Find & compare boutique hotels in South Carolina Midlands, SC from $84

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Top South Carolina Midlands Boutique Hotels

Graduate by Hilton Columbia SC

Graduate by Hilton Columbia SC

4 out of 5
1619 Pendleton Street, Columbia, SC
Free Cancellation
Reserve now, pay when you stay
$131 nightly
The price is $147 total per night
$147 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free internet in ...
Inn on the Square, Ascend Hotel Collection

Inn on the Square, Ascend Hotel Collection

3 out of 5
104 Court Avenue East, Greenwood, SC
Free Cancellation
Reserve now, pay when you stay
$118 nightly
The price is $131 total per night
$131 total
Sep 7 - Sep 8
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the free WiFi in public areas and onsite conference center. ...
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

3 out of 5
126 W Evans St, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$132 nightly
The price is $147 total per night
$147 total
Sep 7 - Sep 8
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
Quality Inn Kingstree

Quality Inn Kingstree

2.5 out of 5
1610 N Longstreet St, Kingstree, SC
Free Cancellation
Reserve now, pay when you stay
$76 nightly
The price is $84 total per night
$84 total
Sep 23 - Sep 24
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the business center. A restaurant, ...
The Inn at the Crossroads

The Inn at the Crossroads

2 out of 5
128 West Main Street, Lake City, SC
Free Cancellation
Reserve now, pay when you stay
$118 nightly
The price is $133 total per night
$133 total
Sep 3 - Sep 4
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
The Mantissa Hotel

The Mantissa Hotel

3 out of 5
130 East Carolina Ave, Hartsville, SC
Free Cancellation
Reserve now, pay when you stay
$162 nightly
The price is $181 total per night
$181 total
Sep 1 - Sep 2
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Enjoy the a rooftop terrace and free perks like on-the-go breakfast and free self parking. A business ...
Hyatt Place Columbia/Downtown/The Vista

Hyatt Place Columbia/Downtown/The Vista

3 out of 5
819 Gervais Street, Columbia, SC
Free Cancellation
Reserve now, pay when you stay
$123 nightly
The price is $138 total per night
$138 total
Sep 14 - Sep 15
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
Sheraton Columbia Downtown Hotel

Sheraton Columbia Downtown Hotel

3.5 out of 5
1400 Main St, Columbia, SC
Free Cancellation
Reserve now, pay when you stay
$107 nightly
The price is $120 total per night
$120 total
Sep 15 - Sep 16
Total with taxes and fees
This hotel features 2 bars/lounges and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. ...
Lookaway Inn

Lookaway Inn

2.5 out of 5
103 W Forest Ave, North Augusta, SC
$149 nightly
The price is $167 total per night
$167 total
Aug 29 - Aug 30
Total with taxes and fees
This bed & breakfast doesn't skimp on freebies - guests receive free WiFi and free self parking. A terrace, a garden, and free newspapers are also on offer.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Boutique Hotels in South Carolina Midlands

Boutique hotels vary from charming and romantic to artistic and just plain quirky. The one thing they typically have in common is delivering an upscale, intimate vibe with personalized service and ultimate comfort. For the refined traveler or those looking for that special something, boutique lodging is a great combination of both individualized and traditional amenities. Let your imagination run wild, then turn to Travelocity to help you find the best boutique hotels in South Carolina Midlands.

Sample the local cuisine, tour the sights, or enjoy a night on the town—then retire to your room, which likely has high-quality linens, luxurious bath products, and custom furniture. Perhaps you’ll sip cocktails or listen to live music at a social event, where you can mingle with other guests in a hip yet casual setting, like the library. Or simply admire the ambiance of the design, lighting, art, and architecture—as unique as the guests themselves in many South Carolina Midlands boutique hotels.

Explore the boutique hotels in South Carolina Midlands to discover your perfect match, then get ready for a memorable and authentic escapade. In just a few minutes, you can reserve a vacation with all the right touches. Book with Travelocity today for the best prices and customer service.

South Carolina Midlands hotels essential information

Accommodation
2,922 hotels
Lowest Price
$84
Highest Price
$181
Popular hotels
Hotel Florence, Tapestry Collection by Hilton, The Inn at the Crossroads, The Mantissa Hotel, Inn on the Square, Ascend Hotel Collection, Graduate by Hilton Columbia SC, Hyatt Place Columbia/Downtown/The Vista, Sheraton Columbia Downtown Hotel, Lookaway Inn, Quality Inn Kingstree