Hotels with Air Conditioning in Upstate South Carolina from $66

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Top Upstate South Carolina Hotels with Air Conditioning

AC Hotel by Marriott Spartanburg

AC Hotel by Marriott Spartanburg

3.5 out of 5
225 West Main Street Spartanburg SC
Free Cancellation
Reserve now, pay when you stay
$119 nightly
The price is $132 total per night
$132 total
Dec 21 - Dec 22
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi ...
Aloft Greenville Downtown

Aloft Greenville Downtown

3 out of 5
5 North Laurens Street Greenville SC
Free Cancellation
Reserve now, pay when you stay
$125 nightly
The price is $138 total per night
$138 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Best Western Plus Spartanburg

Best Western Plus Spartanburg

2.5 out of 5
125 Sloane Garden Rd Spartanburg SC
Free Cancellation
Reserve now, pay when you stay
$84 nightly
The price is $94 total per night
$94 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall

2.5 out of 5
246 Congaree Road Greenville SC
Free Cancellation
Reserve now, pay when you stay
$84 nightly
The price is $92 total per night
$92 total
Dec 13 - Dec 14
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood

3 out of 5
40 W Orchard Park Dr Greenville SC
Free Cancellation
Reserve now, pay when you stay
$84 nightly
The price is $92 total per night
$92 total
Jan 12 - Jan 13, 2026
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Best Western Greenville Airport Inn

Best Western Greenville Airport Inn

2.5 out of 5
5009 Pelham Road Greenville SC
Free Cancellation
Reserve now, pay when you stay
$72 nightly
The price is $79 total per night
$79 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Free perks include full breakfast, free self parking, and a roundtrip airport shuttle. A 24-hour business ...
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd Anderson SC
Free Cancellation
Reserve now, pay when you stay
$63 nightly
The price is $70 total per night
$70 total
Dec 14 - Dec 15
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Baymont by Wyndham Easley/Greenville

Baymont by Wyndham Easley/Greenville

2.5 out of 5
211 Dayton School Rd Easley SC
Free Cancellation
Reserve now, pay when you stay
$75 nightly
The price is $83 total per night
$83 total
Dec 13 - Dec 14
Total with taxes and fees
This motel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Econo Lodge

Econo Lodge

2 out of 5
106 Liberty Dr Clemson SC
Free Cancellation
Reserve now, pay when you stay
$77 nightly
The price is $85 total per night
$85 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...
Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson

2.5 out of 5
128 Interstate Blvd Anderson SC
Free Cancellation
Reserve now, pay when you stay
$60 nightly
The price is $66 total per night
$66 total
Jan 12 - Jan 13, 2026
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Baymont by Wyndham Greenville Woodruff Rd

Baymont by Wyndham Greenville Woodruff Rd

2.5 out of 5
31 Old Country Rd Greenville SC
Free Cancellation
Reserve now, pay when you stay
$66 nightly
The price is $73 total per night
$73 total
Dec 18 - Dec 19
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Days Inn by Wyndham Greenville

Days Inn by Wyndham Greenville

2 out of 5
60 Roper Mountain Rd Greenville SC
Free Cancellation
Reserve now, pay when you stay
$60 nightly
The price is $66 total per night
$66 total
Dec 14 - Dec 15
Total with taxes and fees
This motel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Upstate South Carolina hotels essential information

Accommodation
2,914 hotels
Lowest Price
$66
Highest Price
$138
Popular hotels
Comfort Inn Greenville - Haywood Mall, Hyatt Place Greenville/Haywood, Days Inn by Wyndham Greenville, Best Western Greenville Airport Inn, AC Hotel by Marriott Spartanburg, Aloft Greenville Downtown, Econo Lodge, Best Western Plus Spartanburg, Days Inn by Wyndham Anderson, Baymont by Wyndham Easley/Greenville, Baymont by Wyndham Greenville Woodruff Rd, Baymont by Wyndham Anderson Clemson

Recent Upstate South Carolina hotel reviews by fellow wanderers

Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood

5 out of 5
Posted 3 days ago
Travelocity Verified Review
"The room was very nice. Very spacious. The staff was very friendly. The location was great too. "
A verified traveler stayed at Hyatt Place Greenville/Haywood
Hyatt Place Greenville/Haywood

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