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Top hotels in Santa Clara

The Executive Hotel

The Executive Hotel

3.5 out of 5
Calle 52 Panama City Panama
Fully refundable
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
J’ai bien aimé cette hôtel bon rapport qualité prix! Le personnel était vraiment sympathique.

Reviewed on Mar 17, 2026

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Opens in a new windowThe Executive Hotel
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
$157 nightly
The price is $172 total per night from Mar 30 to Mar 31
$172 total
Mar 30 - Mar 31
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Hotel is perfectly situated in the middle of the city, the hotel dos need some improvement as does look tired. Staff is amazing and the amenities are great. Breakfast is fantastic and service by the pool is also great.

Reviewed on Mar 17, 2026

Opens in a new windowHotel Riu Plaza Panama
W Panama

W Panama

5 out of 5
Calle Aquilino de la Guardia & Calle 50 Panama City
$199 nightly
The price is $219 total per night from Mar 31 to Apr 1
$219 total
Mar 31 - Apr 1
Total with taxes and fees
This luxury hotel features 2 restaurants, 3 hot tubs, and an outdoor pool. Make the most of the gym and a rooftop terrace, and relax with drinks at one of the ...
Beautiful property in a great location! Received a free upgrade at check in and really enjoyed the room.

Reviewed on Mar 18, 2026

Opens in a new windowW Panama
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina Panama City Panama
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $62 total per night from Mar 22 to Mar 23
$62 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Hotel in a very convenient location. On this occasion as the Queen rooms were not available we booked a junior suite which we thought would be one of the rooms with a kitchenette area however it was a rather strange room with a lounge area and a bath in the bathroom. There was supposed to be a coffee ...

Reviewed on Mar 17, 2026

Opens in a new windowPrincipe Hotel and Suites
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street Panama City Panama
Fully refundableReserve now, pay when you stay
$270 nightly
The price is $297 total per night from Mar 30 to Mar 31
$297 total
Mar 30 - Mar 31
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, kid-friendly ...
Excellent hotel, staff, and re

Reviewed on Mar 12, 2026

Opens in a new windowWaldorf Astoria Panama
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $121 total per night from Mar 27 to Mar 28
$121 total
Mar 27 - Mar 28
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free bed & breakfast. Traveling on business? Take advantage of the free ...
The room and the breakfast are excelent, the staff is also really great.

Reviewed on Mar 16, 2026

Opens in a new windowWaymore Hotel Spa & Casino
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Fully refundable
$139 nightly
The price is $153 total per night from Mar 23 to Mar 24
$153 total
Mar 23 - Mar 24
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate the children's pool, onsite laundry facilities, and babysitting. ...
Room was OK. Close to airport which is convenient for a quick stay. TV was old and screen barely worked. Bartender tried to charge us almost $100 USD for 2 drinks. After I questioned they changed it to $20 so be sure to check your bill!

Reviewed on Mar 17, 2026

Opens in a new windowCrowne Plaza Panama Airport by IHG
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $148 total per night from Apr 3 to Apr 4
$148 total
Apr 3 - Apr 4
Total with taxes and fees
A full-service spa, 3 restaurants, and 3 outdoor tennis courts are all featured at this smoke-free resort. Families will appreciate the playground, kid-friendly ...
El personal de servicio excelente muy amables y te ayudaban a encontrar lugares para visitar

Reviewed on Mar 16, 2026

Opens in a new windowSheraton Grand Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $113 total per night from Mar 23 to Mar 24
$113 total
Mar 23 - Mar 24
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 3 restaurants. Families will appreciate the children's pool, onsite laundry facilities, and ...
Staff was great but the hotel needs an upgrade.

Reviewed on Mar 18, 2026

Opens in a new windowHotel El Panama by Faranda Grand, a member of Radisson Individuals
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santa Clara Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Santa Clara area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Santa Clara to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Santa Clara are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Santa Clara hotel reviews by fellow wanderers

W Panama

W Panama

5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Beautiful property in a great location! Received a free upgrade at check in and really enjoyed the room."
A verified traveler stayed at W Panama
W Panama

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