Deals on vacations and trips to San Francisco

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San Francisco flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.
Villa Marina Hotel

Villa Marina Hotel

3.5 out of 5
Price was $1,225, price is now $867 per person
$867
per person
Nov 7 - Nov 11
found 1 day ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
This hotel features 2 bars/lounges, a beach bar, and a restaurant. Families will appreciate the onsite laundry facilities, kid-friendly dining, and in-room childcare. Enjoy the outdoor pool and perks like free self parking and free WiFi.
Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House

3.5 out of 5
Casco Viejo
Save 100% on your flight
Price was $2,185, price is now $1,499 per person
$1,499
per person
Oct 31 - Nov 7
found 8 hours ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
This apartment features a virtual front desk.
Yoo by Wynwood House

Yoo by Wynwood House

4 out of 5
Calidonia
Price was $1,744, price is now $1,250 per person
$1,250
per person
Oct 31 - Nov 7
found 8 hours ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
This condo features an outdoor pool and a gym. Staff at the 24-hour front desk can provide around-the-clock assistance.
Casa La Costa By Wynwood House

Casa La Costa By Wynwood House

3.5 out of 5
Casco Viejo
Price was $1,619, price is now $1,179 per person
$1,179
per person
Oct 31 - Nov 7
found 8 hours ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
This apartment features a virtual front desk.
Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

4 out of 5
Casco Viejo
Price was $1,663, price is now $1,232 per person
$1,232
per person
Nov 22 - Nov 27
found 2 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Free WiFi in public areas is available at this apartment. Take advantage of the self parking.

Top San Francisco hotels deals

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
Free Cancellation
Reserve now, pay when you stay
$143 nightly
The price is $157 total per night
$157 total
Sep 20 - Sep 21
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 3 bars/lounges and enjoy free perks like buffet breakfast and free self parking.
Pool
Hot Tub
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

4 out of 5
Via Israel y Calle 71, San Francisco Panama City Panama
$93 nightly
The price is $102 total per night
$102 total
Oct 3 - Oct 4
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Relax with a drink at the bar/lounge and enjoy the free buffet breakfast each morning.
Pool
Breakfast included
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro Panama City Panama
Free Cancellation
Reserve now, pay when you stay
$101 nightly
The price is $111 total per night
$111 total
Sep 28 - Sep 29
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, and free valet parking. Enjoy the outdoor pool and free buffet breakfast each morning.
Pool
Breakfast included
Aloft by Marriott Panama

Aloft by Marriott Panama

3.5 out of 5
Via Israel & Calle 76 Panama City Panama
Free Cancellation
Reserve now, pay when you stay
$132 nightly
The price is $146 total per night
$146 total
Sep 25 - Sep 26
Total with taxes and fees
A nightclub, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the outdoor pool and perks like free self parking.
Pool
Pet friendly
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
Free Cancellation
Reserve now, pay when you stay
$110 nightly
The price is $121 total per night
$121 total
Sep 26 - Sep 27
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the gym and perks like free self parking.
Pool
Pet friendly
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
Free Cancellation
Reserve now, pay when you stay
$151 nightly
The price is $166 total per night
$166 total
Sep 19 - Sep 20
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and perks like free self parking.
Pool
Spa
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular San Francisco attractions

Multiplaza Pacific Mall

9.0/10 (4,497 reviews)
During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
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Frequently asked questions

How much are vacation packages to San Francisco?
$867 is all you need to spend for an unforgettable escape in San Francisco. Bundle your hotel and flights into a Travelocity package and watch all the savings pile up. With these kinds of prices, there's never been a better time to travel.
Where can I get the best vacation package deals for San Francisco?
It's hard to look past Travelocity when it comes to piecing together your San Francisco package deal. There are as many as 400 partner airlines and 1,000,000 worldwide properties to choose from. Reserve your trip now and get ready to cross another amazing place off your must-visit list.
Why should I book my San Francisco vacation bundle via Travelocity?
From our 24/7 customer care to our range of incredible destinations, we're dedicated to fulfilling your travel desires. All you need to do is click and book — our Price Match Guarantee will ensure you lock in the best deal.
Can I save on my San Francisco car rental if I combine it with a hotel or flight?
Sure can — and booking one of our San Francisco vacation packages is the best way to go about this. Bundle any combination of a car, hotel, flight and experience and score serious discounts. The more you book, the more you'll save. There are so many famous sights in San Francisco to put on your bucket list, including Gatun Locks (35 mi from San Francisco). Nothing tops exploring places like this with the freedom of your own wheels.
What is there to do in San Francisco?
Multicentro Panama and Panama Canal Murals are loved by tourists and locals alike. Tick these places off your San Francisco itinerary and see what the hype is about.

Photos of local treasures

Browse San Francisco vacation photos for more inspiration

A bridge over a body of water with several boats.
A beach with a large driftwood piece, calm water, and a few people in the distance.
A city skyline with a flag, a river, and a park.
A cityscape with a distinctive twisted skyscraper, a busy highway, and surrounding modern buildings.
A cityscape with a rainbow over buildings.