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Top Santa Clara hotels

Hyatt Regency Panama City

Hyatt Regency Panama City

5 out of 5
Calle 52 and Ricardo Arias Panama City
Fully refundableReserve now, pay when you stay
$164 nightly
The price is $180 total per night from May 31 to Jun 1
$180 total
May 31 - Jun 1
Total with taxes and fees
This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...
Unfortunately the restaurant menu was very limited and breakfast was expensive. Few options for dinner limited. If you are a tourist I would recommend staying in the Old Town District

Reviewed on Apr 28, 2026

Opens in a new windowHyatt Regency Panama City
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla Panama City Panama
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $114 total per night from May 9 to May 10
$114 total
May 9 - May 10
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Good

Reviewed on Apr 28, 2026

Opens in a new windowPlaza Paitilla Inn Hotel
The Executive Hotel

The Executive Hotel

3.5 out of 5
Calle 52 Panama City Panama
Fully refundable
$81 nightly
The price is $89 total per night from May 6 to May 7
$89 total
May 6 - May 7
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Good location, nice room upgrade with space. Clean surrounding and breakfast was ok,

Reviewed on Apr 29, 2026

Opens in a new windowThe Executive Hotel
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
$121 nightly
The price is $133 total per night from May 9 to May 10
$133 total
May 9 - May 10
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
The breakfast was great, the room was clean with a lovely view, staff were friendly.

Reviewed on Apr 29, 2026

Opens in a new windowHotel Riu Plaza Panama
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina Panama City Panama
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $62 total per night from May 3 to May 4
$62 total
May 3 - May 4
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Room was ok, staff very polite and helpful. Felt safe at all timed

Reviewed on Apr 29, 2026

Opens in a new windowPrincipe Hotel and Suites
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $99 total per night from May 6 to May 7
$99 total
May 6 - May 7
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free bed & breakfast. Traveling on business? Take advantage of the free ...
I really enjoyed the breakfast with a variety of different foods and fruits. The eggplant and omelet was my favorite

Reviewed on Apr 29, 2026

Opens in a new windowWaymore Hotel Spa & Casino
Radisson Hotel Panama Canal

Radisson Hotel Panama Canal

4.5 out of 5
Amador Avenue & Van Hook Street Panama City Panama
Fully refundable
$74 nightly
The price is $81 total per night from May 14 to May 15
$81 total
May 14 - May 15
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 2 outdoor pools, and a gym. Families will appreciate the children's pool and onsite laundry facilities. Unwind ...
Excelente servicio, buena atención al cliente, el desayuno buffet estaba muy bueno. La habitación 10/10, tenía de todo. 100% recomendado. Volveríamos a ir.

Reviewed on Apr 26, 2026

Opens in a new windowRadisson Hotel Panama Canal
Hotel Ojos del Rio

Hotel Ojos del Rio

3.5 out of 5
calle 41 este Panama City Panama
Fully refundableReserve now, pay when you stay
$46 nightly
The price is $51 total per night from May 8 to May 9
$51 total
May 8 - May 9
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. WiFi in public areas is free. A business center, a coffee shop, and a terrace are also on offer.
Hotel is ok for a couple nights

Reviewed on Apr 29, 2026

Opens in a new windowHotel Ojos del Rio
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz Veracruz Panama
Fully refundableReserve now, pay when you stay
$307 nightly
The price is $307 total per night from May 21 to May 22
$307 total
May 21 - May 22
Total with taxes and fees
This all-inclusive property features a full-service spa, a nightclub, and 7 restaurants. Spend a day at the beach kayaking, or relax with free beach cabanas ...
Clean room. Very friendly staff.

Reviewed on Apr 29, 2026

Opens in a new windowDreams Playa Bonita Panama - All Inclusive
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Santa Clara?
Take some of the trials out of traveling with kids by booking a family-friendly Santa Clara hotel. From thoughtful amenities to more services, these stays come with perks that'll help make your getaway run like a dream: Jungle Land Panama Lodge will help make your getaway the best one yet. It offers a host of conveniences geared toward families, such as complimentary breakfast and a picnic area. Otherwise, spend your nights in Santa Clara at Casa en Gamboa al lado Canal de Panama. Make the most of a nearby beach, a beach shuttle and more here.
Where can I find cheap hotels in Santa Clara?
At Travelocity you'll find really nice hotels in Santa Clara at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Santa Clara rather than in Santa Clara. We may find you even better rates, too.
How do I find the best Santa Clara hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Santa Clara then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Santa Clara?
The cheapest hotel in Santa Clara is $51. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Santa Clara?
There are 1,576 hotels in Santa Clara on Travelocity.
What are the best hotels in Santa Clara?
Santa Clara has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Santa Clara for you!
When is the best time to visit Santa Clara?
If you want the joy of a fun-filled trip in peak season, visit Santa Clara during February, March and April. If you'd prefer the peace of off-season, book a stay during quieter months, such as September, October and December.
When is the cheapest time to stay in Santa Clara?
Based on historic data is usually the cheapest month to visit Santa Clara. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Santa Clara?
There are multiple hotels in Santa Clara that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Santa Clara. We have plenty of kid-friendly hotels in Santa Clara to choose from on Travelocity!
Why book a hotel in Santa Clara through Travelocity?
Because we have the top hotels in Santa Clara! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Santa Clara on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Santa Clara hotel reviews by fellow wanderers

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Posted 10 hours ago
Travelocity Verified Review
"The breakfast was great, the room was clean with a lovely view, staff were friendly."
A verified traveler stayed at Hotel Riu Plaza Panama
Hotel Riu Plaza Panama

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