Book Hotels in Lower Matecumbe Key, FL
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Top Lower Matecumbe Key hotels

Matecumbe Resort
76261 Overseas Hwy, Islamorada, FL
$107 nightly
The price is $121 total per night from Sep 3 to Sep 4
$121 total
Sep 3 - Sep 4
Total with taxes and fees
A private beach and an outdoor pool are featured at this smoke-free resort. Guests will appreciate free perks like free self parking and WiFi in public areas. ...

Oceanfront 165ft beach-Dock-Heated pool-4K sq.ft 4 bed/5 bath-Next avail 8.9.25
Islamorada
A water park and an outdoor pool are featured at this smoke-free vacation home. Enjoy the a rooftop terrace and perks like free WiFi. A garden, laundry facilities, ...

Chesapeake Beach Resort
83409 Overseas Hwy, Islamorada, FL
Fully refundableReserve now, pay when you stay
$170 nightly
The price is $192 total per night from Sep 16 to Sep 17
$192 total
Sep 16 - Sep 17
Total with taxes and fees
A private beach, a marina, and 2 outdoor pools are all featured at this smoke-free hotel. Enjoy a day at the beach kayaking, or relax with sun loungers. Unwind ...

Cheeca Lodge & Spa
81801 Overseas Highway, Mile Marker 82, Marker 82, Islamorada, FL
Fully refundableReserve now, pay when you stay
$187 nightly
The price is $211 total per night from Sep 4 to Sep 5
$211 total
Sep 4 - Sep 5
Total with taxes and fees
This luxury resort features a private beach, a golf course, and a full-service spa. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...

Baker's Cay Resort Key Largo, Curio Collection by Hilton
97000 Overseas Hwy, Key Largo, FL
Fully refundableReserve now, pay when you stay
$303 nightly
The price is $341 total per night from Sep 9 to Sep 10
$341 total
Sep 9 - Sep 10
Total with taxes and fees
A private beach, 2 restaurants, and 2 outdoor pools are all featured at this resort. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...

Amara Cay Resort
80001 Overseas Hwy, Islamorada, FL
$246 nightly
The price is $276 total per night from Sep 7 to Sep 8
$276 total
Sep 7 - Sep 8
Total with taxes and fees
A private beach, 2 restaurants, and an outdoor pool are all featured at this resort. If you want to take your pet along, this pet-friendly property offers everything ...

Hawks Cay Resort
61 Hawks Cay Blvd, Marathon, FL
Fully refundableReserve now, pay when you stay
$266 nightly
The price is $298 total per night from Sep 8 to Sep 9
$298 total
Sep 8 - Sep 9
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...

Islander Resort
82100 Overseas Highway, Islamorada, FL
Fully refundableReserve now, pay when you stay
$215 nightly
The price is $242 total per night from Sep 8 to Sep 9
$242 total
Sep 8 - Sep 9
Total with taxes and fees
A private beach, 3 restaurants, and 2 outdoor pools are all featured at this hotel. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Families ...

Treasure Harbor
200 Treasure Harbor Dr, Islamorada, FL
$215 nightly
The price is $242 total per night from Sep 3 to Sep 4
$242 total
Sep 3 - Sep 4
Total with taxes and fees
Free WiFi in public areas is available at this hotel. Take advantage of the free self parking.
Don't see what you're looking for?
See all available properties in Lower Matecumbe Key
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Lower Matecumbe Key with star-rating
Check Lower Matecumbe Key Hotels by Star Rating

5 Star Hotels
3 properties
Explore More Ways to Travel with Travelocity
Explore More Ways to Travel with Travelocity
- Types of hotels
- Hotels near…
- Top hotel brands
- Hotels by star rating
- Areas of Lower Matecumbe Key
- Book on Expedia
An Attraction
- Hotels near Anne's Beach
- Hotels near Sunset Drive Beach
- Hotels near Everglades National Park
- Hotels near Fiesta Key
- Hotels near Curry Hammock State Park
- Hotels near Coco Plum Beach
- Hotels near Bud n' Mary's Dive Center
- Hotels near Long Key State Park
- Hotels near Founders Park
- Hotels near Harry Harris Park
- Hotels near Florida Keys Brewing Co.
- Hotels near Florida Keys Dive Center
- Hotels near Little Conch Key
- Hotels near Windley Key Fossil Reef Geological State Park
- Hotels near Pigeon Key
- Hotels near Matecumbe United Methodist Church
- Key Largo Hotels
- Marathon Hotels
- Islamorada Hotels
- Florida Keys Hotels
- Tavernier Hotels
- Long Key Hotels
- Duck Key Hotels
- South Florida Hotels
- Flamingo Hotels
- Rock Harbor Hotels
- Grassy Key Hotels
- Layton Hotels
- Southeastern United States Hotels
- Conch Key Hotels
- Gulf of Mexico Hotels
- Plantation Key Hotels
- Upper Matecumbe Key Hotels
- The South Hotels
- Windley Key Hotels
- Lignumvitae Key Botanical State Park Hotels
- Lower Arsnicker Keys Hotels
- Hotels in Long Key
- Houseboats in Islamorada
- Hotels in Layton
- Luxury Hotels in Islamorada
- Oceanfront Hotels in Islamorada
- Flights to Islamorada
- Resorts in Islamorada
- Islamorada vacation rentals
- Beach Hotels in Islamorada
- Islamorada vacations
- Pet-friendly Hotels in Islamorada
- Cheap Hotels in Islamorada
- Cottages in Islamorada
- Motels in Islamorada
- Hotels in Islamorada
Most popular
Hotels
- Apartments Flagstaff
- Grand Hotel Quisisana
- Embassy Suites by Hilton Jacksonville Baymeadows
- Hotels around Donald E. Stephens Convention Center
- InTown Suites Extended Stay Select Charlotte NC - University
- Hotels around Ethel Barrymore Theatre
- Condos Gulf Shores
- Breathless Riviera Cancun Resort & Spa - Adults Only - All Inclusive
- Hotels around Fenway Park
- Extended Stay Hotels San Clemente
- Cheap Hotels in Scotch Plains
- Solaire Resort Entertainment City
Flights
- United Denver (DEN) to Los Angeles (LAX) flights
- Delta Orlando (MCO) to Chattanooga (CHA) flights
- Fiji Airways Atlanta (ATL) to Nadi (NAN) flights
- MAF to IAH Flights
- CXR to SFO Flights
- American Airlines Philadelphia (PHL) to Ho Chi Minh City (SGN) flights
- LGA to MIA Flights
- GCK to MIA Flights
- JetBlue Airways Oakland (OAK) to Boston (BOS) flights
- FNT to SAV Flights
- American Airlines Ladyville (BZE) to Miami (MIA) flights
- CVG to MLE Flights
- American Airlines San Antonio (SAT) to Los Angeles (ONT) flights
- United Houston (IAH) to Hayden (HDN) flights
- TLH to GPT Flights
Activities