Explore 12 Luxury Hotels in Florence
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Best Luxury Hotels in Florence
The Mantissa Hotel
130 East Carolina Ave, Hartsville, SC
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $170 total per night from Aug 4 to Aug 5
$170 total
Aug 4 - Aug 5
Total includes taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Enjoy the a rooftop terrace and free perks like on-the-go breakfast and free self parking. A business ...
9/10 Wonderful! (245 reviews)
"I love the stay it was amazing. This place did not disappoint."
Reviewed on Jul 5, 2025
Hotel Florence, Tapestry Collection by Hilton
126 W Evans St, Florence, SC
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $144 total per night from Aug 3 to Aug 4
$144 total
Aug 3 - Aug 4
Total includes taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
8.8/10 Excellent! (576 reviews)
"What an amazing hotel right in downtown Florence. The atmosphere was perfect, the hotel was so unique, very clean and very safe. Will definitely be returning!"
Reviewed on Jul 26, 2025
Red Roof Inn Florence - Civic Center
2690 David H McLeod Boulevard, Florence, SC
Fully refundableReserve now, pay when you stay
$56 nightly
The price is $63 total per night from Jul 30 to Jul 31
$63 total
Jul 30 - Jul 31
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...
6.8/10 (1,008 reviews)
"Ok place for a nights sleep when weary from the road."
Reviewed on Jul 24, 2025
Days Inn by Wyndham Florence/I-95 North
2111 West Lucas St/I-95, I-95 & Hwy 52 Exit 164, Florence, SC
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $69 total per night from Aug 10 to Aug 11
$69 total
Aug 10 - Aug 11
Total includes taxes and fees
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this motel. Guests will appreciate free perks like on-the-go breakfast and ...
6.6/10 (1,006 reviews)
"Dated… but clean… could use a DEEP clean.. hair dryer must have been dropped and had a big piece missing. Someone could get hurt. Full breakfast was a joke… boiled eggs waffles…. But no water to drink… I felt safe so that’s a plus!"
Reviewed on Jul 7, 2025
Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr, Florence, SC
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $66 total per night from Jul 29 to Jul 30
$66 total
Jul 29 - Jul 30
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
6.6/10 (1,012 reviews)
"I would reserve again, but my wife has her own opinion."
Reviewed on Jul 20, 2025
Days Inn by Wyndham Dillon
823 Radford Blvd, Dillon, SC
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like on-the-go breakfast and ...
5.4/10 (814 reviews)
"Nice for last minute get away."
Reviewed on Jul 15, 2025
Clarion Inn & Suites
1819 West Lucas Street, Building A, Florence, SC
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $64 total per night from Aug 4 to Aug 5
$64 total
Aug 4 - Aug 5
Total includes taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Enjoy the seasonal outdoor pool and free perks like buffet breakfast and free self parking. A business ...
4.2/10 (274 reviews)
"They took a $100 deposit and haven't returned it"
Reviewed on Jun 7, 2025
Baymont Inn & Suites Florence by Wyndham
1826 W Lucas Street, Florence, SC
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self ...
"Still in Renovation mode"
Reviewed on Sep 3, 2024
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Florence Luxury Hotels
Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Florence luxury hotels are the plush oasis you’ve been looking for.
Choose from the best luxury hotels in Florence to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.
We want you to enjoy your next vacation in style and the top luxury resorts in Florence will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Florence, and plan your next opulent escape.
Florence hotels essential information
Accommodation | 333 hotels |
|---|---|
Lowest Price | $63 |
Highest Price | $170 |
Popular hotels | The Mantissa Hotel, Days Inn by Wyndham Dillon, Hotel Florence, Tapestry Collection by Hilton, Days Inn by Wyndham Florence/I-95 North, Baymont Inn & Suites Florence by Wyndham, Clarion Inn & Suites, Red Roof Inn Florence - Civic Center, Days Inn by Wyndham Florence Near Civic Center |
Popular Luxury Stays in Florence
Recent Florence Hotel Reviews By Fellow Wanderers
Quality Inn & Suites Florence Civic Center
5 out of 5
Posted 6 days ago
Travelocity Verified Review
"Great place to rest and sleep after 11 hrs of driving. "
A verified traveler stayed at Quality Inn & Suites Florence Civic Center
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