Book Hotels in Mission Hill, SD
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Top Mission Hill hotels

Fairfield Inn & Suites by Marriott Yankton
508 WEST 21ST STREET Yankton SD
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $121 total per night from Jan 25 to Jan 26
$121 total
Jan 25 - Jan 26
Total with taxes and fees
An indoor pool is featured at this hotel, along with free self parking. Guests will appreciate free perks like continental breakfast and WiFi in public areas. ...
The room was immaculate!! Beautiful facility and probably the best hotel in Yankton. Very happy!
Reviewed on Jan 2, 2026

Holiday Inn Express & Suites Yankton by IHG
2607 Broadway Ave Yankton SD
Fully refundable
$106 nightly
The price is $117 total per night from Jan 26 to Jan 27
$117 total
Jan 26 - Jan 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Nice rooms and a wonderful choice of breakfast items!
Reviewed on Jan 15, 2026

Comfort Inn Yankton SD
611 W 23rd Street Yankton SD
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $98 total per night from Jan 25 to Jan 26
$98 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies ...
Our room was clean and comfortable. We enjoyed relaxing in the whirlpool.
Reviewed on Jan 12, 2026

Best Western Vermillion Inn
701 W Cherry St Vermillion SD
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $106 total per night from Feb 1 to Feb 2
$106 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. There's a sauna on site, and a 24-hour ...
Yes
Reviewed on Jan 2, 2026

Holiday Inn Express Hotel & Suites Vermillion by IHG
1200 N Dakota St Vermillion SD
$113 nightly
The price is $125 total per night from Jan 22 to Jan 23
$125 total
Jan 22 - Jan 23
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Guests will appreciate free perks like free self parking and WiFi in public areas. A 24-hour business center, ...
Booked for the stay, and nothing was mentioned about the hotel being remodeled beforehand.
Reviewed on Jan 5, 2026

Best Western Kelly Inn
1607 E Highway 50 Yankton SD
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $104 total per night from Jan 25 to Jan 26
$104 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Great pool. Kids loved it.
Reviewed on Jan 13, 2026

Red Roof Inn Vermillion - U of South Dakota
1208 E Cherry St Vermillion SD
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $88 total per night from Jan 20 to Jan 21
$88 total
Jan 20 - Jan 21
Total with taxes and fees
An indoor pool is featured at this hotel, along with free self parking. WiFi in public areas is free. A snack bar/deli is provided and the front desk is staffed ...
Nice room. Great breakfast
Reviewed on Jan 10, 2026

Yankton Inn
1603 East Highway 50 Yankton SD
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $92 total per night from Jan 21 to Jan 22
$92 total
Jan 21 - Jan 22
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide ...
Clean room, low pet fee, quiet.
Reviewed on Dec 4, 2025

Prairie Inn
916 N Dakota Street Vermillion SD
$77 nightly
The price is $84 total per night from Jan 22 to Jan 23
$84 total
Jan 22 - Jan 23
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Guests will appreciate free perks like free self parking and WiFi in public areas. The front desk is ...
Rooms are dated, but clean, quiet and great for the price.
Reviewed on Jan 9, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Mission Hill hotel reviews by fellow wanderers

Holiday Inn Express & Suites Yankton by IHG
5 out of 5
Posted 4 days ago
Travelocity Verified Review
"Nice rooms and a wonderful choice of breakfast items!"
A verified traveler stayed at Holiday Inn Express & Suites Yankton by IHG






