Explore 9 Luxury Hotels in West Main Historic District

Name: Hampton Inn Louisville Downtown
Price range: $109 total
Rating: 8.2

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Best Luxury Hotels in West Main Historic District

21c Museum Hotel Louisville

700 W Main Street, Louisville, KY

Fully refundableReserve now, pay when you stay

$125 nightly

$147 total

Aug 11 - Aug 12

Total includes taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

9.2/10 Wonderful! (1,001 reviews)

"Great Location. Great hotel. Great team members."

Reviewed on Jul 14, 2025

Louisville Marriott Downtown

280 West Jefferson Street, Louisville, KY

Fully refundableReserve now, pay when you stay

$159 nightly

$187 total

Aug 1 - Aug 2

Total includes taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

9/10 Wonderful! (1,002 reviews)

"Very clean."

Reviewed on Jul 13, 2025

Galt House Hotel Trademark Collection by Wyndham

140 North Fourth Street, Louisville, KY

$140 nightly

$164 total

Aug 10 - Aug 11

Total includes taxes and fees

A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...

8.8/10 Excellent! (3,438 reviews)

"Great Location and was clean throughout"

Reviewed on Jul 16, 2025

Embassy Suites Louisville Downtown

501 South Fourth Street, Louisville, KY

$118 nightly

$139 total

Aug 3 - Aug 4

Total includes taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and WiFi in public areas. Valet ...

8.8/10 Excellent! (1,018 reviews)

"Great location and beautiful hotel with happy hour and breakfast included! Family friendly!"

Reviewed on Jul 17, 2025

Seelbach Hilton Louisville Downtown

500 S 4th St, Louisville, KY

Fully refundableReserve now, pay when you stay

$168 nightly

$198 total

Jul 21 - Jul 22

Total includes taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, express check-out, and ...

8.6/10 Excellent! (1,001 reviews)

Wedding weekend

"Charming beautiful hotel . Excellent location to walk to all attractions."

Reviewed on Jul 13, 2025

Hyatt Regency Louisville

320 West Jefferson Street, Louisville, KY

Fully refundableReserve now, pay when you stay

$127 nightly

$149 total

Aug 9 - Aug 10

Total includes taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

8.6/10 Excellent! (1,003 reviews)

"Good"

Reviewed on Jul 17, 2025

Hampton Inn Louisville Downtown

101 E Jefferson St, Louisville, KY

Fully refundableReserve now, pay when you stay

$93 nightly

$109 total

Jul 27 - Jul 28

Total includes taxes and fees

This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Relax ...

8.2/10 Very Good! (1,014 reviews)

"Loved the hotel and the property. Not much retail around a very business setting which was fine for the night. Comfortable beds and very clean room."

Reviewed on Jul 13, 2025

Econo Lodge Downtown Louisville

401 S 2nd St, Louisville, KY

Fully refundableReserve now, pay when you stay

$58 nightly

$69 total

Aug 12 - Aug 13

Total includes taxes and fees

This motel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the express check-out. ...

7.2/10 Good! (1,002 reviews)

"Perfect affordable place to stay! It is such a convenient location within walking distance of many nearby businesses, friendly staff, clean room with a BALCONY that I was not expecting. Noisy road is my only complaint, and that’s the price you pay for being so close to everything, so it’s worth it ..."

Reviewed on Jul 7, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in West Main Historic District

Stellar Suites

822 E Market St, Louisville, KY

$159 nightly

$185 total

Aug 4 - Aug 5

Total includes taxes and fees

9.6/10 Exceptional! (99 reviews)

5 star hotels in West Main Historic District

Louisville Bourbon Inn

1332 S 4th St, Louisville, KY

$265 nightly

$308 total

Jul 20 - Jul 21

Total includes taxes and fees

10/10 Exceptional! (16 reviews)

West Main Historic District Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the West Main Historic District luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in West Main Historic District to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in West Main Historic District will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in West Main Historic District, and plan your next opulent escape.

West Main Historic District hotels essential information

Accommodation	1,998 hotels
Lowest Price	$69
Highest Price	$308
Popular hotels	21c Museum Hotel Louisville, Galt House Hotel Trademark Collection by Wyndham, Embassy Suites Louisville Downtown, Econo Lodge Downtown Louisville, Seelbach Hilton Louisville Downtown, Louisville Marriott Downtown, Hyatt Regency Louisville, Hampton Inn Louisville Downtown