Explore top 2026 5 Star Hotels in Gulf of Mexico
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Top Gulf of Mexico 5 Star hotels
The Roosevelt New Orleans, A Waldorf Astoria Hotel
130 Roosevelt Way New Orleans LA
Fully refundableReserve now, pay when you stay
$247 nightly
The price is $293 total per night from Mar 22 to Mar 23
$293 total
Mar 22 - Mar 23
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9.2/10 Wonderful! (1,003 reviews)
We had a great stay!
Reviewed on Feb 28, 2026
The Windsor Court
300 Gravier St New Orleans LA
Fully refundableReserve now, pay when you stay
$365 nightly
The price is $431 total per night from Mar 8 to Mar 9
$431 total
Mar 8 - Mar 9
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...
9.8/10 Exceptional! (1,003 reviews)
Cool atmosphere
Reviewed on Feb 26, 2026
The Tampa EDITION
500 Channelside Dr. Tampa FL
Fully refundableReserve now, pay when you stay
$394 nightly
The price is $447 total per night from Mar 29 to Mar 30
$447 total
Mar 29 - Mar 30
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this luxury hotel. Relax with a drink at one of the 4 bars/lounges and get perks like ...
9.4/10 Exceptional! (347 reviews)
Very convenient
Reviewed on Feb 23, 2026
Cheeca Lodge & Spa
81801 Overseas Highway, Mile Marker 82 Islamorada FL
Fully refundableReserve now, pay when you stay
$529 nightly
The price is $596 total per night from Mar 2 to Mar 3
$596 total
Mar 2 - Mar 3
Total with taxes and fees
This luxury resort features a private beach, a golf course, and a full-service spa. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
9.2/10 Wonderful! (1,298 reviews)
This Resort is unbelievable from the rooms to the beach, walking & biking trails, golf course 27 acres of lush property. Lots of shops & restaurants nearby including Bass Pro Shop, small artists shops & brewery within walking/biking distance.
Reviewed on Feb 25, 2026
Four Seasons Hotel New Orleans
2 Canal Street New Orleans LA
Fully refundableReserve now, pay when you stay
$460 nightly
The price is $543 total per night from Mar 8 to Mar 9
$543 total
Mar 8 - Mar 9
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, laundry ...
Isla Bella Beach Resort & Spa
1 Knights Key Boulevard Marathon FL
Fully refundableReserve now, pay when you stay
$660 nightly
The price is $743 total per night from Mar 3 to Mar 4
$743 total
Mar 3 - Mar 4
Total with taxes and fees
This smoke-free hotel features a full-service spa, 5 outdoor pools, and a restaurant. Spend a day at the beach scuba diving, or relax with sun loungers and beach ...
9.2/10 Wonderful! (1,096 reviews)
Front desk staff and wait staff were great! We stayed on our way to key west and on the way back we decided to stay again. In fact as we were getting ready to leave, we couldn’t think of a reason not to stay just one more night. So we ended up staying there three nights of our five night trip. The ...
Reviewed on Feb 27, 2026
Maison Métier, in the Unbound Collection by Hyatt
546 Carondelet Street New Orleans LA
Fully refundableReserve now, pay when you stay
$449 nightly
The price is $528 total per night from Mar 8 to Mar 9
$528 total
Mar 8 - Mar 9
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, dry cleaning, and luggage storage are also offered.
9.8/10 Exceptional! (276 reviews)
This hotel is beyond beautiful, and the staff are EXCELLENT. Everyone was kind, attentive, helpful, and professional. This is the best hotel I've every stayed at! My husband and I went for our honeymoon -- it was nice to visit the sites and then stay here in the Business district. It was easy to ...
Reviewed on Feb 5, 2026
The Henderson Beach Resort & Spa
200 Henderson Resort Way Destin FL
$378 nightly
The price is $427 total per night from Mar 2 to Mar 3
$427 total
Mar 2 - Mar 3
Total with taxes and fees
A full-service spa, 4 restaurants, and 2 outdoor pools are all featured at this smoke-free resort. Relax with sun loungers and beach umbrellas, and cool off ...
9.2/10 Wonderful! (1,000 reviews)
All around great resort for any occasion!!!
Reviewed on Feb 23, 2026
The Ritz-Carlton, Sarasota
1111 Ritz Carlton Dr Sarasota FL
Fully refundableReserve now, pay when you stay
$907 nightly
The price is $1,025 total per night from Mar 30 to Mar 31
$1,025 total
Mar 30 - Mar 31
Total with taxes and fees
This smoke-free hotel features a golf course, a full-service spa, and a marina. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Enjoy ...
9.2/10 Wonderful! (1,001 reviews)
Staff were very friendly and helpful. Valet parking staff was extremely accomodating. Loved the ocean club. Bar was wonderful. Beach was great. Amenities were fantastic. Room was somewhat dated but very clean.
Reviewed on Feb 22, 2026
The Ritz-Carlton, New Orleans
921 Canal St New Orleans LA
$341 nightly
The price is $403 total per night from Mar 8 to Mar 9
$403 total
Mar 8 - Mar 9
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9.2/10 Wonderful! (1,001 reviews)
Room was small and over looked a roof parking area thought the could have done better on the room for the price we paid
Reviewed on Feb 27, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Gulf of Mexico Resorts & 5 Star Hotels
Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Gulf of Mexico to make sure your trip is as extravagantly comfortable as you expect.
Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!
Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.
For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Gulf of Mexico 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.
Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Gulf of Mexico before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.
Recent Gulf of Mexico hotel reviews by fellow wanderers
The Pensacola Beach Resort
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Beautiful hotel! Very clean and friendly! "
A verified traveler from Fruitland stayed at The Pensacola Beach Resort
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