Book Hotels in Lignumvitae Key Botanical State Park, FL
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Top Lignumvitae Key Botanical State Park hotels

Chesapeake Beach Resort
83409 Overseas Hwy, Islamorada, FL
Fully refundableReserve now, pay when you stay
$172 nightly
The price is $194 total per night from Oct 22 to Oct 23
$194 total
Oct 22 - Oct 23
Total with taxes and fees
A private beach, a marina, and 2 outdoor pools are all featured at this smoke-free hotel. Enjoy a day at the beach kayaking, or relax with sun loungers. Unwind ...
"The pools where very clean and very comfy, the place is keep very clean. Thank you."
Reviewed on Oct 13, 2025

Cheeca Lodge & Spa
81801 Overseas Highway, Mile Marker 82, Marker 82, Islamorada, FL
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $224 total per night from Oct 26 to Oct 27
$224 total
Oct 26 - Oct 27
Total with taxes and fees
This luxury resort features a private beach, a golf course, and a full-service spa. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
"Wonderful resort. Would stay again. Dinner was amazing."
Reviewed on Oct 15, 2025

Waterside Suites & Marina
201 Ocean Drive, Key Largo, FL
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $148 total per night from Oct 29 to Oct 30
$148 total
Oct 29 - Oct 30
Total with taxes and fees
A marina and an outdoor pool are featured at this smoke-free hotel. WiFi in public areas is free. A terrace, a picnic area, and luggage storage are also on ...
Love it
"Absolutely loved the hotel. The room was amazing. Great view of the boat cancel"
Reviewed on Oct 11, 2025

Amara Cay Resort
80001 Overseas Hwy, Islamorada, FL
Fully refundableReserve now, pay when you stay
$192 nightly
The price is $217 total per night from Oct 26 to Oct 27
$217 total
Oct 26 - Oct 27
Total with taxes and fees
A private beach, 2 restaurants, and an outdoor pool are all featured at this resort. If you want to take your pet along, this pet-friendly property offers everything ...
"This was our second stay there and will definitely go back. The location is great and there is plenty of well-maintained beach area to enjoy. The room was large, clean and updated. However, the view from the room left a lot to be desired. We booked a standard room so we didn't have expectations one ..."
Reviewed on Oct 14, 2025

Playa Largo Resort & Spa, Autograph Collection
97450 Overseas Highway, Key Largo, FL
Fully refundableReserve now, pay when you stay
$288 nightly
The price is $324 total per night from Oct 26 to Oct 27
$324 total
Oct 26 - Oct 27
Total with taxes and fees
This luxury resort features a full-service spa, a marina, and 3 restaurants. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Enjoy the ...
"Room was clean and spacious. Pools and beach were beautiful."
Reviewed on Oct 11, 2025

Baker's Cay Resort Key Largo, Curio Collection by Hilton
97000 Overseas Hwy, Key Largo, FL
Fully refundableReserve now, pay when you stay
$354 nightly
The price is $398 total per night from Oct 26 to Oct 27
$398 total
Oct 26 - Oct 27
Total with taxes and fees
A private beach, 2 restaurants, and 2 outdoor pools are all featured at this resort. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
"Excellent hotel"
Reviewed on Oct 14, 2025

Marina Del Mar Resort and Marina
527 Caribbean Drive, Key Largo, FL
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $133 total per night from Oct 26 to Oct 27
$133 total
Oct 26 - Oct 27
Total with taxes and fees
A marina, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy the gym and perks like free self parking and free WiFi. You'll ...
Getaway weekend
"The room had an amazing view and the air temperature in the room was very comfortable The staff was super helpful and the room was very clean. We stayed in a two bedroom suite and it was very spacious. We are thinking of returning over the summer"
Reviewed on Oct 13, 2025

Holiday Inn Key Largo by IHG
99701 Overseas Hwy, Key Largo, FL
Fully refundable
$149 nightly
The price is $168 total per night from Oct 21 to Oct 22
$168 total
Oct 21 - Oct 22
Total with taxes and fees
A marina, 2 restaurants, and 2 outdoor pools are all featured at this traditional hotel. Relax with a drink at one of the 2 bars/lounges and enjoy free perks ...
"Awesome trip stayed there for seven days had a blast down by the pool and the tiki hut and the iguanas are fun to watch as are the curly tail lizards no problem we had in the room was the toilet didn’t flush very well. It did flush but it was slow. The restaurant next-door within walking distance ..."
Reviewed on Oct 11, 2025

Hawks Cay Resort
61 Hawks Cay Blvd, Marathon, FL
Fully refundableReserve now, pay when you stay
$326 nightly
The price is $365 total per night from Oct 26 to Oct 27
$365 total
Oct 26 - Oct 27
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...
"Elevator was broken had to carry luggage down steps front desk didn’t tell us rooms were not cleaned daily & forgot to fill coffee keurig with supplies when we checked in, unfortunately garbage was overflowing & needed to request clean towels On the positive side pool/dolphin experience/ kayaks were ..."
Reviewed on Oct 13, 2025
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Lignumvitae Key Botanical State Park with star-rating
Check Lignumvitae Key Botanical State Park Hotels by Star Rating

5 Star Hotels
3 properties
Recent Lignumvitae Key Botanical State Park hotel reviews by fellow wanderers

Cheeca Lodge & Spa
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Wonderful resort. Would stay again. Dinner was amazing. "
A verified traveler stayed at Cheeca Lodge & Spa
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