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Top Los Osos hotels

Back Bay Inn
Wine reception, views, and location.
Reviewed on Nov 9, 2025

Quality Suites Downtown San Luis Obispo
One of the best stays I've ever had. Amazing staff when I walked in, clean rooms and AMAZING breakfast. I would stay here again forsure.
Reviewed on Nov 25, 2025

Madonna Inn
Madonna Inn was a spectacular getaway. We were pleased with our view from the Matterhorn room and the comfortable bed and spacious room. Delicious food options on the property and friendly staff. We can’t wait to return!!
Reviewed on Nov 27, 2025

SeaCrest OceanFront Hotel
Breakfast menu was decent. Typical menu consisting of cereal, pancakes, waffles, scrambled eggs, and sausage. Some of the food was not as good, but the rest was okay.
Reviewed on Nov 21, 2025

Cottage Inn By The Sea
Love this place
Reviewed on Nov 27, 2025

Spyglass Inn
Loved when you walk in the room is super clean. Love that I had acces to fire pit outside and enjoyed it. Reception very friendly gave me a list of restaurants to enjoy. My stay was wonderful.
Reviewed on Nov 26, 2025

Sandcastle Hotel on the Beach
The stay was amazing, room was upgraded free of charge to a full beach front view. The staff was friendly and very accommodating.
Reviewed on Nov 22, 2025

La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown
Room was clean and spacious. Staff was very nice. Great location and parking was convenient.
Reviewed on Nov 26, 2025

Edgewater Inn And Suites
Rooms are close to the beach. Perfect for taking the dog down for a stroll amd bathroom break. Rooms do have very thin walls so if you're in need of absolute quiet, I would not recommend.
Reviewed on Nov 26, 2025
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Los Osos Hotel & Travel Guide\n
If you're not sure how to begin planning your San Luis Obispo trip, rest assured, because there's no end of perfect accommodation options in Los Osos. Thanks to our handy accommodation guide, you can explore 30 rooms within 6 miles (10 kilometers) of Los Osos's downtown region.
The Sea Pines is a great option for your stay because it is one of the most ideally located options, one of only a small number of choices that are within walking distance of the Los Osos central area.
The Dolphin Bay Resort And Spa is approximately 12 miles (19 kilometers) outside of the center of Los Osos. Another alternative is the Avila La Fonda Hotel, which is situated 9 miles (15 kilometers) away. Other possible hotel options are the Avila Lighthouse Suites and the San Luis Bay Inn.
Should you have the time, you could travel to other parts of the Central California region. Photograph the scenery of Central California's valleys and rolling hills. You could also wind your way through many of the area's lighthouses. In this corner of United States of America adventurous visitors might also try their hand at snowboarding, skiing and mountain biking.
14 miles (22 kilometers) away from Los Osos, you'll reach Pismo Beach, where you can spend the day visiting Pismo Beach Pier and Monarch Butterfly Grove. If you'd like to spend a few nights in Pismo Beach, check out the Sandcastle Inn and Pismo Lighthouse Suites. 9 miles (15 kilometers) to the southeast of Los Osos, is Avila Beach, which is home to the Avila Village Inn and Inn At Avila Beach. If you visit Avila Beach, keep a day to explore the Avila Beach Golf Resort and Central Coast Aquarium.
Get yourself a serving of local sport with a journey to Alex G. Spanos Stadium, which is 9 miles (15 kilometers) to the east of Los Osos. Wise travelers that want to book Travelocity-listed accommodation nearby can choose from the Madonna Inn or the Granada Hotel & Bistro.
San Luis Obispo County Regional Airport is located 11 miles (18 kilometers) outside Los Osos's town center. Modern visitors who desire to find accommodation in the area can find a night at the Courtyard by Marriott San Luis Obispo or Embassy Suites by Hilton San Luis Obispo.
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Madonna Inn
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