Explore West Main Historic District Spa Hotels & Wellness Resorts

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Top West Main Historic District Spa Resorts & Hotels

21c Museum Hotel Louisville

21c Museum Hotel Louisville

4.5 out of 5
700 W Main Street, Louisville, KY
Free Cancellation
Reserve now, pay when you stay
$125 nightly
The price is $147 total per night
$147 total
Aug 11 - Aug 12
Total includes taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
Louisville Marriott Downtown

Louisville Marriott Downtown

4 out of 5
280 West Jefferson Street, Louisville, KY
Free Cancellation
Reserve now, pay when you stay
$159 nightly
The price is $187 total per night
$187 total
Aug 1 - Aug 2
Total includes taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street, Louisville, KY
$140 nightly
The price is $164 total per night
$164 total
Aug 10 - Aug 11
Total includes taxes and fees
A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Residence Inn by Marriott Louisville Downtown

Residence Inn by Marriott Louisville Downtown

3 out of 5
333 East Market Street, Louisville, KY
Free Cancellation
Reserve now, pay when you stay
$96 nightly
The price is $113 total per night
$113 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown

4 out of 5
500 S 4th St, Louisville, KY
Free Cancellation
Reserve now, pay when you stay
$168 nightly
The price is $198 total per night
$198 total
Jul 21 - Jul 22
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, express check-out, and ...
Don't see what you're looking for?
See all available properties in West Main Historic District
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

West Main Historic District hotels essential information

Accommodation
1,998 hotels
Lowest Price
$113
Highest Price
$198
Popular hotels
Galt House Hotel Trademark Collection by Wyndham, 21c Museum Hotel Louisville, Louisville Marriott Downtown, Residence Inn by Marriott Louisville Downtown, Seelbach Hilton Louisville Downtown

Recent West Main Historic District hotel reviews by fellow wanderers

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Great Location and was clean throughout "
A verified traveler stayed at Galt House Hotel Trademark Collection by Wyndham
Galt House Hotel Trademark Collection by Wyndham
21c Museum Hotel Louisville

21c Museum Hotel Louisville

5 out of 5
Posted 4 days ago
Travelocity Verified Review
"Great Location. Great hotel. Great team members."
A verified traveler stayed at 21c Museum Hotel Louisville
21c Museum Hotel Louisville