Book Hotels in Edisto, SC

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight
Nov 20 - Nov 21
Tomorrow
Nov 21 - Nov 22
This weekend
Nov 21 - Nov 23
Next weekend
Nov 28 - Nov 30

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Edisto hotels

Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg

2.5 out of 5
749 Citadel Road Orangeburg SC
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $123 total per night from Dec 21 to Dec 22
$123 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Attentive & welcoming front desk staff member! Our room was spacious, comfortable, clean and quiet!! Met our needs 😊

Reviewed on Nov 12, 2025

Opens in a new windowHampton Inn & Suites Orangeburg
Tru by Hilton Orangeburg

Tru by Hilton Orangeburg

2.5 out of 5
739 Citadel Road Orangeburg SC
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $115 total per night from Nov 30 to Dec 1
$115 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
Room was clean...comfotable

Reviewed on Nov 15, 2025

Opens in a new windowTru by Hilton Orangeburg
Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg

2.5 out of 5
663 Citadel Road Orangeburg SC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $93 total per night from Dec 14 to Dec 15
$93 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Clean room friendly staff

Reviewed on Nov 14, 2025

Opens in a new windowFairfield Inn by Marriott Orangeburg
Comfort Inn & Suites Orangeburg

Comfort Inn & Suites Orangeburg

2.5 out of 5
746 Citadel Rd Orangeburg SC
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $106 total per night from Nov 30 to Dec 1
$106 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
The room was clean, and the bed was comfortable. The staff was friendly and welcoming. The breakfast was pretty good, too.

Reviewed on Nov 14, 2025

Opens in a new windowComfort Inn & Suites Orangeburg
Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg

2 out of 5
3620 Saint Matthews Rd Orangeburg SC
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $75 total per night from Dec 1 to Dec 2
$75 total
Dec 1 - Dec 2
Total with taxes and fees
Free self parking is available and the motel's front desk is staffed around-the-clock. WiFi in public areas is free. Express check-out is also provided.
Not much offered for breakfast.

Reviewed on Nov 16, 2025

Opens in a new windowTravelodge by Wyndham Orangeburg
Spark by Hilton Orangeburg

Spark by Hilton Orangeburg

2.5 out of 5
731 Citadel Road Orangeburg SC
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $97 total per night from Nov 30 to Dec 1
$97 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
Yes mais nous navons pas coucher la car javais reserve et je me suis trompe de date ils nont pas voulus nous accepter et collecter latgent plus tard par Hotel Com. Cest regrettanle jai perdu mon argent je ne pensre plus utileser Hotel.com, Verbo et autres

Reviewed on Nov 12, 2025

Opens in a new windowSpark by Hilton Orangeburg
Super 8 by Wyndham, Orangeburg

Super 8 by Wyndham, Orangeburg

2 out of 5
3608 Saint Matthews Rd Orangeburg SC
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $64 total per night from Nov 30 to Dec 1
$64 total
Nov 30 - Dec 1
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
Room was clean and comfortable. Good value!

Reviewed on Nov 11, 2025

Opens in a new windowSuper 8 by Wyndham, Orangeburg
Days Inn by Wyndham Orangeburg

Days Inn by Wyndham Orangeburg

2 out of 5
3691 Saint Matthews Rd Orangeburg SC
Fully refundableReserve now, pay when you stay
$43 nightly
The price is $48 total per night from Dec 7 to Dec 8
$48 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
The breakfast service was done to early, if possible they should let break go until 10...

Reviewed on Nov 9, 2025

Opens in a new windowDays Inn by Wyndham Orangeburg
Crown Inn By Oyo Orangeburg Hwy 301

Crown Inn By Oyo Orangeburg Hwy 301

2.5 out of 5
2805 Bamberg Rd Orangeburg SC
Fully refundableReserve now, pay when you stay
$53 nightly
The price is $58 total per night from Nov 21 to Nov 22
$58 total
Nov 21 - Nov 22
Total with taxes and fees
Free self parking is available and the hotel's front desk is staffed around-the-clock. WiFi in public areas is free. Express check-out is also provided.
Nothing was placed i ever stayed

Reviewed on Jun 23, 2025

Opens in a new windowCrown Inn By Oyo Orangeburg Hwy 301
Don't see what you're looking for?
See all available properties in Edisto
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Edisto?
Take some of the worries out of traveling with young ones by staying in a family-friendly hotel in Edisto. From well-thought-out amenities to services that bring a smile, these properties feature perks that'll help make your visit run like a dream: Your crew will enjoy staying at Econo Lodge Inn and Suites. Complimentary breakfast and pet-friendly facilities are just a couple of the things that help make this hotel a winner. Also consider Palmetto Inn & Suites by OYO Orangeburg. It comes with front desk services, pet-friendly facilities and plenty of opportunities to hang out as a family.
Where can I find cheap hotels in Edisto?
At Travelocity you'll find really nice hotels in Edisto at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Edisto rather than in Edisto. We may find you even better rates, too.
How do I find the best Edisto hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Edisto then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Edisto?
The cheapest hotel in Edisto is $48. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Edisto?
There are 59 hotels in Edisto on Travelocity.
What are the best hotels in Edisto?
Edisto has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Edisto for you!
When is the best time to visit Edisto?
If you want the joy of a fun-filled trip in peak season, visit Edisto during March, April and August. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, September and December.
When is the cheapest time to stay in Edisto?
Based on historic data is usually the cheapest month to visit Edisto. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Edisto?
There are multiple hotels in Edisto that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Edisto. We have plenty of kid-friendly hotels in Edisto to choose from on Travelocity!
Why book a hotel in Edisto through Travelocity?
Because we have the top hotels in Edisto! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Edisto on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Edisto hotel reviews by fellow wanderers

Sleep Inn Orangeburg

Sleep Inn Orangeburg

5 out of 5
Posted 3 days ago
Travelocity Verified Review
"The staff was absolutely amazing! Marquita went above and beyond to handle a situation and it hasn't gone unnoticed! We will definitely stay again!"
A verified traveler stayed at Sleep Inn Orangeburg
Sleep Inn Orangeburg