Explore top 2025 5 Star Hotels in Gulf of Mexico

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Top Gulf of Mexico 5 Star hotels

The Roosevelt New Orleans, A Waldorf Astoria Hotel

The Roosevelt New Orleans, A Waldorf Astoria Hotel

5 out of 5
130 Roosevelt Way, New Orleans, LA
Fully refundableReserve now, pay when you stay
$235 nightly
The price is $277 total per night from Oct 27 to Oct 28
$277 total
Oct 27 - Oct 28
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9.2/10 Wonderful! (1,016 reviews)
"The hotel was beautiful and the staff was amazing!"

Reviewed on Sep 25, 2025

Opens in a new windowThe Roosevelt New Orleans, A Waldorf Astoria Hotel
Four Seasons Hotel New Orleans

Four Seasons Hotel New Orleans

5 out of 5
2 Canal Street, New Orleans, LA
Fully refundableReserve now, pay when you stay
$440 nightly
The price is $516 total per night from Oct 5 to Oct 6
$516 total
Oct 5 - Oct 6
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, laundry ...
9.4/10 Exceptional! (563 reviews)
"Wonderful hotel and staff. The rooms are beautiful, the beds are comfortable, and the location is perfect. The only drawback is that its located next to train tracks where there are active trains (that blow their horns!)"

Reviewed on Sep 22, 2025

Opens in a new windowFour Seasons Hotel New Orleans
The Tampa EDITION

The Tampa EDITION

5 out of 5
500 Channelside Dr., Tampa, FL
Fully refundableReserve now, pay when you stay
$399 nightly
The price is $453 total per night from Oct 13 to Oct 14
$453 total
Oct 13 - Oct 14
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this luxury hotel. Relax with a drink at one of the 4 bars/lounges and get perks like ...
9.2/10 Wonderful! (292 reviews)
"I recently stayed at The Edition Tampa and was thoroughly impressed. This hotel truly lives up to its 5-star reputation. From the moment I arrived, the staff were warm, attentive, and incredibly professional, making me feel welcome throughout my stay. The highlight for me was definitely the pool ..."

Reviewed on Sep 19, 2025

Opens in a new windowThe Tampa EDITION
The Ritz-Carlton, New Orleans

The Ritz-Carlton, New Orleans

5 out of 5
921 Canal St, New Orleans, LA
Fully refundableReserve now, pay when you stay
$339 nightly
The price is $398 total per night from Oct 5 to Oct 6
$398 total
Oct 5 - Oct 6
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9.2/10 Wonderful! (1,013 reviews)
"Entire staff were all very kind & professional. Beautiful hotel, comfortable suite & delicious food at every meal! Great job all the way around👍"

Reviewed on Sep 22, 2025

Opens in a new windowThe Ritz-Carlton, New Orleans
Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

5 out of 5
1 Knights Key Boulevard, MM 47, Marathon, FL
Fully refundableReserve now, pay when you stay
$306 nightly
The price is $344 total per night from Sep 28 to Sep 29
$344 total
Sep 28 - Sep 29
Total with taxes and fees
This smoke-free hotel features a full-service spa, 5 outdoor pools, and a restaurant. Spend a day at the beach scuba diving, or relax with sun loungers and beach ...
9/10 Wonderful! (1,063 reviews)
"Exellent place to relax."

Reviewed on Sep 21, 2025

Opens in a new windowIsla Bella Beach Resort & Spa
The Windsor Court

The Windsor Court

5 out of 5
300 Gravier St, New Orleans, LA
Fully refundableReserve now, pay when you stay
$427 nightly
The price is $500 total per night from Sep 28 to Sep 29
$500 total
Sep 28 - Sep 29
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...
9.6/10 Exceptional! (1,001 reviews)
"Five star experience from check-in to check-out"

Reviewed on Sep 14, 2025

Opens in a new windowThe Windsor Court
The Henderson Beach Resort & Spa

The Henderson Beach Resort & Spa

5 out of 5
200 Henderson Resort Way, Destin, FL
Fully refundableReserve now, pay when you stay
$398 nightly
The price is $450 total per night from Sep 28 to Sep 29
$450 total
Sep 28 - Sep 29
Total with taxes and fees
A full-service spa, 4 restaurants, and 2 outdoor pools are all featured at this smoke-free resort. Relax with sun loungers and beach umbrellas, and cool off ...
9.2/10 Wonderful! (1,014 reviews)
"We had an incredible view from our hotel room and the hotel had endless things to do. Absolutely beautiful place to stay and only wish we could have stayed for longer."

Reviewed on Sep 21, 2025

Opens in a new windowThe Henderson Beach Resort & Spa
The Ritz-Carlton, Sarasota

The Ritz-Carlton, Sarasota

5 out of 5
1111 Ritz Carlton Dr, Sarasota, FL
Fully refundableReserve now, pay when you stay
$607 nightly
The price is $685 total per night from Sep 28 to Sep 29
$685 total
Sep 28 - Sep 29
Total with taxes and fees
This smoke-free hotel features a golf course, a full-service spa, and a marina. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Enjoy ...
9/10 Wonderful! (1,004 reviews)
"Love"

Reviewed on Sep 7, 2025

Opens in a new windowThe Ritz-Carlton, Sarasota
Maison Métier, in the Unbound Collection by Hyatt

Maison Métier, in the Unbound Collection by Hyatt

5 out of 5
546 Carondelet Street, New Orleans, LA
Fully refundableReserve now, pay when you stay
$322 nightly
The price is $377 total per night from Sep 28 to Sep 29
$377 total
Sep 28 - Sep 29
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, dry cleaning, and luggage storage are also offered.
9.8/10 Exceptional! (246 reviews)
"Absolutely loved this property and the entire team working there. It was such an amazing experience all-around!"

Reviewed on Sep 18, 2025

Opens in a new windowMaison Métier, in the Unbound Collection by Hyatt
Bahama Breeze

Bahama Breeze

5 out of 5
618 Evergreen St, Panama City Beach, FL
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $110 total per night from Sep 29 to Sep 30
$110 total
Sep 29 - Sep 30
Total with taxes and fees
An outdoor pool, free self parking, and barbecue grills are featured at this motel. A picnic area is also provided.
7.4/10 Good! (99 reviews)
"The room was very comfortable, quiet and great location! However, no ice machine on the property, no lights at night time for safety and the air conditioners are very loud. The WiFi is very spotty."

Reviewed on Jul 21, 2025

Opens in a new windowBahama Breeze
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Gulf of Mexico Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Gulf of Mexico to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Gulf of Mexico 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Gulf of Mexico before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Gulf of Mexico hotel reviews by fellow wanderers