Explore 10 Luxury Hotels in Little Italy

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Best Luxury Hotels in Little Italy

Urban Boutique Hotel

Urban Boutique Hotel

1654 Columbia Street, San Diego, CA
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $144 total per night from Nov 19 to Nov 20
$144 total
Nov 19 - Nov 20
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the 24-hour business ...
8.6/10 Excellent! (1,265 reviews)
"We really enjoyed our stay here. Staff were helpful and kind. The location was absolutely perfect."

Reviewed on Oct 14, 2025

Opens in a new windowUrban Boutique Hotel
La Pensione Hotel

La Pensione Hotel

606 West Date Street, San Diego, CA
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $169 total per night from Nov 3 to Nov 4
$169 total
Nov 3 - Nov 4
Total with taxes and fees
A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. A coffee ...
8.6/10 Excellent! (1,887 reviews)
"The staff was very friendly and the atmosphere when you walk in is very pretty. The rooms are small, but I didn’t mind. I did think the room cleanliness could be higher since there was dust in the corners of the room… but the bed and bathroom were very clean. The location is prime and walking distance ..."

Reviewed on Oct 13, 2025

Opens in a new windowLa Pensione Hotel
Hampton Inn San Diego-Downtown

Hampton Inn San Diego-Downtown

San Diego
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $161 total per night from Nov 10 to Nov 11
$161 total
Nov 10 - Nov 11
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 2 conference rooms, free WiFi in public areas, and express check-in. ...
8/10 Very Good! (2,179 reviews)
"Excellent"

Reviewed on Oct 13, 2025

Opens in a new windowHampton Inn San Diego-Downtown
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

1646 Front St, San Diego, CA
Fully refundable
$139 nightly
The price is $161 total per night from Nov 20 to Nov 21
$161 total
Nov 20 - Nov 21
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free internet ...
8/10 Very Good! (1,120 reviews)
"Amazing staff! From front desk to dinning and bar area! Safe area, walking distance to restaurants"

Reviewed on Oct 20, 2025

Opens in a new windowCourtyard by Marriott San Diego Downtown Little Italy
Harborview Inn & Suites San Diego Harbor

Harborview Inn & Suites San Diego Harbor

550 West Grape St, San Diego, CA
$93 nightly
The price is $106 total per night from Oct 21 to Oct 22
$106 total
Oct 21 - Oct 22
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the express check-in. Express ...
7/10 Good! (1,007 reviews)
"Old place, great customer service, amazing location"

Reviewed on Oct 13, 2025

Opens in a new windowHarborview Inn & Suites San Diego Harbor
Motel 6 San Diego Airport - Harbor

Motel 6 San Diego Airport - Harbor

2353 Pacific Highway, San Diego, CA
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $88 total per night from Oct 26 to Oct 27
$88 total
Oct 26 - Oct 27
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this motel. WiFi in public areas is free. Staff at the 24-hour front desk can provide ...
6.8/10 (1,013 reviews)
Like this place a lit.
"Easy check- in. Friendly and fast."

Reviewed on Oct 15, 2025

Opens in a new windowMotel 6 San Diego Airport - Harbor
Porto Vista Hotel Downtown

Porto Vista Hotel Downtown

1835 Columbia St, San Diego, CA
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $117 total per night from Oct 22 to Oct 23
$117 total
Oct 22 - Oct 23
Total with taxes and fees
A restaurant and a rooftop terrace are featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
6.6/10 (1,185 reviews)
"Close to Little Italy in San Diego, Easy walk to restaurants and shops"

Reviewed on Oct 16, 2025

Opens in a new windowPorto Vista Hotel Downtown
The Pacific

The Pacific

1655 Pacific Hwy, San Diego, CA
An outdoor pool, free self parking, and concierge services are featured at this hotel. A terrace, express check-out, and luggage storage are also on offer.
"We never went to The Pacific!! We got a text from Expedia telling us the Pacific was closed due to renovations and we were booked at Motel 6 Chula Vista. We paid $50. to take us there only to find out we did not have a reservation. So Expedia has our $274. and we have no accommodations. We rebooked ..."

Reviewed on Oct 8, 2022

Opens in a new windowThe Pacific
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More 4 star hotels in Little Italy

5 star hotels in Little Italy

Little Italy Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Little Italy luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Little Italy to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Little Italy will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Little Italy, and plan your next opulent escape.


Little Italy hotels essential information

Accommodation
8,314 hotels
Lowest Price
$88
Highest Price
$557
Popular hotels
Harborview Inn & Suites San Diego Harbor, Urban Boutique Hotel, Motel 6 San Diego Airport - Harbor, La Pensione Hotel, Porto Vista Hotel Downtown, Hampton Inn San Diego-Downtown, Courtyard by Marriott San Diego Downtown Little Italy, The Pacific

Popular Luxury Stays in Little Italy

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