Explore top 2026 4 Star Hotels in Panama Canal Zone

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Top Panama Canal Zone 4 Star hotels

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
$108 nightly
The price is $119 total per night from Mar 23 to Mar 24
$119 total
Mar 23 - Mar 24
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 3 restaurants. Families will appreciate the children's pool, onsite laundry facilities, and ...
7.8/10 Good! (1,015 reviews)
Pool area was restful..

Reviewed on Mar 9, 2026

Opens in a new windowHotel El Panama by Faranda Grand, a member of Radisson Individuals
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate the children's pool, onsite laundry facilities, and babysitting. ...
8.6/10 Excellent! (2,489 reviews)
Good hotel to stay at when you have an early morning flight

Reviewed on Mar 10, 2026

Opens in a new windowCrowne Plaza Panama Airport by IHG
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $148 total per night from Apr 3 to Apr 4
$148 total
Apr 3 - Apr 4
Total with taxes and fees
A full-service spa, 3 restaurants, and 3 outdoor tennis courts are all featured at this smoke-free resort. Families will appreciate the playground, kid-friendly ...
8.6/10 Excellent! (1,008 reviews)
Clean and comfortable room. Bathroom needs an overall. Faucets are hard to open and close.

Reviewed on Mar 7, 2026

Opens in a new windowSheraton Grand Panama
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
Fully refundableReserve now, pay when you stay
$158 nightly
The price is $174 total per night from Apr 5 to Apr 6
$174 total
Apr 5 - Apr 6
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center ...
9/10 Wonderful! (1,017 reviews)
I could hear the traffic like I was standing outside The toilet keep running,

Reviewed on Mar 9, 2026

Opens in a new windowLas Americas Golden Tower Panama
Marriott Panama Hotel

Marriott Panama Hotel

4 out of 5
Roosevelt Ave., Allbrook Mall Panama City Panama
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $167 total per night from Mar 27 to Mar 28
$167 total
Mar 27 - Mar 28
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in ...
9/10 Wonderful! (1,008 reviews)
Front staff were so helpful and friendly.

Reviewed on Mar 8, 2026

Opens in a new windowMarriott Panama Hotel
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro Panama City Panama
Fully refundableReserve now, pay when you stay
$133 nightly
The price is $146 total per night from Mar 11 to Mar 12
$146 total
Mar 11 - Mar 12
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, express ...
8.6/10 Excellent! (1,595 reviews)
El hotel es muy lindo y bien ubicado, lo único que no me gustó es que las cortinas no son muy oscuras y entra luz en la habitación, y que la pared del baño es de vidrio y con la luz se ve que estás en el inhodoro

Reviewed on Mar 9, 2026

Opens in a new windowDecapolis Hotel Panama City
American Trade Hotel

American Trade Hotel

4.5 out of 5
Plaza Herrera Casco Viejo Panama City Panama
$234 nightly
The price is $258 total per night from Apr 5 to Apr 6
$258 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...
9.4/10 Exceptional! (674 reviews)
The hotel is located in a pleasant area and is very conveniently within walking distance of several restaurants, bars, and shops. The staff were courteous and helpful. Since it is an older building, there are a few minor inconveniences in the bathroom—for example, the lighting could be better. I ...

Reviewed on Mar 9, 2026

Opens in a new windowAmerican Trade Hotel
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
$110 nightly
The price is $121 total per night from Apr 4 to Apr 5
$121 total
Apr 4 - Apr 5
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9/10 Wonderful! (1,021 reviews)
Hotel is in a great location for partying ans shopping

Reviewed on Mar 9, 2026

Opens in a new windowCourtyard by Marriott Panama Multiplaza Mall
Studio Coliving

Studio Coliving

4.5 out of 5
Av. Ricardo Arango y, Av. Federico Boyd Panama City Panama
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Opens in a new windowStudio Coliving
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Vía Tocumen Tocumen Panama
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $138 total per night from Mar 15 to Mar 16
$138 total
Mar 15 - Mar 16
Total with taxes and fees
This smoke-free resort features a casino, 2 indoor tennis courts, and a restaurant. Bring the family and enjoy the children's pool, playground, and kid-friendly ...
8.4/10 Very Good! (1,873 reviews)
Clean room friendly staff at front desk, gift shop and restaurant. Room was lacking coffee maker and lighting was poor.

Reviewed on Mar 9, 2026

Opens in a new windowRiande Aeropuerto Hotel & Casino
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4 Star Hotels Panama Canal Zone

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Panama Canal Zone 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Panama Canal Zone will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Panama Canal Zone, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Panama Canal Zone hotel reviews by fellow wanderers