up we were greeted by a woman on a golf cart. She was so happy and helpful. It made us feel comfortable right away, showed us to the front desk and she was also so very friendly. I wish I remembered their names. We got an ocean view. It also overlooked ..."

Reviewed on May 30, 2026

Opens in a new windowThree Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Amara Cay Resort

Amara Cay Resort

4 out of 5
80001 Overseas Hwy Islamorada FL
$256 nightly
The price is $288 total per night from Jun 8 to Jun 9
$288 total
Jun 8 - Jun 9
Total with taxes and fees
A private beach, 2 restaurants, and an outdoor pool are all featured at this resort. If you want to take your pet along, this pet-friendly property offers everything ...
"Muy buen plan en familia para ir a los cayos. Buena atención y limpieza"

Reviewed on Jun 1, 2026

Opens in a new windowAmara Cay Resort
Marina Del Mar Resort and Marina

Marina Del Mar Resort and Marina

2 out of 5
527 Caribbean Drive Key Largo FL
Fully refundableReserve now, pay when you stay
$154 nightly
The price is $174 total per night from Jun 17 to Jun 18
$174 total
Jun 17 - Jun 18
Total with taxes and fees
A marina, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy the gym and perks like free self parking and free WiFi. You'll ...
"Angela was so accommodating and was able to upgrade our stay. Every time we had a question she would have the answers and was very hospitable and welcoming to all of us. The room was clean and beautiful views, quiet and better than we could have imagined. Great location, food and service. We will ..."

Reviewed on Jun 2, 2026

Opens in a new windowMarina Del Mar Resort and Marina
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

4 out of 5
97000 Overseas Hwy Key Largo FL
$302 nightly
The price is $340 total per night from Jun 16 to Jun 17
$340 total
Jun 16 - Jun 17
Total with taxes and fees
A private beach, 2 restaurants, and 2 outdoor pools are all featured at this resort. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
"."

Reviewed on Jun 1, 2026

Opens in a new windowBaker's Cay Resort Key Largo, Curio Collection by Hilton
Don't see what you're looking for?
See all available properties in Lignumvitae Key Botanical State Park
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Lignumvitae Key Botanical State Park hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity