Explore top 2026 5 Star Hotels in Gulf of Mexico

Name: The Mayfair
Price range: $321 total

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Top Gulf of Mexico 5 Star hotels

The Roosevelt New Orleans, A Waldorf Astoria Hotel

130 Roosevelt Way New Orleans LA

Fully refundableReserve now, pay when you stay

$221 nightly

$261 total

Sep 20 - Sep 21

Total with taxes and fees

A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

9.4/10 Exceptional! (1,006 reviews)

"Enjoyed my stay Staff was friendly great location"

Reviewed on Sep 12, 2026

The Windsor Court

300 Gravier St New Orleans LA

$334 nightly

$394 total

Sep 20 - Sep 21

Total with taxes and fees

A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...

9.8/10 Exceptional! (1,001 reviews)

"I travel with my dog. It’s important to me that he is happy and comfortable. Windsor Court makes this priority for them as well. I love that. I’m very grateful for them."

Reviewed on Sep 11, 2026

Four Seasons Hotel New Orleans

2 Canal Street New Orleans LA

Fully refundableReserve now, pay when you stay

$440 nightly

$519 total

Sep 20 - Sep 21

Total with taxes and fees

A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, laundry ...

9.6/10 Exceptional! (732 reviews)

"Best hotel in New Orleans Great vibes at the Chandelier Bar Top notch service from hotel staff - in particular Noah at reception and Joshua at the Chandelier Bar Location right across from casino an added plus :)"

Reviewed on Sep 12, 2026

Isla Bella Beach Resort & Spa

1 Knights Key Boulevard Marathon FL

Fully refundableReserve now, pay when you stay

$252 nightly

$283 total

Sep 13 - Sep 14

Total with taxes and fees

This smoke-free hotel features a full-service spa, 5 outdoor pools, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi ...

9.2/10 Wonderful! (1,263 reviews)

"Room was clean Staff was nice Loved our stay"

Reviewed on Sep 12, 2026

The Ritz-Carlton, New Orleans

921 Canal St New Orleans LA

Fully refundableReserve now, pay when you stay

$258 nightly

$305 total

Sep 20 - Sep 21

Total with taxes and fees

A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

The Henderson Beach Resort & Spa

200 Henderson Resort Way Destin FL

Fully refundableReserve now, pay when you stay

$332 nightly

$375 total

Sep 13 - Sep 14

Total with taxes and fees

A full-service spa, 4 restaurants, and 2 outdoor pools are all featured at this luxury resort. There's fun for all ages with a lazy river and a children's pool, ...

9.2/10 Wonderful! (1,008 reviews)

"Amazing!!"

Reviewed on Sep 12, 2026

The Ritz-Carlton, Sarasota

1111 Ritz Carlton Dr Sarasota FL

Fully refundableReserve now, pay when you stay

$592 nightly

$669 total

Oct 12 - Oct 13

Total with taxes and fees

This smoke-free hotel features a golf course, a full-service spa, and a marina. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Enjoy ...

9.2/10 Wonderful! (1,019 reviews)

"The staff is polite and helpful. The hotel and beach club are beautiful but need a bit of maintenance.... New paint, new carpet, updated showers, better quality shampoo, conditioner, etc ...."

Reviewed on Sep 12, 2026

The Tampa EDITION

500 Channelside Dr. Tampa FL

Fully refundableReserve now, pay when you stay

$389 nightly

$443 total

Sep 14 - Sep 15

Total with taxes and fees

A full-service spa, 3 restaurants, and an outdoor pool are all featured at this luxury hotel. Relax with a drink at one of the 4 bars/lounges and get perks like ...

9.4/10 Exceptional! (424 reviews)

"I don't usually write reviews about my stays, however this hotel was exceptional. The staff was extremely attentive. They provided shuttle services to convenient places within a 2mile radius. They also surprised us with a complimentary bottle of champagne..but by far the best surprise was when we ..."

Reviewed on Sep 8, 2026

Maison Métier, in the Unbound Collection by Hyatt

546 Carondelet Street New Orleans LA

Fully refundableReserve now, pay when you stay

$374 nightly

$440 total

Sep 20 - Sep 21

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, dry cleaning, and luggage storage are also offered.

The Mayfair

1011 Canal St New Orleans LA

$279 nightly

$321 total

Sep 13 - Sep 14

Total with taxes and fees

A restaurant and a rooftop terrace are featured at this aparthotel. WiFi in public areas is free. Self parking, express check-out, and luggage storage are also ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Gulf of Mexico Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Gulf of Mexico to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Gulf of Mexico 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Gulf of Mexico before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.