Find & compare luxury hotels in Cape Girardeau, MO

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Best Luxury Hotels in Cape Girardeau

Davie School Inn

300 Freeman St, Anna, IL

$159

per night

May 15 - May 16

This bed & breakfast features free self parking and free WiFi in public areas. Enjoy the free full breakfast each morning. A terrace and a picnic area are also provided.

Breakfast included

Free WiFi

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cape Girardeau Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Cape Girardeau luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Cape Girardeau to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Cape Girardeau will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Cape Girardeau, and plan your next opulent escape.