
Deals on vacations and trips to San Francisco

San Francisco flight + hotel vacation packages
Price found within the past 48 hours. Click for updated prices.

Playa Caracol Residences Vacation Rental
Price was $1,060, price is now $700 per person
$700
per person
Jan 28 - Feb 2
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
This smoke-free apartment features 2 outdoor pools, a restaurant, and a bar/lounge. Relax with a drink at the poolside bar and enjoy perks like free self parking. A coffee shop and a snack bar/deli are also provided.

Central Hotel Panama Casco Viejo
Casco Viejo
Save 100% on your flight
Price was $1,269, price is now $815 per person
$815
per person
Feb 26 - Mar 1
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this Belle Époque hotel. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. Enjoy the 24-hour gym and unwind at the bar/lounge and poolside bar.

Villa Marina Lodge & Condos
Price was $1,010, price is now $720 per person
$720
per person
Feb 5 - Feb 9
found 24 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
This inn features a restaurant, an outdoor pool, and a bar/lounge. Relax with a drink at the poolside bar and enjoy perks like free self parking and free WiFi. A terrace, a garden, and a snack bar/deli are also on offer.

Megapolis Hotel Panamá
San Francisco
Price was $1,372, price is now $1,004 per person
$1,004
per person
Jan 14 - Jan 18
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 3 bars/lounges and enjoy free perks like buffet breakfast and free self parking.

Casa Mallet by Wynwood House
Casco Viejo
Price was $1,745, price is now $1,301 per person
$1,301
per person
Feb 28 - Mar 5
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Free WiFi in public areas is available at this apartment. Take advantage of the self parking.
Top San Francisco hotels deals

Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
Free Cancellation
Reserve now, pay when you stay
$157 nightly
The price is $175 total per night
$175 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. You'll appreciate the gym, bar/lounge, and coffee shop.
Pool
Spa

Megapolis Hotel Panamá
Avenida Balboa Panama City
Free Cancellation
Reserve now, pay when you stay
$131 nightly
The price is $144 total per night
$144 total
Dec 15 - Dec 16
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 3 bars/lounges and enjoy free perks like buffet breakfast and free self parking.
Pool
Hot Tub

Plaza Paitilla Inn Hotel
Italy Avenue, Punta Paitilla Panama City Panama
Free Cancellation
Reserve now, pay when you stay
$108 nightly
The price is $119 total per night
$119 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Enjoy the gym and free perks like buffet breakfast and free self parking.
Pool
Breakfast included

Sheraton Grand Panama
Via Israel And 77th Street Panama City Panama
Free Cancellation
Reserve now, pay when you stay
$134 nightly
The price is $148 total per night
$148 total
Jan 9 - Jan 10, 2026
Total with taxes and fees
A full-service spa, 3 restaurants, and 3 outdoor tennis courts are all featured at this smoke-free resort. Families will appreciate the playground, kid-friendly dining, and in-room childcare. Relax with a drink at one of the 2 bars/lounges and enjoy free perks like free self parking and WiFi in public areas.
Pool
Spa

Decapolis Hotel Panama City
Avenida Balboa Con Multicentro Panama City Panama
Free Cancellation
Reserve now, pay when you stay
$113 nightly
The price is $125 total per night
$125 total
Jan 12 - Jan 13, 2026
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, and free valet parking. Enjoy the outdoor pool and free buffet breakfast each morning.
Pool
Breakfast included

JW Marriott Panama
Calle Punta Colon, Punta Pacifica Panama City Panama
Free Cancellation
Reserve now, pay when you stay
$260 nightly
The price is $286 total per night
$286 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This luxury hotel features 3 restaurants, 4 outdoor pools, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, and valet parking. There's a poolside bar on site, and concierge services and wedding services are also provided.
Pool
Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit

Multiplaza Pacific Mall
4.5/5(634 reviews)
During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
ATLAPA Conventions Center
3.5/5(21 reviews)
Learn about the events happening at ATLAPA Conventions Center during your trip to Panama City. Stroll along the seaside in this vibrant area, or check out its lively bars.
Multicentro Panama
4/5(148 reviews)
During your trip to Panama City, you can find the perfect gifts to bring home at Multicentro Panama. Stroll along the seaside or visit the casinos in this vibrant area.
Frequently asked questions
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