
Exclusive Calle 50 Vacation Deals
Calle 50 vacation package deals
Price found within the past 48 hours. Click for updated prices.

Hotel Riu Plaza Panama
Bella Vista
Price was $1,018, price is now $711 per person
$711
per person
Nov 30 - Dec 6
found 1 day ago
Roundtrip non-stop flight included
Nashville (BNA) to Panama City (PTY)
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Relax with a drink at the bar/lounge and enjoy the free buffet breakfast each morning.

Central Hotel Panama Casco Viejo
Casco Viejo
Save 100% on your flight
Price was $1,825, price is now $972 per person
$972
per person
Nov 30 - Dec 6
found 1 day ago
Roundtrip non-stop flight included
Nashville (BNA) to Panama City (PTY)
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this Belle Époque hotel. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. Enjoy the 24-hour gym and unwind at the bar/lounge and poolside bar.

Central Hotel Bocas del Toro
Save 100% on your flight
Price was $1,924, price is now $1,120 per person
$1,120
per person
Dec 18 - Dec 21
found 8 hours ago
Roundtrip flight included
Chicago (ORD) to Panama City (PTY)
A marina and a restaurant are featured at this hotel. Enjoy the outdoor pool and free perks like continental breakfast and WiFi in public areas. A bar/lounge, a 24-hour front desk, and dry cleaning are also provided.

Bristol Panama, a Registry Collection Hotel
Bella Vista
Save 100% on your flight
Price was $1,437, price is now $986 per person
$986
per person
Nov 30 - Dec 6
found 1 day ago
Roundtrip non-stop flight included
Nashville (BNA) to Panama City (PTY)
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and airport shuttle. Relax with a drink at one of the 2 bars/lounges and enjoy perks like free valet parking.

Isla Palenque Member of the Cayuga Collection
Save 100% on your flight
Price was $3,938, price is now $2,741 per person
$2,741
per person
Dec 18 - Dec 21
found 8 hours ago
Roundtrip flight included
Chicago (ORD) to Panama City (PTY)
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free lodge. Relax with a drink at the bar/lounge and enjoy perks like free WiFi. A terrace, a garden, and a snack bar/deli are also on offer.

Bambuda Bocas Town - Hostel
Price was $1,382, price is now $975 per person
$975
per person
Dec 6 - Dec 13
found 7 hours ago
Roundtrip flight included
Chicago (ORD) to Panama City (PTY)
A restaurant and a bar/lounge are featured at this hostel. A terrace, a communal living room, and dry cleaning are also on offer.
Top Calle 50 hotel deals

Hotel Riu Plaza Panama
Calle 50, Urb. Marbella, Panama City, Panama
Free Cancellation
Reserve now, pay when you stay
$119 nightly
The price is $131 total per night
$131 total
Oct 5 - Oct 6
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Relax with a drink at the bar/lounge and enjoy the free buffet breakfast each morning.
Pool
Breakfast included

Megapolis Hotel Panamá
Avenida Balboa, Panama City
Free Cancellation
Reserve now, pay when you stay
$125 nightly
The price is $138 total per night
$138 total
Oct 4 - Oct 5
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 3 bars/lounges and enjoy free perks like buffet breakfast and free self parking.
Pool
Hot Tub

Principe Hotel and Suites
Via Argentina, Panama City, Panama
Free Cancellation
Reserve now, pay when you stay
$55 nightly
The price is $61 total per night
$61 total
Oct 1 - Oct 2
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport shuttle. Free self parking, a coffee shop, and a terrace are also offered.
Pool
Parking included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.