Explore top 2026 4 Star Hotels in Panama Canal Zone
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Top Panama Canal Zone 4 Star hotels
Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
Fully refundable
$133 nightly
The price is $146 total per night from May 5 to May 6
$146 total
May 5 - May 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate the children's pool, onsite laundry facilities, and babysitting. ...
8.6/10 Excellent! (2,504 reviews)
Dislikes: !. The first encounter, around 2.45 p.m., with a young lady at the checkin desk was horrible. I waited in line and when it was my turn and I was walking up to her work space, she just mumbled and directed me to go stand in the other line. No explanations on why. She remained standing at ...
Reviewed on Apr 27, 2026
Waymore Hotel Spa & Casino
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $100 total per night from May 3 to May 4
$100 total
May 3 - May 4
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free bed & breakfast. Traveling on business? Take advantage of the free ...
8.8/10 Excellent! (878 reviews)
The Staff were awesome- the place was basically clean ( hair in the bathroom on the toilet seat cover was noted upon entry)but the hotel is definitely in need of mechanical maintenance ( Hot water is almost non existent) , the shower head and arm assembly very loose in room 1723 and paint and trim ...
Reviewed on Apr 27, 2026
Radisson Hotel Panama Canal
Amador Avenue & Van Hook Street Panama City Panama
Fully refundable
$76 nightly
The price is $83 total per night from May 26 to May 27
$83 total
May 26 - May 27
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 2 outdoor pools, and a gym. Families will appreciate the children's pool and onsite laundry facilities. Unwind ...
8.6/10 Excellent! (1,009 reviews)
Excelente servicio, buena atención al cliente, el desayuno buffet estaba muy bueno. La habitación 10/10, tenía de todo. 100% recomendado. Volveríamos a ir.
Reviewed on Apr 26, 2026
Sheraton Grand Panama
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $139 total per night from May 2 to May 3
$139 total
May 2 - May 3
Total with taxes and fees
A full-service spa, 3 restaurants, and 3 outdoor tennis courts are all featured at this smoke-free resort. Families will appreciate the playground, kid-friendly ...
8.6/10 Excellent! (1,003 reviews)
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Reviewed on Apr 24, 2026
Courtyard by Marriott Panama Multiplaza Mall
Via Israel Multiplaza Pacific Mall Panama City Panama
$110 nightly
The price is $121 total per night from May 9 to May 10
$121 total
May 9 - May 10
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9/10 Wonderful! (1,009 reviews)
Breakfast was delicious. Everyone we met was ready and willing to make sure we were happy. The pool was warm and delightful. The mall is a shopper's paradise. The property is a little dated, but so are we. The temp of the water when showering was a little wonky. I also was looking forward to a bath, ...
Reviewed on Apr 27, 2026
American Trade Hotel
Plaza Herrera Casco Viejo Panama City Panama
Fully refundableReserve now, pay when you stay
$203 nightly
The price is $226 total per night from May 4 to May 5
$226 total
May 4 - May 5
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...
9.4/10 Exceptional! (714 reviews)
The vibe of this hotel is great. The rooms were well designed with nice shower and balcony. The outdoor pool wasn’t too busy and a nice place to relax. A lot of places to sit inside and outside here. The food was pretty good as well. Only downside was it’s very loud outside at the plaza with parties, ...
Reviewed on Apr 27, 2026
Ramada Plaza by Wyndham Panama Punta Pacifica
Via Israel y Calle 71, San Francisco Panama City Panama
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $107 total per night from May 5 to May 6
$107 total
May 5 - May 6
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
9.6/10 Exceptional! (1,175 reviews)
Definitely would recommend this hotel to anyone staying in Panama the hotel itself is clean with an amazing view. As well it is in walking distance to most things
Reviewed on Apr 27, 2026
Novotel Panama City
Calle Jose I. Fabrega y Thais de Pons Panama City Panama
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $119 total per night from May 28 to May 29
$119 total
May 28 - May 29
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. There's fun for all ages with a free kid's club and a playground, and families will appreciate ...
9.2/10 Wonderful! (1,170 reviews)
The room was clean price fair. Front desk, breakfast excellent. Room service extremely slow with incoherent excuses.
Reviewed on Apr 27, 2026
Studio Coliving
Av. Ricardo Arango y, Av. Federico Boyd Panama City Panama
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
7.8/10 Good! (590 reviews)
Clean, reasonable pricing. Staff was excellent, very responsive. Highly reccomend staying here
Reviewed on Mar 26, 2026
Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $157 total per night from May 2 to May 3
$157 total
May 2 - May 3
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center ...
9/10 Wonderful! (1,006 reviews)
This Hotel. is a great Hotel for whom has a need to be in the downtown location. Many restaurants and activities around it. The Hotel itself is well designed, kept in good shape. Has a nice pool and restaurant and outdoor space for a relaxing time with drinks etc. Overall a good place.
Reviewed on Apr 26, 2026
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4 Star Hotels Panama Canal Zone
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in Panama Canal Zone 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in Panama Canal Zone will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in Panama Canal Zone, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent Panama Canal Zone hotel reviews by fellow wanderers
Hyatt Regency Panama City
3 out of 5
Posted 1 hour ago
Travelocity Verified Review
"I love the cleanliness of the hotel. The staff was very helpful, knowledgeable, n was able to understand and reply to questions in english. I will not stay at this hotel next time for 2 reasons. First reason being the water was only coming at room temperature when taking a shower n the AC never came cold."
A verified traveler stayed at Hyatt Regency Panama City
