Explore top 2026 5 Star Hotels in Panama City

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Top Panama City 5 Star hotels

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $151 total per night from May 5 to May 6
$151 total
May 5 - May 6
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9/10 Wonderful! (5,310 reviews)
Good

Reviewed on Apr 14, 2026

Opens in a new windowHotel Riu Plaza Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street Panama City Panama
Fully refundableReserve now, pay when you stay
$265 nightly
The price is $292 total per night from May 1 to May 2
$292 total
May 1 - May 2
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, kid-friendly ...
9/10 Wonderful! (1,003 reviews)
we stayed four nights and everything was to our expectation. Clean room nice staff. Only the city view was having an other building right in front of our window.

Reviewed on Apr 3, 2026

Opens in a new windowWaldorf Astoria Panama
W Panama

W Panama

5 out of 5
Calle Aquilino de la Guardia & Calle 50 Panama City
Fully refundableReserve now, pay when you stay
$239 nightly
The price is $263 total per night from May 2 to May 3
$263 total
May 2 - May 3
Total with taxes and fees
This luxury hotel features 2 restaurants, 3 hot tubs, and an outdoor pool. Make the most of the gym and a rooftop terrace, and relax with drinks at one of the ...
9/10 Wonderful! (1,003 reviews)
They did.

Reviewed on Apr 13, 2026

Opens in a new windowW Panama
Hyatt Regency Panama City

Hyatt Regency Panama City

5 out of 5
Calle 52 and Ricardo Arias Panama City
Fully refundableReserve now, pay when you stay
$158 nightly
The price is $173 total per night from May 1 to May 2
$173 total
May 1 - May 2
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public ...
9.6/10 Exceptional! (256 reviews)
I Loved my stay at the Hyatt Regency! Very clean environment and the food was great. Oh and the staff were so friendly! Will be back soon!

Reviewed on Apr 11, 2026

Opens in a new windowHyatt Regency Panama City
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica Panama City Panama
Fully refundableReserve now, pay when you stay
$247 nightly
The price is $272 total per night from May 3 to May 4
$272 total
May 3 - May 4
Total with taxes and fees
This luxury hotel features 3 restaurants, 4 outdoor pools, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express ...
9/10 Wonderful! (1,028 reviews)
Very clean room, staff is very

Reviewed on Apr 14, 2026

Opens in a new windowJW Marriott Panama
Renaissance Panama City Hotel

Renaissance Panama City Hotel

5 out of 5
Via España & Ricardo Arias Street Panama City Panama
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $140 total per night from Apr 20 to Apr 21
$140 total
Apr 20 - Apr 21
Total with taxes and fees
A casino and an outdoor pool are featured at this luxury hotel. Families will appreciate the arcade/game room, onsite laundry facilities, and in-room childcare. ...
8.8/10 Excellent! (186 reviews)
Room was outdated, no facial mirror, poor lighting and too few towel bars.

Reviewed on Apr 11, 2026

Opens in a new windowRenaissance Panama City Hotel
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

5 out of 5
Km 6 Road to Veracruz Veracruz Panama
Fully refundableReserve now, pay when you stay
$202 nightly
The price is $222 total per night from Apr 30 to May 1
$222 total
Apr 30 - May 1
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and 4 restaurants. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. There's ...
8/10 Very Good! (1,020 reviews)
Kids club was closed off. Also someone stole my sneakers and daughter's crocs. Hotel staff didnt seem to care

Reviewed on Apr 14, 2026

Opens in a new windowThe Westin Playa Bonita Panama
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

5 out of 5
Calle Primera Oeste, San Felipe Panama City Panama
Fully refundableReserve now, pay when you stay
$356 nightly
The price is $391 total per night from Apr 26 to Apr 27
$391 total
Apr 26 - Apr 27
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.8/10 Exceptional! (631 reviews)
when we arrived the check in was not ideal. The room we initially received was not clean and the windows were very dirty. The reception was with a staff named jesus and was very bad, After we complained they changed our room and the second room was ok.

Reviewed on Apr 8, 2026

Opens in a new windowSofitel Legend Casco Viejo, Panama City
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

5 out of 5
Avenida Aquilino de La Guardia Panama City Panama
Fully refundableReserve now, pay when you stay
$200 nightly
The price is $220 total per night from May 7 to May 8
$220 total
May 7 - May 8
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...
9.4/10 Exceptional! (1,019 reviews)
Breakfast buffet was excellent. Staff cordial. Bar excellent. Restaurant excellent.

Reviewed on Apr 13, 2026

Opens in a new windowBristol Panama, a Registry Collection Hotel
Hilton Panama

Hilton Panama

5 out of 5
Balboa Ave. and Aquilino De La Guardia Panama City
Fully refundableReserve now, pay when you stay
$234 nightly
The price is $257 total per night from May 1 to May 2
$257 total
May 1 - May 2
Total with taxes and fees
This luxury hotel features an attached winery, a casino, and a full-service spa. Families will appreciate the onsite laundry facilities and babysitting. Enjoy ...
9/10 Wonderful! (1,009 reviews)
I must say I was disappointed the way Expedia handled it. It appeared, Hilton has 2 types of Master suites - with a balcony and without one. Expedia posts photos with the balcony, I expect the balcony, I really needed it to have some room for myself when all the family sleeps. But Hilton puts me ...

Reviewed on Apr 10, 2026

Opens in a new windowHilton Panama
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Panama City Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Panama City to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Panama City 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Panama City before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Panama City hotel reviews by fellow wanderers

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

5 out of 5
Posted 3 hours ago
Travelocity Verified Review
"Everything was great"
A verified traveler stayed at Ramada Plaza by Wyndham Panama Punta Pacifica
Ramada Plaza by Wyndham Panama Punta Pacifica

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