American Airlines Flight 4604 Deals & Information (2026/2027)

Wander Wisely with exceptional service, 24/7 supportOpens in a new window

Feel at ease with free flight cancellations within 24 hours of booking

Change your flight without a fee on select flights

American Airlines Flight 4604 Route Deals From $269

The cheapest prices found with in the last 7 days for return flights were $291 and $269 for one-way flights to LaGuardia for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Nov 18 - Tue, Dec 1
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$291 Roundtrip, found 2 days ago
$291
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Nov 18 from John Glenn Columbus Intl. to LaGuardia, returning Tue, Dec 1, priced at $291 found 2 days ago
Tue, Nov 24 - Tue, Dec 1
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$301 Roundtrip, found 5 hours ago
$301
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Tue, Nov 24 from John Glenn Columbus Intl. to LaGuardia, returning Tue, Dec 1, priced at $301 found 5 hours ago
Sat, Oct 17 - Tue, Oct 20
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$315 Roundtrip, found 4 days ago
$315
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Oct 17 from John Glenn Columbus Intl. to LaGuardia, returning Tue, Oct 20, priced at $315 found 4 days ago
Sat, Dec 5 - Tue, Dec 8
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$318 Roundtrip, found 4 days ago
$318
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Dec 5 from John Glenn Columbus Intl. to LaGuardia, returning Tue, Dec 8, priced at $318 found 4 days ago
Tue, Nov 24 - Tue, Dec 1
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$325 Roundtrip, found 5 hours ago
$325
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Tue, Nov 24 from John Glenn Columbus Intl. to LaGuardia, returning Tue, Dec 1, priced at $325 found 5 hours ago
Sat, Dec 5 - Tue, Dec 8
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$329 Roundtrip, found 4 days ago
$329
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Dec 5 from John Glenn Columbus Intl. to LaGuardia, returning Tue, Dec 8, priced at $329 found 4 days ago
Tue, Nov 24 - Tue, Dec 1
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$335 Roundtrip, found 5 hours ago
$335
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Tue, Nov 24 from John Glenn Columbus Intl. to LaGuardia, returning Tue, Dec 1, priced at $335 found 5 hours ago
Tue, Nov 24 - Tue, Dec 1
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$336 Roundtrip, found 5 hours ago
$336
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Tue, Nov 24 from John Glenn Columbus Intl. to LaGuardia, returning Tue, Dec 1, priced at $336 found 5 hours ago
Thu, Oct 8 - Sat, Oct 10
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$339 Roundtrip, found 2 hours ago
$339
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Thu, Oct 8 from John Glenn Columbus Intl. to LaGuardia, returning Sat, Oct 10, priced at $339 found 2 hours ago
Sat, Dec 19 - Tue, Dec 22
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$341 Roundtrip, found 2 days ago
$341
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Dec 19 from John Glenn Columbus Intl. to LaGuardia, returning Tue, Dec 22, priced at $341 found 2 days ago
Wed, Dec 30 - Sat, Jan 2
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$341 Roundtrip, found 1 day ago
$341
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Dec 30 from John Glenn Columbus Intl. to LaGuardia, returning Sat, Jan 2, priced at $341 found 1 day ago
Sat, Oct 10 - Fri, Oct 16
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$344 Roundtrip, found 1 day ago
$344
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Oct 10 from John Glenn Columbus Intl. to LaGuardia, returning Fri, Oct 16, priced at $344 found 1 day ago
Tue, Nov 24 - Tue, Dec 1
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$345 Roundtrip, found 5 hours ago
$345
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Tue, Nov 24 from John Glenn Columbus Intl. to LaGuardia, returning Tue, Dec 1, priced at $345 found 5 hours ago
Tue, Nov 24 - Tue, Dec 1
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$346 Roundtrip, found 5 hours ago
$346
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Tue, Nov 24 from John Glenn Columbus Intl. to LaGuardia, returning Tue, Dec 1, priced at $346 found 5 hours ago
Thu, Oct 8 - Sat, Oct 10
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$349 Roundtrip, found 2 hours ago
$349
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Thu, Oct 8 from John Glenn Columbus Intl. to LaGuardia, returning Sat, Oct 10, priced at $349 found 2 hours ago

Frequently asked questions

What route does flight number AA4604 take?
AA4604 flies straight between Portland Intl. Jetport Airport (PWM) and O'Hare Airport in about 2 hours and 52 minutes. It can sometimes take other routes though, some of which may be multi-stop trips. Keep this in mind when booking your seat to avoid any confusion.
What kind of plane is on flight number AA4604?
If you're on flight AA4604 from Portland, ME Airport (PWM-Portland Intl. Jetport) to O'Hare Intl. Airport (ORD), you'll likely be jetting off on an Embraer 175. Flight AA4604 serves several routes, but this is the most popular one.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4604 flight with Travelocity, please visit our Customer Service Portal.