Book Hotels in Central San Diego, CA

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Central San Diego hotels

Lafayette Hotel & Club

Lafayette Hotel & Club

4 out of 5
2223 El Cajon Blvd San Diego CA
Fully refundableReserve now, pay when you stay
$226 nightly
The price is $259 total per night from Dec 11 to Dec 12
$259 total
Dec 11 - Dec 12
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...
Very hip place to stay with lobby bars always hopping. Rooms were cute and nice neighborhood.

Reviewed on Dec 1, 2025

Opens in a new windowLafayette Hotel & Club
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $175 total per night from Dec 14 to Dec 15
$175 total
Dec 14 - Dec 15
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
The room was very clean.

Reviewed on Dec 1, 2025

Opens in a new windowLegacy Resort Hotel & Spa
Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla

4 out of 5
4550 La Jolla Village Dr San Diego CA
Fully refundableReserve now, pay when you stay
$151 nightly
The price is $174 total per night from Dec 18 to Dec 19
$174 total
Dec 18 - Dec 19
Total with taxes and fees
This traditional hotel includes 2 restaurants, an indoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and WiFi in ...
Easy check-in and great location for my business. Breakfast was solid and included - always a plus when you're travelling!

Reviewed on Dec 3, 2025

Opens in a new windowEmbassy Suites by Hilton San Diego La Jolla
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S San Diego CA
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $86 total per night from Dec 17 to Dec 18
$86 total
Dec 17 - Dec 18
Total with taxes and fees
This Art Deco hotel includes 2 restaurants, an outdoor pool, and a hot tub. Enjoy the gym and perks like free WiFi. A bar/lounge, a 24-hour front desk, and a ...
good

Reviewed on Dec 8, 2025

Opens in a new windowKings Inn San Diego
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

2.5 out of 5
2151 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $111 total per night from Jan 4 to Jan 5
$111 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Room was clean,buffet bkfast was good,staff were friendly & helpful!

Reviewed on Dec 10, 2025

Opens in a new windowHampton Inn San Diego/Mission Valley
Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

4 out of 5
1433 Camino Del Rio S San Diego CA
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $136 total per night from Dec 14 to Dec 15
$136 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Decent room, great staff and close to am

Reviewed on Dec 6, 2025

Opens in a new windowSheraton Mission Valley San Diego Hotel
San Diego Marriott La Jolla

San Diego Marriott La Jolla

4 out of 5
4240 La Jolla Village Dr La Jolla CA
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $178 total per night from Dec 12 to Dec 13
$178 total
Dec 12 - Dec 13
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Great convenient spot away from all the traffic madness of the village. Thomas at the front desk was outstanding. $40 parking and $40 breakfasts was ridiculous!

Reviewed on Dec 8, 2025

Opens in a new windowSan Diego Marriott La Jolla
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S San Diego CA
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $136 total per night from Dec 16 to Dec 17
$136 total
Dec 16 - Dec 17
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Great hotel! Close to a lot of shopping. Would stay again.

Reviewed on Dec 10, 2025

Opens in a new windowHilton San Diego Mission Valley
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $102 total per night from Dec 14 to Dec 15
$102 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...
WiFi was very slow.

Reviewed on Dec 9, 2025

Opens in a new windowDays Inn by Wyndham San Diego Hotel Circle
Don't see what you're looking for?
See all available properties in Central San Diego
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Central San Diego hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Central San Diego Hotel & Travel Guide\n

You can discover a wide variety of apartment and hotel options to choose from in Central San Diego. Travelocity's booking page currently is where you will find 51 hotel establishments within a 6-mile (10-kilometer) distance of downtown Central San Diego.

You'll find Residence Inn By Marriott San Diego Central and Hampton Inn San Diego-Kearny Mesa within wandering distance of Central San Diego's city center.

Students, families and those watching their dollars will find some great Central San Diego accommodation options that won't blow holes in the wallet. The Extended Stay America San Diego - Mission Valley - Stadium and the Quality Inn San Diego Miramar are amongst the other cheaper hotels worth investigating.

The Rancho Valencia Resort and Spa is located 10 miles (16 kilometers) away from central Central San Diego. Another place to stay is the Fairmont Grand Del Mar, which is 7 miles (11 kilometers) away. The Hotel del Coronado along with the Pantai Inn are alternate bases around Central San Diego.

If time is on your side, why not broaden your horizons and get to know the many other attractions around Southern California during your stay in the area? Southern California offers beaches, mountains and rolling hills, and interesting tourist places of interest are art galleries, open-air exhibits and street art. Modern visitors in this part of United States of America commonly enjoy snowboarding.

Looking for more activities? Consider spending a few hours enjoying Centennial Park and Coronado Ferry Landing, which you'll find in Coronado, 13 miles (21 kilometers) south of Central San Diego. The Marriott Coronado Island Resort & Spa and Hard Rock Hotel San Diego are just some examples of the apartment and hotel choices in Coronado. Or stay in Carlsbad, 20 miles (34 kilometers) to the northwest of Central San Diego, where you can choose between the Four Seasons Residence Club Aviara, North San Diego and Park Hyatt Aviara Resort, Spa & Golf Club. Whether you're just passing through or staying in Carlsbad, set aside some time to visit the Carlsbad Premium Outlets and Carlsbad State Beach.

San Diego International Airport is a practical gateway for air travel, and can be found 9 miles (15 kilometers) away from downtown Central San Diego. Conveniently located Travelocity-listed hotels include Paradise Point Resort & Spa and San Diego Marriott Gaslamp Quarter.

Recent Central San Diego hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity