$81 Cheap flights from Des Moines Intl. to San Francisco Intl. (DSM to SFO)

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Find The Best Dates To Fly from Des Moines Intl. to San Francisco Intl.

Amazing DSM to SFO Flight Deals

The cheapest flights to San Francisco Intl. found within the past 7 days were $165 round trip and $81 one way. Prices and availability subject to change. Additional terms may apply.

Mon, May 20 - Wed, May 29
DSM
Des Moines
SFO
San Francisco
$165 Roundtrip, found 6 hours ago
$165
Roundtrip
found 6 hours ago
Select Frontier Airlines flight, departing Mon, May 20 from Des Moines to San Francisco, returning Wed, May 29, priced at $165 found 6 hours ago
Wed, Aug 21 - Sat, Aug 31
DSM
Des Moines
SFO
San Francisco
$174 Roundtrip, just found
$174
Roundtrip
just found
Select Frontier Airlines flight, departing Wed, Aug 21 from Des Moines to San Francisco, returning Sat, Aug 31, priced at $174 just found
Wed, May 22 - Wed, May 29
DSM
Des Moines
SFO
San Francisco
$179 Roundtrip, found 15 hours ago
$179
Roundtrip
found 15 hours ago
Select Frontier Airlines flight, departing Wed, May 22 from Des Moines to San Francisco, returning Wed, May 29, priced at $179 found 15 hours ago
Wed, May 29 - Tue, Jun 4
DSM
Des Moines
SFO
San Francisco
$180 Roundtrip, found 3 hours ago
$180
Roundtrip
found 3 hours ago
Select Frontier Airlines flight, departing Wed, May 29 from Des Moines to San Francisco, returning Tue, Jun 4, priced at $180 found 3 hours ago
Sat, Aug 17 - Sat, Aug 31
DSM
Des Moines
SFO
San Francisco
$187 Roundtrip, just found
$187
Roundtrip
just found
Select Frontier Airlines flight, departing Sat, Aug 17 from Des Moines to San Francisco, returning Sat, Aug 31, priced at $187 just found
Wed, Aug 14 - Wed, Aug 28
DSM
Des Moines
SFO
San Francisco
$189 Roundtrip, just found
$189
Roundtrip
just found
Select Frontier Airlines flight, departing Wed, Aug 14 from Des Moines to San Francisco, returning Wed, Aug 28, priced at $189 just found
Fri, Aug 16 - Sat, Aug 31
DSM
Des Moines
SFO
San Francisco
$191 Roundtrip, just found
$191
Roundtrip
just found
Select Frontier Airlines flight, departing Fri, Aug 16 from Des Moines to San Francisco, returning Sat, Aug 31, priced at $191 just found
Sat, Aug 10 - Wed, Aug 28
DSM
Des Moines
SFO
San Francisco
$192 Roundtrip, just found
$192
Roundtrip
just found
Select Frontier Airlines flight, departing Sat, Aug 10 from Des Moines to San Francisco, returning Wed, Aug 28, priced at $192 just found
Wed, May 15 - Wed, May 22
DSM
Des Moines
SFO
San Francisco
$194 Roundtrip, found 3 days ago
$194
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Wed, May 15 from Des Moines to San Francisco, returning Wed, May 22, priced at $194 found 3 days ago
Sat, Aug 17 - Wed, Sep 4
DSM
Des Moines
SFO
San Francisco
$200 Roundtrip, just found
$200
Roundtrip
just found
Select Frontier Airlines flight, departing Sat, Aug 17 from Des Moines to San Francisco, returning Wed, Sep 4, priced at $200 just found

Best San Francisco Intl. Flight and Hotel Packages

San Francisco Intl. flight + hotel packages - economy flights

Price found within the past 48 hours. Click for updated prices.
Graduate Palo Alto

Graduate Palo Alto

4 out of 5
Save 100% on your flight
per person
Jun 15 - Jun 19
Roundtrip non-stop flight included
Des Moines (DSM) to San Francisco (SFO)
Locale Menlo Park

Locale Menlo Park

4 out of 5
per person
Jun 15 - Jun 19
Roundtrip non-stop flight included
Des Moines (DSM) to San Francisco (SFO)
Larkspur Landing Sunnyvale - An All-Suite Hotel

Larkspur Landing Sunnyvale - An All-Suite Hotel

3 out of 5
per person
Jun 15 - Jun 19
Roundtrip non-stop flight included
Des Moines (DSM) to San Francisco (SFO)
Crowne Plaza Cabana, Palo Alto, an IHG Hotel

Crowne Plaza Cabana, Palo Alto, an IHG Hotel

3.5 out of 5
per person
Jun 15 - Jun 19
Roundtrip non-stop flight included
Des Moines (DSM) to San Francisco (SFO)
The Palo Alto Inn

The Palo Alto Inn

3 out of 5
per person
Jun 15 - Jun 19
Roundtrip non-stop flight included
Des Moines (DSM) to San Francisco (SFO)
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Frequently asked questions

Can I catch a flight from Des Moines Intl. Airport to San Francisco Airport right now?
Ensure you visit the Covid-19 Travel Advisor to see if there are any present quarantine requirements and travel advice reports in effect in SFO when flying in from Des Moines Intl. Airport (DSM).
Are there direct flights from Des Moines Intl. Airport (DSM) to SFO?
You’ll need to be prepared for a stopover when jetting from Des Moines Intl. Airport to SFO. No direct flights are on offer on this route, however United Airlines, American Airlines and Delta will get you to your destination as swiftly as possible.
If I am not able to travel due to COVID-19, can I change my booking to a later date?
For more info about changing your flight to San Francisco Intl. Airport (SFO), please visit our Customer Service Portal.
How long is the flight from Des Moines Intl. Airport (DSM) to SFO?
It usually takes around 5 hours and 42 minutes to travel from DSM to SFO. You’ll be cruising at altitude for a while, so amuse yourself with a film or flick through the in-flight magazine.
What is the flight distance from Des Moines Intl. Airport (DSM) to San Francisco Intl. Airport (SFO)?
Covering 1,550 mi between Des Moines Intl. Airport (DSM) and Des Moines Intl. Airport (DSM) calls for a glass of Champagne and a good movie. Put your seat back, relax and just enjoy the ride.
What airlines fly from Des Moines Intl. Airport to San Francisco Airport?
You’ll have to make at least one stopover if you’re traveling from DSM to San Francisco Airport, as no airlines operate direct flights between these destinations. Make the most of your layover time by giving your legs a stretch, freshening up and checking out what the stores have on offer.
What airlines have practices regarding COVID-19 in place and use social distancing?
From the moment you enter the departure terminal to when you leave the arrivals terminal, if you’re flying with United Airlines, Alaska Airlines or Delta you can be sure that COVID-19 measures and social distancing rules have been adhered to. Many airlines have introduced capped capacity flights and keeping the middle seat empty.
What is the best day to buy a plane ticket?
This just in! Airfares offered on Thursdays tend to be the cheapest, according to flight demand on Travelocity in 2021. Tuesday and Wednesday prices are also good, but you may want to prepare your budget if booking during the weekend, as data shows that is when prices are generally at their highest.
What are the cheapest days to fly?
Frequent travelers may already know this, but earlier in the week can be the cheapest time to fly. In 2021, flights departing on a Monday were generally the cheapest of the week, whereas you may pay a premium for weekend flights when demand is usually high. On average, tickets were most expensive for Saturday departures, so if you need to fly out on a weekend, you might look for deals ahead of time.
How far in advance can you book a flight?
Trying to figure out how early you should book your flight? It’s possible to start comparing international airfares on Travelocity up to 12 months in advance. However, it does depend on the carrier as not all airlines release their prices that far out. According to our 2021 flight demand trends, last minute planners can still bag a bargain with some of the cheapest fares appearing 0-2 weeks prior to their travel dates.*According to flight demand on Travelocity.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

 

Traveling From
Des Moines Intl.
Traveling To
San Francisco Intl.
Shortest Flight Time
 hours mins
Earliest Departure Time
Latest Departure Time
Lowest Flight Price
$165

Route Info

Flight path for flights from Des Moines International Airport to San Francisco International Airport.


Origin:
DSM - Des Moines International Airport
Destination:
SFO - San Francisco International Airport
Distance:
2,000.00 miles


Discover our best flights from Des Moines DSM to San Francisco SFO. 

With 20 airlines to choose from on Travelocity, you can easily find the best option for you. Use our filters to sort by price, compare airlines, and find the most convenient flight times. 

 

Find our best return flights from Des Moines DSM to San Francisco SFO at the right price  

Airfares to San Francisco SFO from Des Moines DSM currently cost between $165 and $200. It’s usually cheaper to book a round trip than two separate one-way flights. Prices and availability subject to change. Additional terms may apply. 

 

Book one-way flights from Des Moines DSM to San Francisco SFO 

If you want to be flexible about when you return, or keep your travel options open ended, a one-way flight could be just the ticket! You’ll find one-way airfares from Des Moines DSM to San Francisco SFO on Travelocity starting at $81. Prices and availability subject to change. Additional terms may apply. 

 

Get to San Francisco SFO from Des Moines DSM quicker with direct flights. 

Get to San Francisco faster, without the hassle of changing planes and moving baggage, by booking a direct flight. Expect your direct flight to SFO from DSM to take around hour(s) min(s).  

 

Find our cheapest airfares for flights from Des Moines DSM to San Francisco SFO

Find cheap flight deals by using our search filters to sort results starting with the lowest price airfares to SFO from DSM. Our Price Match Promise means if you find a lower rate on Travelocity.com or on another US-based website within 24 hours of booking, we’ll credit or refund the difference.  

 

Get our best airfare deals for your flight from Des Moines DSM to San Francisco SFO today 

If you’re flexible about when you travel, May is usually the cheapest month to fly from Des Moines DSM to San Francisco SFO. If you need to be more specific, search by date and arrival and departure times.Then, compare prices across different airlines, and sort results by lowest price first. 

 

Book flexible airline tickets for flights to San Francisco SFO from Des Moines DSM 

Some airlines let you change your travel dates without charging a fee. Use our ‘no change fee’ filter to see which flights to SFO from DSM have this option.  

 

Travel with confidence when you book flights to San Francisco SFO from Des Moines DSM with Travelocity 

We’ve secured fantastic deals with all the main airline carriers and it’s easy to compare, choose, and book with Travelocity. With 24/7 customer service and our free 'App', we’ll always keep you moving. 

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.