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Top Santa Clara hotels

The Executive Hotel
Calle 52 Panama City Panama
Fully refundable
$90 nightly
The price is $98 total per night from Jul 17 to Jul 18
$98 total
Jul 17 - Jul 18
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
"Excellent staff and great communication! Outstanding kitchen, staff and restaurant staff, despite not knowing English and us not knowing Spanish as well. Working together to communicate worked out nicely. The staff created a very nice welcome in environment throughout the stay. One thing I think ..."
Reviewed on Jun 18, 2026

Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $162 total per night from Jun 29 to Jun 30
$162 total
Jun 29 - Jun 30
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
"Everything was OK, just no sleeper and tooth brush in the room. We request late checout was not accepted."
Reviewed on Jun 18, 2026

Principe Hotel and Suites
Via Argentina Panama City Panama
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $62 total per night from Jun 20 to Jun 21
$62 total
Jun 20 - Jun 21
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
"Loved the location"
Reviewed on Jun 18, 2026

Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
Fully refundableReserve now, pay when you stay
$141 nightly
The price is $155 total per night from Jul 16 to Jul 17
$155 total
Jul 16 - Jul 17
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center ...
"Very confusing having the reception not on the main entrance"
Reviewed on Jun 16, 2026

MARINN PLACE Financial District
C. Aquilino de la Guardia Panama City Panamá Province
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $93 total per night from Jun 20 to Jun 21
$93 total
Jun 20 - Jun 21
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Desde que tienen nuevo lobby, se les subieron los humos. El hotel esta muy lindo, las habitaciones excelentes, sin embargo el personal no es muy amable, pese a que tienen un pin que dice que atienden con el corazon. El desayuno es un caos."
Reviewed on Jun 17, 2026

Waymore Hotel Spa & Casino
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $127 total per night from Jun 19 to Jun 20
$127 total
Jun 19 - Jun 20
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free bed & breakfast. Traveling on business? Take advantage of the free ...
"DO NOT STAY AT THE WAYMORE HOTEL! I was a solo female traveler who booked via Expedia to stay 15 nights in March 2026. However after arriving I immediately felt unsafe. In the area there were prostitutes outside the hotel at night. The casino in the hotel attracted drunk undesirable men who were ..."
Reviewed on Jun 16, 2026

Sheraton Grand Panama
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $145 total per night from Jul 4 to Jul 5
$145 total
Jul 4 - Jul 5
Total with taxes and fees
A full-service spa, 3 restaurants, and 3 outdoor tennis courts are all featured at this smoke-free resort. Families will appreciate the playground, kid-friendly ...
"Not good enough"
Reviewed on Jun 18, 2026

Dreams Playa Bonita Panama - All Inclusive
KM 7, Road to Veracruz Veracruz Panama
Fully refundableReserve now, pay when you stay
$299 nightly
The price is $299 total per night from Jun 19 to Jun 20
$299 total
Jun 19 - Jun 20
Total with taxes and fees
This all-inclusive property features a full-service spa, a nightclub, and 7 restaurants. Spend a day at the beach kayaking, or relax with free beach cabanas ...
"Everyone was very friendly and courteous. Property was clean and the entire trip was just excellent. Love Panama and absolutely love the staff at Dreams Playa Bonita. Felt like home."
Reviewed on Jun 16, 2026

Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals
Avenida Peru Y Calle 30 Panama City Panama Province
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $75 total per night from Jun 22 to Jun 23
$75 total
Jun 22 - Jun 23
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Guests will appreciate free perks like buffet breakfast and WiFi in public areas. An area ...
"Tenía una mejor expectativa del Soloy pero fue la peor experiencia en Panamá. El Aire Acondicionado no funcionó y el de mantenimiento solo dijo que el aire no daba para más y con los calores de Panamá no se podía dormir, la habitación no la limpiaban, dejaban todo igual diario. Me queje en recepción ..."
Reviewed on Jun 16, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Santa Clara hotel reviews by fellow wanderers

Hotel Riu Plaza Panama
4 out of 5
Posted 5 hours ago
Travelocity Verified Review
"Everything was OK, just no sleeper and tooth brush in the room. We request late checout was not accepted."
A verified traveler stayed at Hotel Riu Plaza Panama
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