Explore 2 Luxury Hotels in Houston Museum District

Name: Hotel Zaza Houston Museum District
Price range: $329 total
Rating: 8.8

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Best Luxury Hotels in Houston Museum District

Hotel Zaza Houston Museum District

5701 Main Street, Houston, TX

Fully refundableReserve now, pay when you stay

$281 nightly

$329 total

Oct 25 - Oct 26

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury aparthotel. Traveling on business? Take advantage of the 24-hour business ...

8.8/10 Excellent! (1,795 reviews)

"Did not get fruit plate amenity despite several requests both pre and during stay. Shuttle service left us stranded. View from one of rooms was bleak."

Reviewed on Oct 15, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Houston Museum District

Hilton Americas-Houston

1600 Lamar Street, Houston, TX

$188 nightly

$220 total

Oct 24 - Oct 25

Total with taxes and fees

9.2/10 Wonderful! (1,529 reviews)

5 star hotels in Houston Museum District

The Post Oak Hotel at Uptown Houston

1600 West Loop South, Houston, TX

$490 nightly

$574 total

Nov 17 - Nov 18

Total with taxes and fees

9.6/10 Exceptional! (836 reviews)

Houston Museum District Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Houston Museum District luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Houston Museum District to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Houston Museum District will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Houston Museum District, and plan your next opulent escape.