Book Hotels in De Soto, IL

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Top De Soto hotels

Walker's Bluff Casino Resort

Walker's Bluff Casino Resort

4.5 out of 5
777 Walkers Bluff Way Carterville IL
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $128 total per night from Aug 24 to Aug 25
$128 total
Aug 24 - Aug 25
Total with taxes and fees
This luxury resort features a casino, a full-service spa, and 3 restaurants. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
"The hotel was amazing"

Reviewed on Aug 19, 2026

Opens in a new windowWalker's Bluff Casino Resort
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 out of 5
120 MUDDY MONSTER ROAD Murphysboro IL
Fully refundable
$114 nightly
The price is $127 total per night from Aug 23 to Aug 24
$127 total
Aug 23 - Aug 24
Total with taxes and fees
A restaurant and an indoor pool are featured at this hotel. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate freebies ...
"We stayed at several hotels during our recent road trip. Holiday Inn had the best breakfast by far."

Reviewed on Aug 16, 2026

Opens in a new windowHoliday Inn Express & Suites Murphysboro - Carbondale by IHG
Holiday Inn Express & Suites Carbondale - University Area by IHG

Holiday Inn Express & Suites Carbondale - University Area by IHG

3 out of 5
2300 Reed Station Parkway Carbondale IL
Fully refundable
$111 nightly
The price is $128 total per night from Sep 20 to Sep 21
$128 total
Sep 20 - Sep 21
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free ...
"Clean"

Reviewed on Aug 20, 2026

Opens in a new windowHoliday Inn Express & Suites Carbondale - University Area by IHG
Super 8 by Wyndham Carbondale

Super 8 by Wyndham Carbondale

2 out of 5
1180 E Main St Carbondale IL
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $78 total per night from Sep 9 to Sep 10
$78 total
Sep 9 - Sep 10
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Multilingual staff at the 24-hour front desk ...
"No frills. Great place if you need a plce to lay your head for a few nights. I have stayed here multiple time and always found the staff very nice."

Reviewed on Aug 17, 2026

Opens in a new windowSuper 8 by Wyndham Carbondale
Baymont by Wyndham Marion

Baymont by Wyndham Marion

2.5 out of 5
2608 W Main St Marion IL
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $105 total per night from Sep 7 to Sep 8
$105 total
Sep 7 - Sep 8
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Opens in a new windowBaymont by Wyndham Marion
Drury Inn & Suites Marion

Drury Inn & Suites Marion

3 out of 5
2706 W DeYoung St Marion IL
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $127 total per night from Aug 30 to Aug 31
$127 total
Aug 30 - Aug 31
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Opens in a new windowDrury Inn & Suites Marion
Best Western Marion Hotel

Best Western Marion Hotel

2.5 out of 5
400 Comfort Dr Marion IL
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $91 total per night from Aug 23 to Aug 24
$91 total
Aug 23 - Aug 24
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Opens in a new windowBest Western Marion Hotel
Comfort Inn & Suites Marion I-57

Comfort Inn & Suites Marion I-57

2.5 out of 5
2403 Black Diamond Dr Marion IL
Fully refundable
$113 nightly
The price is $135 total per night from Sep 20 to Sep 21
$135 total
Sep 20 - Sep 21
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Opens in a new windowComfort Inn & Suites Marion I-57
Home2 Suites by Hilton Carbondale

Home2 Suites by Hilton Carbondale

3 out of 5
200 W Elm St Carbondale IL
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $122 total per night from Aug 30 to Aug 31
$122 total
Aug 30 - Aug 31
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Opens in a new windowHome2 Suites by Hilton Carbondale
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in De Soto?
Family vacations are where lifelong memories are made, but traveling with children can be daunting. These kid-friendly De Soto hotels offer perks designed to keep old and young alike comfortable and happy: The whole gang will love staying at Shady Lakes Escape-w/n minutes from Wineries & Lakes!. A playground and a nearby beach are just a couple of the things that help make this hotel a winner. Also look into This Cobbleston Mid-Century Home Offers 4 Bedrooms on One Level. It offers a swimming pool, animal viewing activities and lots of opportunities to hang out as a family.
Where can I find cheap hotels in De Soto?
At Travelocity you'll find really nice hotels in De Soto at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near De Soto rather than in De Soto. We may find you even better rates, too.
How do I find the best De Soto hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in De Soto then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in De Soto?
The cheapest hotel in De Soto is $78. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in De Soto?
There are 252 hotels in De Soto on Travelocity.
What are the best hotels in De Soto?
De Soto has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in De Soto for you!
When is the best time to visit De Soto?
If you want the joy of a fun-filled trip in peak season, visit De Soto during May, June and August. If you'd prefer the peace of off-season, book a stay during quieter months, such as December, January and February.
When is the cheapest time to stay in De Soto?
Based on historic data is usually the cheapest month to visit De Soto. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in De Soto?
There are multiple hotels in De Soto that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to De Soto. We have plenty of kid-friendly hotels in De Soto to choose from on Travelocity!
Why book a hotel in De Soto through Travelocity?
Because we have the top hotels in De Soto! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in De Soto on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent De Soto hotel reviews by fellow wanderers

Holiday Inn Express & Suites Carbondale - University Area by IHG

Holiday Inn Express & Suites Carbondale - University Area by IHG

5 out of 5
Posted 20 hours ago
Travelocity Verified Review
"Love the clean room and friendly staff."
A verified traveler stayed at Holiday Inn Express & Suites Carbondale - University Area by IHG
Holiday Inn Express & Suites Carbondale - University Area by IHG