Explore 390 Luxury Hotels in Rome City Centre

Name: Villa Agrippina Gran Meliá - The Leading Hotels of the World
Price range: $765 total

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Best Luxury Hotels in Rome City Centre

The Westin Excelsior, Rome

Via Vittorio Veneto 125, Rome, RM

Fully refundableReserve now, pay when you stay

$581 nightly

$662 total

Sep 5 - Sep 6

Total with taxes and fees

A full-service spa, an indoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...

8.2/10 Very Good! (722 reviews)

5 stars

"Just gorgeous from the first night to the last. The concierge helped us so many times - getting taxis, arranging for a trip to the beach. We are a family of 5, and had 2 adjoining rooms....it was just perfect for us. Huge lobby, breakfast was delightful."

Reviewed on Aug 22, 2025

Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

Piazza Della Repubblica, 47, Rome, RM

Fully refundableReserve now, pay when you stay

$739 nightly

$836 total

Aug 31 - Sep 1

Total with taxes and fees

A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free WiFi in ...

The First Arte - Preferred Hotels & Resorts

Via del Vantaggio 14, Rome, RM

Fully refundableReserve now, pay when you stay

$561 nightly

$640 total

Aug 30 - Aug 31

Total with taxes and fees

This smoke-free hotel features 2 restaurants, a bar/lounge, and a gym. Enjoy the a rooftop terrace and perks like free WiFi. A terrace, limo/town car service, ...

Hotel Splendide Royal - The Leading Hotels of the World

Via Di Porta Pinciana 14, Rome, RM

Fully refundableReserve now, pay when you stay

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport ...

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Hotel Majestic Roma

Via Vittorio Veneto 50, Rome, RM

This hotel features a restaurant, a gym, and a bar/lounge. Families will appreciate the onsite laundry facilities and in-room childcare. Enjoy the a rooftop ...

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Palazzo Dama

Lungotevere Arnaldo da Brescia 2, Rome, RM

Fully refundableReserve now, pay when you stay

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Relax with a drink at the poolside bar and enjoy perks like free WiFi. A garden, a snack ...

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J.K. Place Roma

Via di Monte d'Oro, 30, Rome, RM

Fully refundableReserve now, pay when you stay

$1,029 nightly

$1,156 total

Aug 30 - Aug 31

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Guests will appreciate free perks like full breakfast and WiFi in public areas. A lobby fireplace, ...

Villa Agrippina Gran Meliá - The Leading Hotels of the World

Via del Gianicolo 3, Rome, RM

Fully refundableReserve now, pay when you stay

$674 nightly

$765 total

Aug 31 - Sep 1

Total with taxes and fees

A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Business travelers can take advantage of the free WiFi in public ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Rome City Centre

citizenM Rome Isola Tiberina

LUNGOTEVERE DE CENCI 5-8, Rome, RM

$200 nightly

$238 total

Sep 2 - Sep 3

Total with taxes and fees

9.4/10 Exceptional! (624 reviews)

5 star hotels in Rome City Centre

Hotel Raphaël

Largo Febo, 2-Piazza Navona, Rome, RM

$256 nightly

$304 total

Aug 30 - Aug 31

Total with taxes and fees

9/10 Wonderful! (990 reviews)

Rome City Centre Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Rome City Centre luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Rome City Centre to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Rome City Centre will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Rome City Centre, and plan your next opulent escape.

Rome City Centre hotels essential information

Accommodation	7,900 hotels
Lowest Price	$129
Highest Price	$1,156
Popular hotels	Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World, The First Arte - Preferred Hotels & Resorts, Hotel Splendide Royal - The Leading Hotels of the World, Hotel Majestic Roma, Palazzo Dama, J.K. Place Roma, Villa Agrippina Gran Meliá - The Leading Hotels of the World, The Westin Excelsior, Rome