Explore 34 Luxury Hotels in San Luis Obispo Wine Country

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Best Luxury Hotels in San Luis Obispo Wine Country

Avila La Fonda Hotel

Avila La Fonda Hotel

101 San Miguel St, Avila Beach, CA
Fully refundableReserve now, pay when you stay
$192 nightly
The price is $217 total per night from Dec 9 to Dec 10
$217 total
Dec 9 - Dec 10
Total with taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free continental breakfast each morning. A snack bar/deli, ...
9.4/10 Exceptional! (1,001 reviews)
The friendliness of the staff, how cozy the place was, and how close the beach was to the hotel.

Reviewed on Nov 13, 2025

Opens in a new windowAvila La Fonda Hotel
San Luis Creek Lodge

San Luis Creek Lodge

1941 Monterey Street San Luis Obispo CA
Fully refundableReserve now, pay when you stay
$165 nightly
The price is $188 total per night from Nov 17 to Nov 18
$188 total
Nov 17 - Nov 18
Total with taxes and fees
This bed & breakfast doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Express check-out is also provided.
9.4/10 Exceptional! (1,001 reviews)
Cute, charming, nice decor and desirable location.

Reviewed on Nov 11, 2025

Opens in a new windowSan Luis Creek Lodge
Madonna Inn

Madonna Inn

100 Madonna Road San Luis Obispo CA
Fully refundableReserve now, pay when you stay
$167 nightly
The price is $190 total per night from Dec 14 to Dec 15
$190 total
Dec 14 - Dec 15
Total with taxes and fees
A full-service spa, 2 restaurants, and 2 outdoor tennis courts are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour ...
9.2/10 Wonderful! (1,298 reviews)
First time to stay & was an enjoyable one! Very unique with all the different room themes/styles. E stayed at one of the French-themed rooms. Enjoyed breakfast, too, fast and generous portions. Our server, Amanda, was very friendly and helpful! Would definitely stay here, again, in the future!!

Reviewed on Nov 14, 2025

Opens in a new windowMadonna Inn
Avenue Inn Downtown San Luis Obispo

Avenue Inn Downtown San Luis Obispo

345 Marsh St San Luis Obispo CA
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $82 total per night from Dec 14 to Dec 15
$82 total
Dec 14 - Dec 15
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A grocery/convenience store, express check-out, and luggage storage are ...
9/10 Wonderful! (1,124 reviews)
For a basic motel this property checked all the important boxes. Location is only a few blocks from historic downtown S.L.O. Bed was comfortable enough. There was an extra blanket available (which I used). Shower, toilet, and bathroom fan functioned well. Separate area for sink was convenient. There ...

Reviewed on Nov 13, 2025

Opens in a new windowAvenue Inn Downtown San Luis Obispo
La Cuesta Inn, BW Signature Collection

La Cuesta Inn, BW Signature Collection

2074 Monterey Street San Luis Obispo CA
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $111 total per night from Nov 30 to Dec 1
$111 total
Nov 30 - Dec 1
Total with taxes and fees
A nightclub and an outdoor pool are featured at this smoke-free hotel. Enjoy the hot tub and free perks like continental breakfast and free self parking. Free ...
8.6/10 Excellent! (1,061 reviews)
Staff was very quiet

Reviewed on Nov 12, 2025

Opens in a new windowLa Cuesta Inn, BW Signature Collection
Vagabond Inn San Luis Obispo

Vagabond Inn San Luis Obispo

210 Madonna Rd San Luis Obispo CA
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $79 total per night from Nov 30 to Dec 1
$79 total
Nov 30 - Dec 1
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the express check-out. A restaurant, ...
8.4/10 Very Good! (1,173 reviews)
very comfortable beds, and very clean rooms. wonderful service.

Reviewed on Nov 6, 2025

Opens in a new windowVagabond Inn San Luis Obispo
Inn at San Luis Obispo

Inn at San Luis Obispo

1895 Monterey Street San Luis Obispo CA
$59 nightly
The price is $67 total per night from Nov 30 to Dec 1
$67 total
Nov 30 - Dec 1
Total with taxes and fees
This motel features an outdoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self parking, ...
7.6/10 Good! (1,005 reviews)
clean room, very quiet

Reviewed on Nov 4, 2025

Opens in a new windowInn at San Luis Obispo
Hotel Calle Joaquin

Hotel Calle Joaquin

1585 Calle Joaquin San Luis Obispo CA
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $85 total per night from Nov 16 to Nov 17
$85 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel features an outdoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self parking, ...
7.2/10 Good! (689 reviews)
The room was a decent size. The floors were a little dirty, and the shower wasn't that great.

Reviewed on Nov 10, 2025

Opens in a new windowHotel Calle Joaquin
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More 4 star hotels in San Luis Obispo Wine Country

San Luis Obispo Wine Country Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the San Luis Obispo Wine Country luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in San Luis Obispo Wine Country to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in San Luis Obispo Wine Country will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in San Luis Obispo Wine Country, and plan your next opulent escape.


San Luis Obispo Wine Country hotels essential information

Accommodation
1,879 hotels
Lowest Price
$67
Highest Price
$304
Popular hotels
Madonna Inn, Avenue Inn Downtown San Luis Obispo, Avila La Fonda Hotel, Hotel Calle Joaquin, San Luis Creek Lodge, La Cuesta Inn, BW Signature Collection, Vagabond Inn San Luis Obispo, Inn at San Luis Obispo

Popular Luxury Stays in San Luis Obispo Wine Country

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